Agata Grzybkowska

ORCID: 0000-0003-0624-1836
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About
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Research Areas
  • Exercise and Physiological Responses
  • Iron Metabolism and Disorders
  • Vitamin C and Antioxidants Research
  • Adipose Tissue and Metabolism
  • Muscle metabolism and nutrition
  • Herbal Medicine Research Studies
  • Hemoglobinopathies and Related Disorders
  • RNA Research and Splicing
  • Cardiac Ischemia and Reperfusion
  • Trace Elements in Health
  • Molecular Biology Techniques and Applications
  • Vitamin D Research Studies
  • Heat shock proteins research
  • Erythropoietin and Anemia Treatment
  • Thermoregulation and physiological responses

Gdansk University of Physical Education and Sport
2018-2023

In this study, we investigated the effects of supplementation and exercise on expression genes associated with inflammation like CCL2, CRP, IL1, IL6, IL10 mRNA in elderly women.Twenty four participants divided randomly into two groups were subjected to 6 weeks same health training program (three times per week). SUP group (supplemented, n = 12, mean age 72.8 ± 5.26 years body mass 68.1 8.3 kg) received 1000 mg Vitamin C/day during period, while CON (control, 72.4 5.5 67.7 7.5 placebo.No...

10.1186/s12970-021-00416-6 article EN cc-by Journal of the International Society of Sports Nutrition 2021-01-02

Iron is essential for physical activity due to its role in energy production pathways and oxygen transportation via hemoglobin myoglobin. Changes iron-related biochemical parameters after exercise athletes are of substantial research interest, but molecular mechanisms such as gene expression still rarely tested sports. In this paper, we evaluated the mRNA levels genes related iron metabolism (PCBP1, PCBP2, FTL, FTH, TFRC) leukocytes 24 amateur runners at four time points: before, immediately...

10.3390/genes10060460 article EN Genes 2019-06-15

Alterations in iron metabolism after physical activity are manifested through the rise of blood hepcidin (Hpc) levels. However, many athletes, no changes Hpc levels observed exercise despite presence inflammation. The missing links could be erythropoietin (EPO) and erythroferrone (ERFE), which down-regulate biosynthesis. EPO, ERFE biosynthesis is modified by serum transferrin receptor 2. Consequently, we investigated whether marathon-induced iron-dependent. Twenty-nine healthy male marathon...

10.3390/ijerph17082781 article EN International Journal of Environmental Research and Public Health 2020-04-17

The proposal of this study was to evaluate the effect acute and ten-day ischaemic preconditioning (IPC) training procedure on Wingate Anaerobic Test (WAnT), ferritin H (FTH), L (FTL), transferrin receptor 1 (TFRC) mRNA expression in peripheral blood mononuclear cells (PBMC), anaerobic performance.34 healthy men volunteers (aged 20.7 ± 1.22 years) participated study. effects bilateral upper limb IPC sham controlled condition were assessed two experimental protocols: (a) influence (one time)...

10.1155/2019/9576876 article EN cc-by BioMed Research International 2019-04-11

Physical training and antioxidant supplementation may influence iron metabolism through reduced oxidative stress subsequent lowering of mRNA levels genes that are easily induced by this stress, including those responsible for homeostasis. Fifteen elderly women participated in our 12-week experiment, involving six weeks without supported oral 1000 mg vitamin C daily. The participants were divided into two groups (n = 7 group 1 n 8 2). In 1, we applied the first training, while 2 during...

10.3390/ijms21186469 article EN International Journal of Molecular Sciences 2020-09-05

The quantitative polymerase chain reaction (qRT-PCR) technique gives promising opportunities to detect and quantify RNA targets is commonly used in many research fields. This study aimed identify suitable reference genes for physical exercise omega-3 fatty acids supplementation intervention. Forty healthy, physically active men were exposed a 12-week eicosapentaenoic acid (EPA) docosahexaenoic (DHA) standardized endurance training protocol. Blood samples collected before after the...

10.3390/ijms24076734 article EN International Journal of Molecular Sciences 2023-04-04

It is a well known, that the physical activity promotes mental health. Physically active people relatively rarely suffer from psychosomatic and depressive disorders. possible differences in gene peripheral blood leukocytes may be associated with depression, especially genes participating inflammatory response. Thus, aim of our study was to investigate levels IL6 IL10 mRNA IL10/IL6 ratio healthy, physically individuals. One hundred healthy young men (20-23 years old) participated this study....

10.5604/01.3001.0012.4886 article EN Acta Neuropsychologica 2018-09-10

Abstract Background: In this study, we investigated the effects of supplementation and exercise on expression genes associated with inflammation like CCL2 , CRP, IL1 IL6 IL10 mRNA in elderly women. Methods: Twenty four participants divided randomly into two groups were subjected to 6 weeks same health training program (three times per week). SUP group (supplemented, n = 12, mean age 72.8 ± 5.26 years body mass 68.1 8.3 kg) received 1000mg Vitamin C/day during period, while CON (control, 72.4...

10.21203/rs.3.rs-113420/v2 preprint EN cc-by Research Square (Research Square) 2021-02-09

Abstract BackgroundIn this study we investigated the effects of supplementation and exercise on expression genes associated with inflammation like CCL2 , CRP, IL1 IL6 IL10 mRNA in elderly women.MethodsTwenty four participants divided randomly into two groups were subjected to 6 weeks same health training program (three times per week). SUP group (supplemented, n = 12, mean age 72.8 ± 5.26 years body mass 68.1 8.3 kg) received 1000 mg Vitamin C/day during period, while CON (control, 72.4 5.5...

10.21203/rs.3.rs-113420/v1 preprint EN cc-by Research Square (Research Square) 2020-12-01
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