A5101496645- Traditional Chinese Medicine Studies
- Bioinformatics and Genomic Networks
- Blood Pressure and Hypertension Studies
- Traditional Chinese Medicine Analysis
- Computational Drug Discovery Methods
- Natural product bioactivities and synthesis
- Acupuncture Treatment Research Studies
- Pharmacological Effects of Natural Compounds
- Metabolomics and Mass Spectrometry Studies
- Plant-based Medicinal Research
- Medicinal Plants and Bioactive Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Complementary and Alternative Medicine Studies
- Hormonal Regulation and Hypertension
- Heart Rate Variability and Autonomic Control
- Flavonoids in Medical Research
- Rheumatoid Arthritis Research and Therapies
- Neurological Disease Mechanisms and Treatments
- Renin-Angiotensin System Studies
- Biofield Effects and Biophysics
- Gene Regulatory Network Analysis
- Medical Research and Treatments
- Ginseng Biological Effects and Applications
- Cytokine Signaling Pathways and Interactions
- Gene expression and cancer classification
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
Western University
2024
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2020-2021
Beijing University of Chinese Medicine
2021
Academia Sinica
2018
Academy of Medical Sciences
2018
China Academy of Chinese Medical Sciences
2018
Beijing Chuiyangliu Hospital
2012
Hypertension is a major public-health issue. Much consensus has been reached in the treatment, and considerable progress made field of antihypertensive drugs. However, standard-reaching rate blood pressure far from satisfaction. Considering these data seriousness effects hypertension on individual society as whole, both economically socially, physicians must look for more effective alternative ways to achieve target pressure. Could treatment be improved by insights traditional Chinese...
Abstract Acupuncture is an important part of Chinese medicine that has been widely used in the treatment inflammatory diseases. During coronavirus disease 2019 (COVID-19) epidemic, acupuncture as a complementary for COVID-19 China. However, underlying mechanism remains unclear. Based on bioinformatics/topology, this paper systematically revealed multi-target mechanisms therapy through text mining, bioinformatics, network topology, etc. Two active compounds produced after and 180 protein...
Gastric cancer (GC) is a heterogeneous disease and leading cause of cancer-related deaths. Discovering robust, clinically relevant molecular classifications critical for guiding personalized therapies GC. Here, we propose refined classification scheme GC using integrated optimal algorithms multi-omics data. Based on the important features mRNA, microRNA, DNA methylation data selected by multivariate Cox regression model, three subtypes linked to distinct clinical outcomes were identified...
Huang-Lian-Jie-Du Decoction (HLJDD) is a "Fangji" made up of well-designed Chinese herb array and widely used to treat ischemic stroke. Here we aimed investigate pharmacological mechanism by introducing an inter-module analysis identify overarching view target profile action mode HLJDD. Stroke-related genes were obtained from OMIM (Online Mendelian Inheritance in Man). And the potential proteins HLJDD identified according TCMsp (Traditional Medicine Systems Pharmacology Database Analysis...