- Pharmaceutical Practices and Patient Outcomes
- Emergency and Acute Care Studies
- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Patient Safety and Medication Errors
- Healthcare Technology and Patient Monitoring
- Electrolyte and hormonal disorders
- Frailty in Older Adults
- Potassium and Related Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Sepsis Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Heart Failure Treatment and Management
- Electronic Health Records Systems
Laurentius Ziekenhuis
2023-2024
Erasmus University Rotterdam
2023
Zuyderland Medisch Centrum
2022-2023
Erasmus MC
2022-2023
Maastricht University Medical Centre
2018-2022
General Department of Preventive Medicine
2017
Background Polypharmacy in older patients can lead to potentially inappropriate prescribing. The risk of the latter calls for effective medication review ensure proper usage and safety. Objective Provide insight on similarities differences done multiple ways that may future possibilities optimize review. Setting This study was conducted Zuyderland Medical Centre, second largest teaching hospital Netherlands. Method descriptive compares quantity content remarks identified by performed a...
Abstract Background Due to ageing of the population incidence multimorbidity and polypharmacy is rising. Polypharmacy a risk factor for medication-related (re)admission therefore places significant burden on healthcare system. The reported (re)admissions varies widely due lack clear definition. Some medications are known increase admission published in triggerlist Dutch guideline older patients. Different interventions support medication optimization have been studied reduce (re)admissions....
Inappropriate prescribing is associated with negative patient outcomes. In hospitalized patients, the use of Clinical Decision Support Systems (CDSSs) may reduce inappropriate and thereby improve patient-related However, recently published large clinical trials (OPERAM SENATOR) have shown results on CDSSs outcomes strikingly low acceptance recommendations.The purpose present study was to investigate a CDSS in real-life setting older patients. As such, we report pattern this in-hospital...
Abstract Background The prevalence of medication-related emergency department visits and acute hospital admissions in older patients is rising due to the ageing population increasing multimorbidity associated polypharmacy. Aim To explore whether a combined medication review performed outpatient setting reduces number (re)admissions. Method All consecutive visiting geriatric clinic underwent multifaceted (i.e. evaluation by at least geriatrician, and/or pharmacist use clinical decision...
Hyponatremia is a common finding in hospitalized patients. In this retrospective cohort study we assessed the characteristics and outcome of acute medical admissions with hyponatremia. Compared to normal sodium group, those hyponatremia were significantly older Charlson Comorbidity Index (CCI) was higher. The number MCU/ICU between both groups similar, but hyponatremic patients had longer length stay 28-day one-year mortality higher, even mild independently associated after adjustment for...
The aims of this retrospective cohort study were to retrieve characteristics and outcomes older (65+) medical patients who are directly admitted ICU from the ED compare these with those a ward. Of 1396 patients, 21 (1.5%) 54 (3.9%) after delay. Blood pressure was lower respiratory rate higher in direct than delayed group. group had mortality (28-day: 19.0 vs. 38.9%, p=0.14; 1-year: 42.9 66.7%; p=0.06), shorter length-of-stay returned more frequently independent living Only fraction ICU; tend...
Abstract Background Drug-related problems (DRPs) and potentially inappropriate prescribing (PIP) are associated with adverse patient health care outcomes. In the setting of hospitalized older patients, Clinical Decision Support Systems (CDSSs) could reduce PIP therefore improve clinical However, prior research showed a low proportion adherence to CDSS recommendations by clinicians possible explanatory factors such as little relevance alert fatigue. Objective To investigate use in real-life...
Abstract Background. The prevalence of medication related emergency department visit and acute hospital admission is significant in older patients due to the high multimorbidity associated polypharmacy. Aim. To explore whether a multifaceted outpatient review could alter overall an admission. Method. All new visiting our geriatric clinic had (evaluation by geriatrician, pharmacist clinical decision support system). Subsequently we analysed number reason for visit, readmission year prior...