A5100723747- Cardiovascular and exercise physiology
- Exercise and Physiological Responses
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac Ischemia and Reperfusion
- Nitric Oxide and Endothelin Effects
- Asthma and respiratory diseases
- High Altitude and Hypoxia
- Adipose Tissue and Metabolism
- Cardiac Arrest and Resuscitation
- Mitochondrial Function and Pathology
- Respiratory Support and Mechanisms
- Vitamin C and Antioxidants Research
- Dialysis and Renal Disease Management
- Muscle Physiology and Disorders
- Anesthesia and Neurotoxicity Research
- Heme Oxygenase-1 and Carbon Monoxide
- Electron Spin Resonance Studies
- Parathyroid Disorders and Treatments
- Muscle metabolism and nutrition
- Eicosanoids and Hypertension Pharmacology
- Redox biology and oxidative stress
- Sports Performance and Training
- Diet and metabolism studies
- Cardiovascular Effects of Exercise
- Effects of Radiation Exposure
Peking University People's Hospital
2020-2025
Peking University
2020-2025
China Pharmaceutical University
2025
Anhui Medical University
2011-2024
Beijing Jiaotong University
2023
The University of Texas Rio Grande Valley
2023
The University of Texas Health Science Center at Houston
2023
Nanchang University
2016-2022
Arbor Research Collaborative for Health
2021
Guangdong Provincial People's Hospital
2021
Abstract Infections caused by persistent, drug‐resistant bacteria pose significant challenges in inflammation treatment, often leading to severe morbidity and mortality. Herein, the photosensitizer rhodamine derivatives are selected as light‐trapping dye electron‐rich substituent N‐nitrosoaminophen nitric oxide (NO)‐releasing component develop a multifunctional (deep) red‐light activatable NO photocage/photodynamic prodrug for efficient treatment of wounds diabetic foot infections. The...
Hyperphosphatemia in patients undergoing dialysis is not well-controlled. AP306 a pan-inhibitor of phosphate transporters, designed to block the active uptake through gastrointestinal tract. In this phase 2 randomized, active-controlled, open-label study, hemodialysis with serum between 5.5 and 9.0 mg/dl were randomized receive either or sevelamer carbonate for 12 weeks. The primary outcome was change levels from baseline until therapy ceased. initiated at 75 mg adjusted stepwise 125 150...
Skeletal muscles are exposed to increased temperatures during intense exercise, particularly in high environmental temperatures. We hypothesized that heat may directly stimulate the reactive oxygen species (ROS) formation diaphragm (one kind of skeletal muscle) and thus potentially play a role contractile metabolic activity. Laser scan confocal microscopy was used study conversion hydroethidine (a probe for intracellular ROS) ethidium (ET) mouse diaphragm. During 30-min period, (42 degrees...
Superoxide anion radical (O(2)(*-)) is released from skeletal muscle at rest and particularly elevated during conditions of heat stress (42 degrees C). Previous studies have shown that in isolated rat diaphragm O(2)(*-) release not dependent on mitochondrial electron transport, reduced NADP oxidase activity, or the integrity membrane channels. This study hypothesized release, as measured by cytochrome c reduction, linked to metabolism arachidonic acid. Phospholipase A(2) inhibition with...