Lili Chen

ORCID: 0000-0003-0612-9422
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About
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Research Areas
  • Clinical Nutrition and Gastroenterology
  • Nutrition and Health in Aging
  • Dementia and Cognitive Impairment Research
  • Salivary Gland Disorders and Functions
  • Liver physiology and pathology
  • Cancer, Hypoxia, and Metabolism
  • Estrogen and related hormone effects
  • Biochemical and Molecular Research
  • Diet and metabolism studies
  • Art Therapy and Mental Health
  • RNA modifications and cancer
  • Nutrition, Health and Food Behavior
  • Cell Adhesion Molecules Research
  • Health and Wellbeing Research
  • Cancer-related gene regulation
  • Dysphagia Assessment and Management
  • Child Nutrition and Feeding Issues
  • Attention Deficit Hyperactivity Disorder
  • COVID-19 and Mental Health
  • Long-Term Effects of COVID-19
  • Mechanisms of cancer metastasis
  • Music Therapy and Health
  • RNA Research and Splicing
  • Oral microbiology and periodontitis research
  • Gut microbiota and health

Fujian Medical University
2015-2025

Fujian Provincial Hospital
2015-2025

Fuzhou University
2025

Capital Medical University
2023

Abstract Background Intensive care unit-acquired weakness (ICU-AW) is a prevalent and severe issue among ICU patients. Resistance training beta-hydroxy-beta-methylbutyrate (HMB) intervention have demonstrated the potential to enhance muscle function in patients with sarcopenia older adults. The purpose of this study was determine whether resistance and/or HMB administration would improve physical function, strength, quality life medical Methods In multicentre, four-arm, single-blind...

10.1186/s13054-023-04698-x article EN cc-by Critical Care 2023-12-15

This study aimed to investigate the effects of a feeding intervention in patients with Alzheimer's disease dysphagia.In disease, inadequate food and fluid intake can result malnutrition, dehydration increased morbidity mortality. Patients may lose self-care abilities such as self-feeding.A prospective cohort study.A three-month self-control was conducted prospectively 30 nursing home residents dysphagia. Pre- post-intervention measures included Kubota water swallow test, type amount...

10.1111/jocn.13013 article EN Journal of Clinical Nursing 2015-09-30

Abstract Background Art-based interventions may delay cognitive decline and improve health-related outcomes in older adults with mild impairment (MCI). Objective To examine the effects of Creative Expressive Arts-based Storytelling (CrEAS) program compared to active waitlist controls on neurocognitive other people MCI. Design Three-arm parallel-group, randomised controlled design. Participants One-hundred thirty-five MCI (mean age: 70.93 ± 6.91 years). Methods were randomly assigned...

10.1093/ageing/afac144 article EN Age and Ageing 2022-07-01

Abstract Aim To examine association between subgingival microbial signatures and levels of cognitive impairment in older adults. Materials Methods We analysed plaque samples 16S ribosomal RNA sequences for microbiota among 165 participants (normal controls [NCs]: 40, subjective decline [SCD]: mild [MCI]: 49 dementia: 36). Results The bacterial richness was lower individuals with worse function, communities differed significantly the four groups. Declining function associated decreasing...

10.1111/jcpe.13997 article EN Journal Of Clinical Periodontology 2024-05-20

PGC-1α and ERRα are closely related to tumor formation progression. However, the mechanism underlying involvement of PGC-1α/ERRα in regulating invasion migration endometrial cancer remains be explored.Elevated levels were associated with advanced myometrial invasion, Vimentin expression was depth premenopausal cancer. Silencing reduced activation inhibited epithelial-mesenchymal-transition phenotypes, resulting significant inhibition migration. Overexpression led enhanced increased activity...

10.18632/aging.103611 article EN cc-by Aging 2020-09-13

We aim to investigate whether a popular hand exercise could be used improve the action of eating in patients with Alzheimer's disease (AD). A 6-month intervention was conducted 60 AD who live nursing home. They were divided into and control groups. Patients group maintained their daily routine. The improvement Edinburgh Feeding Evaluation Dementia scale significantly greater than ( P = .003). Significant differences time autonomous simulated between groups < .05) noted. improvements accuracy...

10.1177/1533317518803722 article EN American Journal of Alzheimer s Disease & Other Dementias® 2018-10-09

// Pengming Sun 1, 2 , Lifang Xue Yiyi Song Xiaodan Mao 1 Lili Chen Binhua Dong Elena Loana Braicu 3 and Jalid Sehouli Laboratory of Gynecologic Oncology, Fujian Provincial Maternity Children Hospital, Affiliate Hospital Medical University, 350001 Fuzhou, Fujian, P.R. China Department Gynecology, Oncology Charité, Campus Virchow-Klinikum, European Competence Center for Ovarian Cancer University Berlin, 13353 Germany Correspondence to: Sun, email: sunfemy@hotmail.com Keywords: matriptase;...

10.18632/oncotarget.23913 article EN Oncotarget 2018-01-03

Abstract Background: Cytidine nucleotide triphosphate synthase 1 (CTPS1) is a CTP which play critical roles in DNA synthesis. However, its biological regulation and mechanism triple-negative breast cancer (TNBC) has never been reported yet. Methods: The expression of CTPS1 TNBC tissues was determined by GEO, TCGA databases immunohistochemistry (IHC). effect on cell proliferation, migration, invasion, apoptosis tumorigenesis were explored vivo vitro. In addition, the transcription factor...

10.21203/rs.3.rs-862590/v1 preprint EN cc-by Research Square (Research Square) 2021-09-20
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