A5055223563- Drug-Induced Hepatotoxicity and Protection
- Bipolar Disorder and Treatment
- Phytochemicals and Antioxidant Activities
- Shoulder Injury and Treatment
- Orthopedic Surgery and Rehabilitation
- Heavy Metal Exposure and Toxicity
- Essential Oils and Antimicrobial Activity
- Natural Antidiabetic Agents Studies
- Elbow and Forearm Trauma Treatment
- Pesticide Exposure and Toxicity
- Phytochemistry and Biological Activities
- Shoulder and Clavicle Injuries
- Natural Compound Pharmacology Studies
- Nigella sativa pharmacological applications
- Chemotherapy-induced organ toxicity mitigation
- Musculoskeletal synovial abnormalities and treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Bone Tumor Diagnosis and Treatments
- Antioxidant Activity and Oxidative Stress
- Electrolyte and hormonal disorders
- Vitamin C and Antioxidants Research
- Orthopedic Infections and Treatments
- Sarcoma Diagnosis and Treatment
University of Sfax
2011-2024
University of Gafsa
2012-2024
Tunis University
2022
Tunis El Manar University
2022
Hospital Fatuma Bourguiba Monastir
2009-2018
University of Monastir
2012-2018
Université Toulouse III - Paul Sabatier
2007-2014
Université de Toulouse
2007
Hôpital Ambroise-Paré
2007
This study characterized the impact of post-weaning high-fat diet (HFD) and/or permethrin (PER) treatment on heart dysfunction and fibrosis, as well atherogenic risk, in rats by investigating interactions between HFD PER. Our results revealed that PER induced remarkable cardiotoxicity promoting cardiac injury, biomarker leakage into plasma altering rate electrocardiogram pattern, ion levels. increased total cholesterol, triacylglycerols, low-density lipoprotein (LDL) cholesterol levels but...
Virgin olive oil has demonstrated its effective activity against oxidative stress. However, data on the bioactive effect of leaves or their major constituents liver are scarce. The present research work was conducted to evaluate hepatoprotective effects supercritical carbon dioxide (SC-CO2) extracts from fresh and dried hepatotoxicity caused by tetrachloride (CCl4) in rat models. For this purpose, healthy albino rats 180–250 g weight were used. assessment biochemical markers carried out...
Plants provide an alternative source to manage different human disorders due various metabolites. The aim of this study is investigate the phytochemical constituents methanolic extracts Euphorbia retusa and evaluate their antioxidant, anti-inflammatory, analgesic activities. results obtained by HPLC chemical assay reactions have revealed richness extract E. in active compounds, particular polyphenols, flavonoids, tannins. shows significant antioxidant activities vitro , DPPH FRAP assays....
The aim of the current work was to study for first time phytochemical profile Ephedra alata subsp. alenda seeds extract (ESS). characterized using high-performance liquid chromatography coupled electrospray ionization quadropole time-of-flight mass spectrometry (HPLC–ESI–QTOF/MS). antioxidant and antihemolytic properties were evaluated, inhibitory against α-amylase, α-glucosidase, acetylcholinesterase assessed. Chromatographic analysis revealed that ESS rich in bioactive components including...
This study was designed to assess the protective effects of Lycium europaeum methanol extract (LEM) on liver and kidney injuries induced by cisplatin. The phytochemical composition, antioxidant activity, hepatorenal injury biomarkers were investigated. Results revealed that LEM exhibited a significant activity in vitro DPPH radical H 2 O scavenging assays. In animal studies, treatment with significantly reduced cisplatin intoxication serum renal biomarkers. Meanwhile, diminishes effect level...
The current study was designed to investigate the possible mechanism involved in hyperglycemia induced by chronic exposure deltamethrin (DLM) rat and assess whether this damage is amenable modulation Zygophyllum album. DLM, a synthetic pyrethroid pesticide, administrated at dose of 4 mg/kg body mass, during 60 days. Compared with control, DLM showed significant increase blood glucose (p ≤ 0.01) glycosylated hemoglobin levels clear decrease insulin total levels. In addition, hepatic glycogen...
Rhus tripartitum D.C., Anacardiaceae, has traditionally been used in Tunisia against many illnesses. The present study investigates, for the first time, protective effects of methanol extract fruit (MERT) CCl 4 -induced hepatotoxicity and cisplatin-induced nephrotoxicty Wistar rats. ALT, AST, LDH, GGT, creatinin, urea, uric acid levels were studied. changes antioxidant parameters such as malondialdehyde (MDA) protein carbonyl contents also determined. increased MDA (30.97 11.50 nmol MDA/mg...
In recent decades, the use of herbs and plants has been great interest, as they have sources natural products, commonly named bioactive compounds. specific, compounds from Capparaceae family which proved to antioxidant, anti-inflammatory, antimicrobial anti-carcinogenic activities, by several studies. Cleome arabica L. (CA) specie is most used medicinal in Tunisia elsewhere North African countries for treatment various diseases including diabetes, rheumatism, inflammation, cancer, digestive...