A5037125937- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Advanced Drug Delivery Systems
- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Innovative Microfluidic and Catalytic Techniques Innovation
- biodegradable polymer synthesis and properties
- Advanced Sensor and Energy Harvesting Materials
- Drug Solubulity and Delivery Systems
- MXene and MAX Phase Materials
- Surface Modification and Superhydrophobicity
- Hydrogels: synthesis, properties, applications
- Oral and gingival health research
- Oral microbiology and periodontitis research
- Pharmacology and Obesity Treatment
- Dysphagia Assessment and Management
- Advanced Materials and Mechanics
- Graphene research and applications
- Electrohydrodynamics and Fluid Dynamics
- Hormonal and reproductive studies
- Streptococcal Infections and Treatments
- Analytical Chemistry and Chromatography
- Graphene and Nanomaterials Applications
- Chemical Synthesis and Analysis
- Surfactants and Colloidal Systems
Chiang Mai University
2018-2025
With the ability to fabricate personalized dosage forms and considerably shorter manufacturing time, semisolid extrusion (SSE) 3D printing has rapidly grown in popularity recent years as a novel, versatile method that powers wide range of applications pharmaceutical field. In this work, feasibility using SSE fast-disintegrating tablets (FDTs) are pre-filled dosing syringes was evaluated. The novel design approach, 'tablet-in-syringe', aimed ease oral drug administration improve accuracy for...
Extrusion-based 3D printing technology is a relatively new technique that has potential for fabricating pharmaceutical products in various dosage forms. It offers many advantages over conventional manufacturing methods, including more accurate drug dosing, which especially important the drugs require exact tailoring (e.g., narrow therapeutic index drugs). In this work, we have successfully fabricated phenytoin-loaded orodispersible films (ODFs) through syringe extrusion technique. Two...
The application of hydrophilic polymers in designing and three-dimensional (3D) printing pharmaceutical products various dosage forms has recently been paid much attention. Use syringe extrusion 3D technology the fabrication orodispersible films (ODFs) might hold great potential rapid drug delivery, personalized medicine, manufacturing time savings. In this study, feasibility 3D-printed ODFs through a technique using five different (e.g., hydroxypropyl methylcellulose E15, E50, high methoxyl...
The objective of this study was to develop the metronidazole loaded high and low methoxyl pectin films (HM-G-MZ LM-G-MZ) for treatment periodontal disease. were prepared by 3% w/v, glycerin 40% 5% w/v. developed characterized scanning electron microscope evaluated thickness, weight variation, elasticity. showing optimal mechanical properties selected evaluate radial swelling properties, in vitro release antimicrobial activity against Porphyromonas gingivalis Aggregatibacter...
This work presents an innovative application of the sugar templating method to fabricate highly porous floating tablets based on cellulose derivatives for gastroretentive drug delivery systems (GRDDS). Ethyl (EC) and hydroxypropyl methylcellulose (HPMC) were utilized develop formulations that optimize porosity, buoyancy, release. Among tested formulations, E10H5/CPM, consisting 10% w/w EC 5% HPMC loaded with chlorpheniramine maleate (CPM), exhibited most favorable properties, including high...
The objective of the present study was to develop an orally disintegrating film (ODF) for a poorly water-soluble drug, phenytoin (PHT), using cosolvent solubilization technique achieve amorphization followed by preparation ODFs. Eleven formulations were prepared with different polymers, such as polyvinyl alcohol (PVA) and high methoxyl pectin (HMP) solvent casting method. films subjected characterization weight variations, thickness, surface pH, disintegration time mechanical strength...
Depression is a mental illness causing continuous negative feeling and loss of interest affects physical health. Mirtazapine (MTZ) an effective medicine for treating depression, but patients lack compliance. However, transforming pharmaceutical dosage form to orodispersible film (ODF) could resolve this issue. This study aims fabricate ODF-loading mirtazapine, using syringe extrusion 3D printer, compare its properties with the solvent-casting method. The ODFs were prepared by dissolving...
The purpose of this study was to mask the bitter taste nizatidine (NZD) using cation-exchange resins. Amberlite IRP-69 and Dowex-50 containing cross-linked polystyrene backbones were used. drug resin complexes prepared by batch process drug: ratios 1:1, 1:3, 1:5. optimum ratio time required for maximum percentage loading into determined. selected drug-resin evaluated morphology, release, taste. NZD-Dowex complex obtained at a 1:5 stirring 1 h in order get 100% NZD. had spherical shape smooth...
Erectile dysfunction (ED) refers to the inability of penis maintain a firm erection during sexual activity. Mucuna, or
The present study aimed to develop a nicotine microemulsion (NCT-ME) and incorporate it into fast-dissolving film. NCT-ME was prepared by mixing the specified proportions of (NCT), surfactant, co-solvent, water. measured its average droplet size, size distribution, zeta potential, morphology. films were solvent casting technique. characterized morphology, weight, thickness, disintegration time, mechanical strength properties determined NCT loading efficiency in vitro drug release. results...