A5074368253- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Genetic factors in colorectal cancer
- Diagnosis and treatment of tuberculosis
- Gallbladder and Bile Duct Disorders
- Appendicitis Diagnosis and Management
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Hemoglobinopathies and Related Disorders
- Clinical Nutrition and Gastroenterology
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal motility and disorders
- Gut microbiota and health
- Intraperitoneal and Appendiceal Malignancies
- Diet and metabolism studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Iron Metabolism and Disorders
- Liver Disease and Transplantation
- Diverticular Disease and Complications
- Autoimmune and Inflammatory Disorders
Imam Abdulrahman Bin Faisal University
2010-2025
King Fahd Hospital of the University
2008-2025
Creative Commons
2012-2014
Health Affairs
2014
King Fahad Specialist Hospital
2012
King Khalid University Hospital
1997-2012
Dammam Central Hospital
2012
King Faisal University
1994-2010
King Saud University
1997
Background/Aim: A large number of diseases are ascribed to Helicobacter pylori (H. pylori), particularly chronic active gastritis, peptic ulcer disease and gastric cancer. Successful treatment H. infection with antimicrobial agents can lead regression pylori–associated disorders. Antibiotic resistance against is increasing, it necessary find new effective agents. Nigella sativa seed (NS), a commonly used herb, possesses in vitro anti-helicobacter activity. The present study was undertaken...
Pediatric inflammatory bowel disease (IBD) is increasingly recognized in developing countries; however, the incidence and trend over time have not been reported. This retrospective study included children diagnosed with IBD gastroenterology centers Kingdom of Saudi Arabia between 2003 2012. The date birth, age at diagnosis, gender, final diagnosis were collected on special forms. Clinical, laboratory, imaging, endoscopy, histopathology results reviewed to confirm diagnosis. Descriptive...
The role of schistosomes in the pathologenesis acute appendicitis an endemic area was investigated. Of 1600 appendicectomies received our laboratory, 26 showed appendiceal schistosomiasis, which prompted what we believe to be first detailed histopathological evaluation all appendices with schistosomal infestation, without prior knowledge clinical and operative diagnoses. results suggest that there are two types appendicitis, each distinct clinicopathological features different pathogenetic...
Abstract Background Crohn’s diseases and ulcerative colitis, both of which are chronic immune-mediated disorders the gastrointestinal tract major contributors to overarching Inflammatory bowel diseases. It has become increasingly evident that pathological processes IBDs results from interactions between genetic environmental factors, can skew immune responses against normal intestinal flora. Methods The aim this study is assess analyze taxa diversity relative abundances in CD UC Saudi...
Background: Trials on functional dyspepsia (FD) have been performed mostly in Western populations. We evaluated the effect of cisapride Saudi Arabs with FD. Methods: In a double-blind, randomized, placebo-controlled trial patients were treated three times daily or matching placebo and assessed at 2 4 weeks. Results: Cisapride (n = 44) was significantly superior to 45) improving heartburn, postprandial bloating, epigastric pain, early satiety, burning, nausea. The global response treatment...
Introduction In this article, we report 7 novel KRAS gene mutations discovered while retrospectively studying the prevalence and pattern of in cancerous tissue obtained from 56 Saudi sporadic colorectal cancer patients Eastern Province. Methods Genomic DNA was extracted formalin-fixed, paraffin-embedded noncancerous tissues. Successful specific PCR products were then bi-directionally sequenced to detect exon 4 Mutector II Detection Kits used for identifying codons 12, 13 61. The functional...
Background: The obesity epidemic, which is among the most common nutritional disorders, rising rapidly worldwide. It leads to several health problems such as metabolic stroke, and even cancer. Efforts control with exercise diet have a limited value in obese patients different approaches do this been tried. In paper, we share our experience bioenteric intragastric balloon (BIB) treating obesity: Its safety, tolerability, its efficacy weight reduction. Materials Methods: From January 2009...
Large-scale gut microbiome sequencing has revealed key links between dysfunction and metabolic diseases such as type 2 diabetes (T2D). To date, these efforts have largely focused on Western populations, with few studies assessing T2D microbiota associations in Middle Eastern communities where prevalence is now over 20%. We analyzed the composition of stool 16S rRNA from 461 119 non-T2D participants Province Saudi Arabia. quantified abundance microbial to examine any significant differences...
Plasma zinc and copper concentrations were determined by atomic absorption spectroscopy in 57 patients with sickle cell anemia 45 control subjects from the Eastern Province of Saudi Arabia. levels found to be close those subjects. Similarly, there was a difference neither urinary level nor ratio Cu:Zn This is contrast situation which exists North American Black anemia, who are known have deficiency as well further decrease during crises. The near-normaLlevels therefore exclude confirm that...
Handlebar hernias are abdominal wall resulting from direct trauma to the anterior wall. They usually result at weak anatomic locations of Such traumatic rare, requiring a high index suspicion for clinical diagnosis. We report case handlebar hernia an injury sustained during vehicular injury, and discuss management such injuries.
Background/Aims: Metabolic bone disease is common in patients with inflammatory bowel (IBD). Our aim was to determine the frequency of loss among Saudi IBD and possible contributing risk factors. Settings Design: We retrospectively reviewed IBD, between 18 70 years age, who had mass density (BMD) determined by dual-energy X-ray absorptiometry scanning at one three hospitals Kingdom Arabia from 2001 2008. Patients Methods: Case notes BMDs results were carefully for demographic clinical data....
An increased level of interleukin-17A and interleukin-18 in the serum intestinal mucosa celiac disease patients reflecting severity villous atrophy inflammation was documented. Thus, objective this study to evaluate concentrations salivary-17A, interleukin-1 beta, with who are on a gluten-free diet, both without periodontitis, compare these levels those healthy individuals.
Although the role of fungi in gut inflammation IBD has been suggested, data are still limited ulcerative colitis (UC). Our aim was to describe fungal profile a pediatric UC Saudi Arabia.
The prevalence of gastroesophageal reflux disease (GERD) in chronic renal failure patients and transplant recipients (RTR) has been a subject discussion the last few years. Our aims are to clarify this association its relation Helicobacter pylori infection, also identify possible pathogenic factors development both groups.The study involved 40 end-stage (ESRD) with upper gastrointestinal (GI) symptoms (group I), 36 who had undergone kidney transplantation similar II), 44 age- sex-matched...
A 3 1/2-month-old male infant presented with hematemesis due to erosive gastritis following whole-cow's-milk feeding. The presence of eosinophilic gastritis, the disappearance symptoms after withdrawal feeding, and association facial eczema suggest that was induced by cow's milk. Cow's-milk intolerance should be considered in etiologic differential diagnosis infancy.
Abdominal tuberculosis is not uncommon in developing countries (1-3) and still found developed countries, particularly among immigrants (4-6). In general, it can occur as either tuberculous peritonitis or gastrointestinal tuberculosis, but both manifestations may coexist the same patient. It present acute obstruction perforation, simulating appendicitis, peritonitis, enterocolitis, intersusception (7-9). Early diagnosis children be difficult, largely because of variable vague symptoms...