- Lung Cancer Diagnosis and Treatment
- Cancer survivorship and care
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hippo pathway signaling and YAP/TAZ
- Polyamine Metabolism and Applications
- Autophagy in Disease and Therapy
- PI3K/AKT/mTOR signaling in cancer
- Head and Neck Cancer Studies
- Sirtuins and Resveratrol in Medicine
Chongqing Medical University
2022-2024
Chongqing Public Health Medical Center
2023
Breast cancer ranks the first in incidence of female and is most common threatening life health women worldwide.Tumor protein p53-regulated apoptosis-inducing 1 (TP53AIP1) a pro-apoptotic gene downstream p53. However, role TP53AIP1 BC needs to be investigated. In vitro vivo experiments were conducted assess biological functions associated mechanisms. Several bioinformatics analyses made, CCK8 assay, wound healing, transwell assays, colony formation EDU, flow cytometry, Immunofluorescence,...
Breast cancer is malignant tumours in women. A large amount of data analysis shows that Metformin has been shown to play a significance role reducing the risk breast cancer, but mechanism remains unclear. The hippo signalling pathway can be involved formation, metastasis and recurrence cancer. When YAP/TAZ activated, cells overcome contact inhibition enter state uncontrolled proliferation. Therefore, considered potential therapeutic target for Eighty patients, forty cases triple-negative...