A5035611362- Acupuncture Treatment Research Studies
- Epigenetics and DNA Methylation
- Intensive Care Unit Cognitive Disorders
- Psychosomatic Disorders and Their Treatments
- Prostate Cancer Treatment and Research
- Cancer, Hypoxia, and Metabolism
- Mitochondrial Function and Pathology
- Ferroptosis and cancer prognosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Frailty in Older Adults
- Clinical Nutrition and Gastroenterology
- Biofield Effects and Biophysics
- Renal and related cancers
- Cardiac Arrest and Resuscitation
- Renal cell carcinoma treatment
- Diet and metabolism studies
- Nutrition and Health in Aging
- Bone Metabolism and Diseases
- Neurological Disorders and Treatments
- Advanced Neuroimaging Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- Liver physiology and pathology
- Smoking Behavior and Cessation
- Traumatic Brain Injury Research
- Cardiovascular Health and Risk Factors
Second Affiliated Hospital of Fujian Medical University
2023-2025
Fujian Medical University
2023-2025
Mianyang Third People's Hospital
2024
Nanchang University
2020-2023
Zhongnan Hospital of Wuhan University
2023
Wuhan University
2020-2023
First Affiliated Hospital of Nanchang University
2020-2023
Shenzhen Nanshan Center for Chronic Disease Control
2023
Sichuan University
2022
West China Hospital of Sichuan University
2022
PURPOSE: To characterize the central nervous system (CNS) pathway for acupuncture stimulation in human brain by using functional magnetic resonance (MR) imaging. MATERIALS AND METHODS: Functional MR imaging of whole was performed two groups nine healthy subjects during four paradigms: real at acupoints ST.36 (on leg) and LI.4 hand) control stimulations (minimal superficial pricking on leg). Stimulations were semirandomized, balanced order nested within experiments. Psychophysical responses...
Abstract Background Intensive care unit-acquired weakness (ICU-AW) is a prevalent and severe issue among ICU patients. Resistance training beta-hydroxy-beta-methylbutyrate (HMB) intervention have demonstrated the potential to enhance muscle function in patients with sarcopenia older adults. The purpose of this study was determine whether resistance and/or HMB administration would improve physical function, strength, quality life medical Methods In multicentre, four-arm, single-blind...
Abstract The patient–acupuncturist interaction was a critical influencing factor for acupuncture effects but its mechanism remains unclear. This study aimed to examine the inter‐brain of dyad during stimulation in naturalistic clinical setting. Seventy healthy subjects (simulated “patients”) were randomly assigned two groups and received verum group or sham by one acupuncturist. Functional near‐infrared spectroscopy hyperscanning used simultaneously record neural responses...
Purpose: Previous studies in patients with Alzheimer's disease have shown amyloid beta accumulation the brain and abnormal activity, mild cognitive impairment (MCI) early stages of disease. The aim current study was to investigate functional connectivity MCI. Methods: We recruited 24 subjects total, including 12 MCI (6 men 6 women) healthy controls (HCs) women), matched for age, gender, lifestyle factors. All underwent resting-state magnetic resonance imaging scans voxel-wise degree...
Abstract Background WD repeat domain 3 (WDR3) is involved in tumor growth and proliferation, but its role the pathological mechanism of prostate cancer (PCa) still unclear. Methods WDR3 gene expression levels were obtained by analyzing databases our clinical specimens. The genes proteins determined a real‐time polymerase chain reaction, western blotting immunohistochemistry, respectively. Cell‐counting kit‐8 assays used to measure proliferation PCa cells. Cell transfection was investigate...
Objective: T cell-mediated injury plays an important role in the pathogenesis of autoimmune premature ovarian insufficiency (POI). The purpose this study was to assess percentage CD4+CD25+FOXP3+ regulatory (Treg) cells and level forkhead box protein 3 (FOXP3) mRNA expression POI patients.Methods: case–control compared 30 patients with healthy subjects. Peripheral blood mononuclear were collected. Treg measured by flow cytometry using specific monoclonal antibodies recognizing CD4+, CD25+,...
<b><i>Background/Aims: </i></b>Lipoprotein glomerulopathy (LPG) is a rare hereditary disease. In this study, we investigated the apoE mutation and role of double filtration plasmapheresis therapy (DFPP) on new Chinese patient with LPG. <b><i>Methods: </i></b>Renal biopsy was performed to allow definitive diagnosis. The mutations in coding sequence pedigree were by DNA sequencing. treated DFPP, clinical parameters before after DFPP compared....
Acupuncture is a promising non-pharmacological therapy for patients with prolonged disorder of consciousness (PDOC); however, its underlying mechanism remains uncertain. This study aimed to reveal the modulatory effects acupuncture on cerebral cortex activity among PDOC.Twenty-eight PDOC were randomly assigned treatment (n = 14) or control group. The group received one session acupuncture, while sham acupuncture. All underwent evaluation functional connectivity and activation response...
Hypoxia is an essential hallmark of solid tumors and HIF1α a central regulator tumor cell adaptation survival in the hypoxic environment. In this study, we explored biological functions cycle division-related gene 8 (CDCA8) bladder cancer (BCa) cells settings. Specifically, found that CDCA8 was significantly upregulated BCa lines clinical samples its expression positively correlated with advanced stage, grade, poor overall (OS). The proteins required for to survive condition....
Abstract Background Numerous studies have shown that local therapy can improve long-term survival in patients with metastatic prostate cancer. However, it is unclear which are the potential beneficiaries. Methods We obtained information on cancer from Surveillance, Epidemiology, and End Results database divided eligible into treatment group non-local group. Propensity score matching (PSM) was used to reduce influence of confounding factors. In matched (LT) group, if median overall time (OS)...
Mitochondrial metabolic reprogramming (MMR)-mediated immunogenic cell death (ICD) is closely related to the tumor microenvironment (TME). Our purpose was reveal TME characteristics of clear renal carcinoma (ccRCC) by using them.Target genes were obtained intersecting ccRCC differentially expressed (DEGs, VS normal) with MMR and ICD-related genes. For risk model, univariate COX regression K-M survival analysis used identify most associated overall (OS). Differences in TME, function,...
<b><i>Background/Aims: </i></b>Autosomal-dominant polycystic kidney disease (ADPKD), a heterogeneous genetic disorder characterized by massive enlargement and progressive chronic disease, is due to abnormal proliferation of renal tubular epithelium. ADPKD known be caused mutations in PKD1 PKD2 genes. <b><i>Methods: </i></b>In the present study, mutation analysis PKD genes was performed new Chinese family with using Long-Range (LR) PCR...
The aim of this study was to investigate the influence enhanced external counterpulsation (EECP) on cardiac function beagle dogs after prolonged ventricular fibrillation. Twenty-four adult male beagles were randomly divided into control and EECP groups. Ventricular fibrillation induced in animals for 12 min, followed by 2 min cardiopulmonary resuscitation. They then received therapy 4 h (EECP group) or not (control group). hemodynamics monitored using PiCCO2 system. Blood gas hemorheology...
<title>Abstract</title> <bold>Purpose:</bold>This study aims to assess the impact of dietary factors on osteoporosis prevalence within a natural population in Sichuan, China, establish foundation for future intervention strategies. <bold>Methods</bold>: Participants were drawn from prospective cohort centered selecting representative sites and employing cluster random sampling execute projects across various locations Southwestern China. This approach enabled collection data populations with...
Abstract Background Intensive care unit–acquired weakness (ICU‐AW) is prevalent and adversely affects patient outcomes. Muscle strength progression response to rehabilitation differ across ICU populations. However, the trajectories, determinants prognoses of muscle changes remain unclear. Aim This study aimed investigate trajectory ICU‐AW in critical illness its impact on 60‐day postadmission mortality. Study design A multicentre prospective cohort was conducted, involving critically ill...
Objective To evaluate the efficacy and long-term safety of autologous bone marrow stem cells (ABMSC) transplantation in patients with hepatitis B virus(HBV)-associated decompensated liver cirrhosis. Methods This was an open-label, prospective matched case-control study. Thirty HBV-associated cirrhosis hospitalized at Third Affiliated Hospital Sun Yat-Sen University from January 2005 to June 2010 were collected infused (stem cell group). Another thirty control group according baseline...