Background/Aim: A large number of diseases are ascribed to Helicobacter pylori (H. pylori), particularly chronic active gastritis, peptic ulcer disease and gastric cancer. Successful treatment H. infection with antimicrobial agents can lead regression pylori–associated disorders. Antibiotic resistance against is increasing, it necessary find new effective agents. Nigella sativa seed (NS), a commonly used herb, possesses in vitro anti-helicobacter activity. The present study was undertaken...

The sequelae of COVID-19 pneumonia on pulmonary function and airways inflammation are still an area active research.This research aimed to explore the long-term impact lung after three months from recovery.Fifty subjects (age 18-60 years) were recruited classified into two groups: control group (30 subjects) post-COVID-19 (20 patients). Pulmonary tests, spirometry, body plethysmography [lung volumes airway resistance (Raw)], diffusion capacity for carbon monoxide (DLCO), fractional exhaled...

Momordica charantia, commonly known as bitter melon, is a fruiting plant that has been used for several diseases including infectious diseases. In this study, we report the antibacterial, antifungal, and antiviral activity of different melon fruit parts originating from India Saudi Arabia. The in vitro experiments are supported by molecular docking karavilosides to verify their role bioactivity. antimicrobial assays revealed against Candida albicans, Escherichia coli, Staphylococcus aureus....

Nigella sativa and its derivatives have been reported to anti-inflammatory bronchodilator effects, but the effects evaluated in only a few clinical studies.To determine effect of N supplementation on inflammation airways limitation airflow partly controlled asthma patients.Single-blind, placebo-controlled, randomized study.Asthma allergy clinic university hospital eastern Saudi Arabia.Patients were divided into three groups. A control group (n=24) received placebo, while NS-1 NS-2 groups...

<b>Background: </b>Many post-COVID-19 patients experienced long-term effects with symptoms lasting for more than three months including fatigue and dyspnea. There is scarce information in the literature on respiratory muscle strength, lung functions, exercise capacity, degree of dyspnea after two years recovery.<br /> <b>Objectives:</b> This study aims to assess function, COVID-19 infection.<br <b>Methodology:</b> an observational cross-sectional...

Fractional exhaled nitric oxide (FeNO) is a convenient to use biomarker of airway inflammation. However, the mutual relationship between FeNO, peripheral blood eosinophil, total immunoglobulin E (IgE) and inflammatory cytokines showed some controversy.This study was carried out determine accuracy eosinophil IgE detect eosinophilic inflammation as determined by two FeNO cutoff points. The correlation certain also examined.Seventy-six patients with partly controlled asthma performed following...

Background: Recent studies reported a long-lasting effect of COVID-19 infection that extends beyond the active disease and disrupts various body systems besides respiratory system. The current study aims to investigate post-acute SARS-CoV-2 on cardiovascular autonomic activity, reactivity sensitivity in patients who had at least 3 months before. Methods: This was comparative cross-sectional observational study. Fifty-nine subjects were allocated into two groups, controls (n=31), no history...

Composite Autonomic Symptom Score-31 (COMPASS-31) is an easy-to-use screening tool for the evaluation of autonomic dysfunction in various diseases affecting neural function but has rarely been used assessment long coronavirus disease 2019 (COVID-19). This study aimed to evaluate diagnostic accuracy COMPASS-31 score detecting nervous system patients 3 months after COVID-19 infection.

This study aimed to determine the prevalence of migraine in young female adults and identify if a relationship exists between psychological stress or poor sleep quality migraine.This case control was carried out at Imam Abdulrahman Bin Faisal University (IAU), Dammam, KSA from March 2019 2020 on 1,990 students (17- 26-years-old). The tools were Migraine Screening Questionnaire (MS-Q), International Headache Society (IHS) Criteria for Migraine, K10 Psychological Distress Instrument (K10)...

This study aimed to determine the stress levels and identify various factors responsible for causing high-stress scores during COVID-19 pandemic in Saudi population.This cross-sectional was conducted at Imam Abdulrahman Bin Faisal University, Dammam, from June 2020 until December on 4052 respondents Eastern province of Arabia. An online survey used collect information about factors. The psychological impact measured by using event scale (COVID-19 IES), whereas general were assessed K10...

COVID-19 is a public health emergency of international concern. There still no definitive cure for this highly transmittable illness. Immunization and breaking the chain infection only successful approach to mitigate its spread. Our study explored adherence preventive measures associating factors among Health Care Professionals (HCPs) working in Saudi Arabia.For cross-sectional study, an online survey was conducted from December 01, 2020, March 31, 2021, 978 HCPs Arabia. The...

The effect of increasing body weight on pulmonary function and the fractional exhaled nitric oxide (FeNO) remains controversial role different compositions in relationship between obesity with FeNO is still unrevealed. Thus, we aim to determine overweight/obesity lung FeNO, focusing compositions.Eighty-two non-smoker students (20 ± 1.9 years) were divided into two groups: 38 subjects normal (BMI = 18.5-24.99) 44 overweight/obese ≥ 25). Spirometric parameters measured compared groups...

BACKGROUND: Reports indicate that there are menstrual cycle disturbances following coronavirus disease 2019 (COVID-19) vaccination. The present study explored the prevalence of irregularities after COVID-19 vaccination and association with vaccine type, doses, immediate adverse effects, history infection, its severity. MATERIALS AND METHODS: For this cross-sectional study, 406 women reproductive age completed an online survey about postvaccine changes in their menstruation (cycle duration,...

We compared serum leptin levels during various phases of menstrual cycle and its correlation with estradiol between normal weight overweight/obese young females. Fifty-six females were grouped into 26 30 subjects. Serum measured early follicular, pre-ovulatory luteal in both groups using ELISA technique. significantly different across a steady increment from follicular phase (9.97 ± 5.48 ng/dl) through (11.58 6.49 their peaks (12.52 6.39 ng/dl, p < .001). Same pattern change was observed...

Changes in autonomic cardiac activity during night sleep are well documented. However, there is limited information regarding changes the profile daytime naps. Heart rate variability (HRV) and baroreflex sensitivity (BRS) reliable measures of activity. The purpose this study was to determine HRV BRS naps healthy men.This a cross-sectional 25 men. Polysomnographic recording with electrocardiogram monitoring conducted for all volunteers 50-80 min nap between 3.30 pm 5.30 pm. Five-minute...

This study aims to compare the Th1/Th2 cytokines of subjects with general/abdominal obesity and non-obese individuals, correlate them biomarker airways inflammation different body compositions. Eighty were divided into 37 normal weight (BMI >25) 43 overweight/obese groups ≥25). All participants further categorised by waist circumference (WC) an abdominal group (n = 32) a without 48). Serum levels Th1 (INF-γ, TNF-α, IL-2,) Th2 (IL-4, IL-5, IL-13) measured using multiplex ELISA technique. The...

<ns4:p>Nigella sativa (<ns4:italic>N. sativa</ns4:italic>) is traditionally used as an immune enhancer in different communities. The aim of this study was to evaluate the effect <ns4:italic>N. sativa</ns4:italic> on immunity related parameters young healthy subjects. This a double blind, randomized, placebo controlled clinical trial. Fifty-two subjects (48 male and 4 female) 18-25 years old were enrolled study. They randomly divided into four groups; first received charcoal capsules served...

A reliable, migraine-specific biomarker has not been identified so far. Calcitonin Gene-Related Peptide (CGRP) and Apolipoprotein E (ApoE) might serve as migraine biomarkers due to their roles in pathophysiology. However, diagnostic usefulness explored yet. Present study the accuracy of CGRP ApoE migraine.A cross-sectional, case-control was conducted from November 2019 April 2020 at Physiology department our university. Fourteen female patients, 18-25 years old, with confirmed "Migraine"...

To compare serum adiponectin changes across the menstrual cycle between normal weight and overweight/obese young women its correlation with estradiol. Young (n=56) regular had been grouped according to their BMI into group (n=26) overweight /obese (n=30). Blood samples were drawn during early follicular (FP), pre-ovulatory (OP) luteal phases (LP) of for estradiol levels determination using enzyme-linked immunosorbent assay. Adiponectin level showed a significant decreasing pattern in group....

The cyclical changes of hormones during the menstrual cycle are responsible not only for reproductive function but also have other effects on dietary intake and appetite. current study aimed to investigate variations appetite-related (ghrelin obestatin) their association with adipokines, estrogen, BMI.Fifty-six regularly menstruating female students were grouped into normal weight (BMI ≤24.9; n = 26), overweight/obese subjects ≥25; 30). Serum ghrelin, obestatin, leptin, adiponectin, estrogen...

We analyzed the association between kisspeptin and plasma adipokines (leptin adiponectin) in normal-weight over-weight young females. Thirty Saudi females, based on their body mass index (BMI), were divided into two groups (15 students/group) as (1) Normal weight (NW): BMI = 18.5–24.99 (2) Over-weight/obese (OW): ≥ 25. Serum (leptin, levels measured early follicular, pre-ovulatory, luteal phase both with ELISA. Menstrual cycle phases confirmed by serum estradiol levels. There was no of...

In this study, we aimed to assess the maximal oxygen uptake (VO

Migraine is a genetic disorder characterized by recurrent episodes of headache that are throbbing in nature. The objective this study was to directly compare the efficacy and safety anti-calcitonin gene-related peptide (anti-CGRP) botulinum neurotoxin (BoNT) for preventive treatment chronic migraine.