Clifford M. Chang

ORCID: 0000-0003-0573-1569
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About
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Research Areas
  • Salivary Gland Tumors Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Vascular Tumors and Angiosarcomas
  • Cardiac tumors and thrombi
  • Cancer Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • Thyroid Cancer Diagnosis and Treatment
  • Phytoplasmas and Hemiptera pathogens
  • Cancer Genomics and Diagnostics
  • Viral-associated cancers and disorders
  • Head and Neck Anomalies
  • Head and Neck Surgical Oncology
  • Tumors and Oncological Cases
  • Sarcoma Diagnosis and Treatment
  • Rabies epidemiology and control
  • Cancer Cells and Metastasis
  • Biochemical Analysis and Sensing Techniques
  • RNA modifications and cancer
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Microbial infections and disease research
  • Thyroid and Parathyroid Surgery
  • Carbohydrate Chemistry and Synthesis
  • Lung Cancer Diagnosis and Treatment
  • Glycosylation and Glycoproteins Research
  • Virology and Viral Diseases

Health Net
2024

Inspira Medical Center Vineland
2024

University of Michigan
2020-2024

New York University
2012-2022

NYU Langone Health
2020

Abstract Background Small cohort studies have suggested oral tongue squamous cell carcinoma (OTSCC) could be associated with worse prognosis in individuals younger than 40. Methods We compared the survival of all OTSCC cases National Cancer Database under 40 years old those older 40, excluding patients over 70. Cox regression and propensity score matched (PSM) analyses were performed. Results A total 22 930 identified. The group consisted 2566 (9.9%) cases; 20664 to 70 (90.1%). Most male (13...

10.1002/hed.25772 article EN Head & Neck 2019-04-15

Objective To analyze the patterns of care and survival cutaneous angiosarcomas head neck. Study Design Retrospective cohort study. Setting National Cancer Database. Methods The Database was queried to select patients with angiosarcoma neck between 2004 2015. For analysis, were included only if they received definitive treatment complete data. Prognostic factors analyzed by univariate multivariable Cox regression. Results We identified 693 diagnosed during study period. majority male (n =...

10.1177/0194599820905495 article EN Otolaryngology 2020-02-11

Tetrapodal receptor 1 relies upon structural flexibility to reveal new binding modes for saccharide recognition and achieve unique pyranoside affinity concentration dependent selectivity. The association constants, Kas, between eight pyranosides commonly found in cell surface glycans were measured CDCl3 by 1H NMR titrations, revealing a preference α- β-octyl mannopyranosides (α-Man β-Man). Whereas most of the studied – α/β-octyl glucopyranoside (α/β-Glc), galactopyranoside (α/β-Gal),...

10.1039/c2sc20873c article EN Chemical Science 2012-09-27

Clear cell carcinoma (CCC) is a rare salivary gland malignancy, believed to be generally low grade. We investigated CCC epidemiology and clinical behavior, using the National Cancer Database (NCDB).Retrospective cohort study.NCDB.All CCCs of glands were selected between 2004 2015. Patient demographics, tumor characteristics, treatments, survival analyzed. Cox regression analyses performed in treated patients.We identified 268 patients with CCC. Median age was 61 (21-90) years. Most female...

10.1177/0194599819835779 article EN Otolaryngology 2019-03-12

The role of surgery for conventionally "unresectable" (cT4b) oral cavity squamous cell carcinoma is unclear. We analyzed factors associated with overall survival in cT4b relative to cT4a carcinoma.We identified 6830 and 522 chemoradiation or + adjuvant therapy patients the National Cancer Data Base from 2004 2016. main outcome was survival. Statistical analysis performed using chi-squared tests, univariable multivariable regression analysis.The group had a higher rate positive margins (30.4%...

10.1177/00034894211038213 article EN Annals of Otology Rhinology & Laryngology 2021-08-07

Introduction: Capnocytophaga ochracea is found in the human oral microbiome and a rare cause of antibiotic-resistant, opportunistic septicemia immunocompromised hosts. The zoonotic transmission C from canines to humans has not yet been reported literature. Cohabitation with people associated colonization dogs may be reservoir for infections, which have decreased susceptibility first-line antibiotics commonly used treat animal exposures. Case Report: This case 70-year-old male remote history...

10.5811/cpcem.5826 article EN cc-by Clinical Practice and Cases in Emergency Medicine 2024-07-11

Abstract Background: The updated American Joint Committee on Cancer (AJCC) 8th Edition staging manual restructured nodal classification and by placing less prognostic emphasis metastases for human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC). However, there was no change HPV-negative OPSCC. purpose of our study is to examine the impact survival in Methods: OPSCC queried from National Database (NCDB) Surveillance, Epidemiology End Results program (SEER)...

10.1158/1055-9965.epi-21-0776 article EN Cancer Epidemiology Biomarkers & Prevention 2022-05-17

Abstract Despite advances in treatment modalities for head and neck squamous cell carcinoma (HNSCC) survival rates remain unchanged. Tumor heterogeneity within HNSCC as well the tumor microenvironment (TME) has been shown to be a major driver of failure poor outcomes. A key component TME potential deciphering are cancer stem cells. While numerous studies have demonstrated tumorigenicity malignant these cells, few investigated their expression profiles. The aim this study is leverage single...

10.1158/1538-7445.tumhet2020-po-006 article EN Cancer Research 2020-11-01
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