A5100621209- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Acute Ischemic Stroke Management
- Liver Disease and Transplantation
- Blood Pressure and Hypertension Studies
- Lipid metabolism and disorders
- Healthcare and Venom Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neurofibromatosis and Schwannoma Cases
- Cardiovascular Health and Disease Prevention
- Organ Transplantation Techniques and Outcomes
- Cancer, Hypoxia, and Metabolism
- Diet, Metabolism, and Disease
- Venous Thromboembolism Diagnosis and Management
- Congenital Heart Disease Studies
- Meningioma and schwannoma management
- Natural Antidiabetic Agents Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Traditional Chinese Medicine Studies
- Neurological Disease Mechanisms and Treatments
- Liver physiology and pathology
- Diet and metabolism studies
- Tuberculosis Research and Epidemiology
- Acute Myeloid Leukemia Research
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2025
Peking University Third Hospital
2002-2025
Peking University
2002-2025
Zhejiang Normal University
2025
Jinan Central Hospital
2025
Soochow University
2014-2025
Tianjin Medical University General Hospital
2015-2025
Beijing Anding Hospital
2024
University of South Australia
2024
Nanjing Medical University
2011-2024
Abstract Objectives To estimate the burden, trends, and inequalities of type 1 diabetes mellitus (T1DM) among older adults at global, regional, national level from 1990 to 2019. Design Population based study. Adults aged ≥65 years 21 regions 204 countries territories (Global Burden Disease Risk Factors Study 2019) Main outcome measures Primary outcomes were T1DM related age standardised prevalence, mortality, disability adjusted life (DALYs), average annual percentage change. Results The...
Background Characterizing and assessing the prevalence, awareness, treatment patterns of patients with isolated diastolic hypertension ( IDH ) can generate new knowledge highlight opportunities to improve their care. Methods Results We used data from China PEACE (Patient‐centered Evaluative Assessment Cardiac Events) Million Persons Project, which screened 2 351 035 participants aged 35 75 years between 2014 2018. was defined as systolic blood pressure <140 ≥90 mm Hg; awareness...
To investigate the effects of probiotics on liver function, glucose and lipids metabolism, hepatic fatty deposition in patients with non-alcoholic disease (NAFLD).Totally 140 NAFLD cases diagnosed our hospital from March 2017 to 2019 were randomly divided into observation group control group, 70 each. The received diet exercise therapy, while oral based intervention 2 groups lasted for 3 months. indexes activity score (NAS), conditions fecal flora compared before after treatment.Before...
Stroke is one of the leading causes mortality and morbidity vascular diseases, its incidence maintains at a high level around world. In China, stroke has been major public health problem. Because pathogenesis ischemic different from that hemorrhagic stroke, their clinical factors would not be same. Therefore to investigate effects various effect on versus then enhance prevention are crucial decrease incidence.A total 692 patients, consisting 540 patients 152 East were included in this study....
Background Globally, Diabetic Retinopathy (DR) is a leading cause of vision loss. This disease, which impacts the microvasculature retina, brought on by oxidative stress linked to diabetes. Several studies have shown anti-diabetic properties plant-derived phytochemical "Berberine". However, there limited amount research available its effects, specifically (DR). Objectives The primary aim present investigation assess impact berberine DR in rats examining underlying influence stress,...
Abstract Background The burden of dementia is increasing dramatically with the population aging. Tinnitus and chronic noise exposure are associated neuropsychiatric diseases cognitive decline, but relationships between tinnitus incident remain unclear. Methods 160 032 participants from UK Biobank were included. Information on tinnitus, severity, (loud music noisy workplace) was collected at baseline. Cox proportional hazards models used to assess associations severity risk dementia. Logistic...
Abstract Introduction Intermittent hypoxia (IH) is a hallmark manifestation of obstructive sleep apnea (OSA), prevalent breathing disorder. IH causes central nervous system (CNS) inflammation and ultimately leads to neuropathy, it regarded as crucial contributor cognitive impairment in OSA. However, the mechanisms by which IH-related neuroinflammation remain unclear need further exploration. Methods C57BL/6J mice were exposed experimental or normoxia for four weeks. Subsequently, cerebral...
This cross sectional investigation included 12,966 subjects with hypertension, a cohort of the China Stroke Primary Prevention Trial (CSPPT), randomized, multicenter clinical trial. study aimed to explore correlation between serum uric acid (SUA) concentration and hypertensive retinopathy in adults. Diagnosis was determined by non-mydriatic fundus photography classified Keith-Wagener-Barker (KWB) system. The SUA levels prevalence severity assessed statistical analysis. 9848 (75.95%) were...
Triptolide (TP), a principal bioactive component of traditional Chinese medicine Tripterygium wilfordii Hook. F., has been shown to have immunosuppressive/anti-inflammatory actions in vitro. Moreover, it is well established that inflammatory mechanisms contribute the progression hypertension-induced renal injury. Therefore, this study was performed determine protective effects TP on injury salt-sensitive hypertension and identify possible for TP-induced protection. Ten-week-old male C57BL/6...
Gestational diabetes mellitus (GDM) has affected a great number of pregnant women worldwide. Artemisia extracts have been found to exhibit potent antidiabetic effect in the treatment type 2 mellitus. We aimed examine effects extract on insulin resistance and lipid profiles GDM patients. Patients their second trimester were randomly assigned group (AE) or placebo (PO). They instructed consume either AE PO daily for period 10 weeks. Glucose adiponectin level assessed at baseline (week 0) after...
Preoperative distinction between transitional meningioma and atypical would aid the selection of appropriate surgical techniques, as well prognosis prediction. Here, we aimed to differentiate these two tumors using radiomic signatures based on preoperative, contrast-enhanced T1-weighted T2-weighted magnetic resonance imaging. A total 141 101 cases January 2014 December 2018 with a histopathologically confirmed diagnosis were retrospectively reviewed. All patients underwent imaging before...
Abstract Aims A post hoc analysis of RICAMIS trial to evaluate functional outcomes in relation patient age. Methods Patients were divided into six age groups. The primary outcome was excellent at 90 days, defined as modified Rankin Scale (mRS) score 0–1. Compared with patients receiving usual care alone, we investigated the association remote ischemic conditioning (RIC) effect each group and interaction between RIC Results Of 1776 patients, 498 assigned <60 years, 326 60 <65 325 65...
Background: Conventional prognostic models do not fully reflect the severity of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF). This study aimed to establish an effective and convenient nomogram for patients with HBV-related ACLF. Methods: A was developed based on a retrospective cohort 1,353 treated at Third Affiliated Hospital Sun Yat-sen University from January 2010 June 2016. The predictive accuracy discriminatory ability were determined by concordance index...
Abstract This study associated the liver proton density fat fraction (PDFF), measured by multi-echo Dixon (ME-Dixon) and breath-hold single-voxel high-speed T2-corrected 1 H magnetic resonance spectroscopy (HISTO) at 1.5 T, with serum biomarkers fibrosis stages. prospective enrolled 75 patients suspected of scheduled for biopsy 23 healthy participants normal function. The participant underwent ME-Dixon HISTO scanning. agreement PDFF (PDFF-D) (PDFF-H) were compared. Correlations between...
In recent years, significant advancements in radiofrequency ablation technology have notably enhanced arrhythmia treatment cardiology. Technological and increasing clinical adoption made a key therapy improving life quality for patients with conditions like atrial fibrillation (AF). Consequently, there has been marked increase research output, underscoring the technology's significance its potential Aims to comprehensively analyze cardiology's trends, identifying leading countries...
Cell death markers, M65 and M30, have been suggested to be sensitive markers of liver inflammation fibrosis in nonalcoholic fatty disease chronic hepatitis C. Our aim was investigate whether these were useful diagnosing B (CHB). We examined 186 patients with CHB; 18 sex- age-matched healthy subjects controls. The blood samples collected from CHB within 1 week before or after biopsy. According METAVIR score system, graded A0 A3, F0 F4. Serum M30 levels parallel the grades inflammation. M65,...