A5101825350- Gut microbiota and health
- Intensive Care Unit Cognitive Disorders
- Clinical Nutrition and Gastroenterology
- Bacterial biofilms and quorum sensing
- Advanced Chemical Sensor Technologies
- Barrier Structure and Function Studies
- Water Treatment and Disinfection
- Erythrocyte Function and Pathophysiology
- Clostridium difficile and Clostridium perfringens research
- Pancreatitis Pathology and Treatment
- Antifungal resistance and susceptibility
- Enhanced Recovery After Surgery
- Sphingolipid Metabolism and Signaling
Jiangsu Academy of Agricultural Sciences
2020
Nanjing University
2011-2014
Nanjing General Hospital of Nanjing Military Command
2011-2014
Gastrointestinal bacteria and epithelia contribute to systemic inflammation infections in critically ill patients, but the gut microbiota these diseases has not been analyzed dynamically by molecular fingerprinting methods. This study aimed identify ileal flora dysbiosis pattern bacterial species that changed significantly a rat model of intestinal ischemia reperfusion illustrate time courses both epithelial alterations variations same injury. Forty-eight rats were randomized into eight...
Background The intestinal chronic rejection (CR) is the major limitation to long-term survival of transplanted organs. This study aimed investigate interaction between microbiota and epithelial integrity in transplantation, find out whether fish oil enhances recovery integrity. Methods/Principal Findings luminal mucosal composition CR rats were characterized by DGGE analysis at 190 days after transplant. specific bacterial species determined sequence analysis. Furthermore, changes...
To investigate the role of sphingosine kinase 1 (SphK1)/sphingosine 1-phosphate (S1P) signaling in inflammatory response severe acute pancreatitis (SAP).SAP is an process pancreas, which may lead to systemic syndrome and multiorgan dysfunction syndrome. SphK1 its product S1P have been implicated various immune cell functions. However, potential for SphK1/S1P SAP still unclear.Twenty-two patients with were enrolled this study. expression on peripheral neutrophils, monocytes, lymphocytes was...
The interactions of specific fungal phylotypes with immune cells have been recently documented; however, little is known whether gut microbiota influenced by aberrant response in immunosuppressive state. This study aimed to define the biologic impact lymphocyte depletion on and their relationship.Fifteen male cynomolgus monkeys CD52 antigen negative erythrocytes were administered intravenously a single dose (3.0 mg kg body weight) alemtuzumab. Depletion repopulation circulating mucosal...