A5079449454- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Diabetes and associated disorders
- Phytochemicals and Antioxidant Activities
- Eicosanoids and Hypertension Pharmacology
- Edible Oils Quality and Analysis
- Skin Protection and Aging
- Alcohol Consumption and Health Effects
- Dietary Effects on Health
- Inflammasome and immune disorders
- Lipoproteins and Cardiovascular Health
- Cancer, Stress, Anesthesia, and Immune Response
- Stress Responses and Cortisol
- Cholesterol and Lipid Metabolism
- Polysaccharides and Plant Cell Walls
- Biological Activity of Diterpenoids and Biflavonoids
- Pomegranate: compositions and health benefits
- Plant biochemistry and biosynthesis
- Natural Compound Pharmacology Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Liver Disease Diagnosis and Treatment
University of Salerno
2020-2022
University of Naples Federico II
2018
Abstract Background Understanding how HLA polymorphisms may affect both susceptibility, course and severity of Covid-19 infection could help at the clinical level to identify individuals higher risk from disease epidemiological one explain differences in epidemic trend among countries or even within a specific country. Italy showed peculiar geographical distribution northern most affected regions southern ones only slightly touched. Methods In this study we analysed regional frequencies for...
The fruit of Garcinia mangostana (mangosteen) is known in ancient traditional Asian medicine for its antioxidant, anti-inflammatory, immunomodulatory and anticancer activities. These effects are mainly due to the action polyphenols as xanthones, which contained pericarp fruit. In recent years, there has been a growing interest from pharmaceutical companies formulating new topicals based on mangosteen full extracts prevent skin aging. However, molecules responsible these mechanisms involved...
Cardiovascular diseases, followed by strokes, represent the leading cause of mortality worldwide. Despite its success in preventing cardiovascular therapeutic potential 3-Hydroxytyrosol (HT) for treating ischemic diseases is yet to be investigated detail, especially with regard heart disease, which a major challenge humans. We assessed that low concentrations (1–5 µM) HT, generally achieved after ingestion olive oil, stimulate endothelial cells migration and angiogenesis an vitro model. At...
3-hydroxytyrosol (HT) is the main phenolic compound found in olive oil with known antioxidant, anti-inflammatory, and antimicrobial properties several dermatological conditions, both when taken form of or pure cosmeceutical formulations. To date, its direct effect on wound healing process molecular mechanisms involved have not yet been elucidated. Thus, present study, we aimed to explore effects vitro epidermal keratinocyte cultures focusing mechanism implied. HT was able induce...
To date stress, a highly complex process that disrupts homeostasis and involves environmental psychosocial factors, is considered as one of the most crucial factor affects our daily life, especially urban dweller's life.
Abstract Background: Understanding how HLA polymorphisms may affect both susceptibility, course and severity of Covid-19 infection could help at the clinical level to identify individuals higher risk from disease epidemiological one explain differences in epidemic trend among countries or even within a specific country. Italy showed peculiar geographical distribution northern most affected regions southern ones only slightly touched. Methods: In this study we analysed regional frequencies...
Mevalonate kinase deficiency (MKD) is a rare autoinflammatory genetic disorder characterized by recurrent fever attacks and systemic inflammation with potentially severe complications. Although it recognized that the lack of protein prenylation consequent to mevalonate pathway blockade drives IL1β hypersecretion, hence autoinflammation, MKD pathogenesis molecular mechanisms underlaying most its clinical manifestations are still largely unknown. In this study, we performed comprehensive...