A5040232238- Helicobacter pylori-related gastroenterology studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Animal Diversity and Health Studies
- Proteins in Food Systems
- Protein Hydrolysis and Bioactive Peptides
- PI3K/AKT/mTOR signaling in cancer
- Cancer Mechanisms and Therapy
Shiraz University of Medical Sciences
2021-2025
Islamic Azad University, Science and Research Branch
2023
Background: As the outbreak of COVID-19 has accelerated, an urgent need for finding strategies to combat virus is growing. Thus, gaining more knowledge on pathogenicity mechanism SARS-CoV-2, i.e. causing agent COVID-19, and its interaction with immune system utmost importance. Although this novel not well known yet, structural genetic similarity SARS-CoV as comparable pattern age-mortality relations suggest that some previous findings SARS could be applicable COVID-19. Objective: The aim...
Today, breast cancer and infectious diseases are very worrying that led to a widespread effort by researchers discover natural remedies with no side effects fight them. In the present study, we isolated camel milk protein fractions, casein whey proteins, hydrolyzed them using pepsin, trypsin, both enzymes. Screening of peptides anti-breast antibacterial activity against pathogens was performed. Peptides derived from fraction use enzymes showed good MCF-7 cell viability 7.13%. The separate...
2080 Background: Glioblastoma multiforme (GBM) remains one of the most aggressive brain tumors, characterized by poor survival rates and limited therapeutic success. Advancing treatment requires identifying molecular drivers tumor progression therapy resistance. Integrated transcriptomic analyses offer a powerful means to uncover pathogenic pathways, targets, refine prognostic tools. This study aimed explore GBM’s landscape identify survival-relevant genes actionable ultimately paving way...
e20038 Background: Lung adenocarcinoma (LUAD) is among the most frequently diagnosed cancers worldwide and remains a leading cause of cancer-related mortality. Despite advances in targeted therapies, LUAD challenging to treat, partly due its genetic heterogeneity multifactorial progression. We performed an integrative transcriptomic analysis better characterize molecular underpinnings LUAD, identify clinically relevant prognostic markers, highlight potential therapeutic avenues. Methods:...
Gastric cancer is the fourth cause of death globally, and gastric adenocarcinoma its most common type. Efforts for treatment have increased median survival rate by only seven months. Due to relatively low response surgery adjuvant therapy, as well complex role risk factors in incidences, such protein-pomp inhibitors (PPIs) viral bacterial infections, we aimed study pathological pathways involved development investigate possible medications systems biology bioinformatics tools. In this study,...