A5061989741- Polymer Surface Interaction Studies
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Hydrogels: synthesis, properties, applications
- Antimicrobial agents and applications
- X-ray Spectroscopy and Fluorescence Analysis
- Marine Biology and Environmental Chemistry
- Polymer Nanocomposites and Properties
- biodegradable polymer synthesis and properties
- Orthopaedic implants and arthroplasty
- Surface Modification and Superhydrophobicity
- Hemostasis and retained surgical items
- Surgical Sutures and Adhesives
- Nanoplatforms for cancer theranostics
- Wound Healing and Treatments
- Efficiency Analysis Using DEA
- Environmental Impact and Sustainability
- Advanced Polymer Synthesis and Characterization
- Cholesterol and Lipid Metabolism
- Orthopedic Infections and Treatments
- Graphene and Nanomaterials Applications
- Energy, Environment, Economic Growth
- Nuclear Physics and Applications
- Photodynamic Therapy Research Studies
- Political Economy and Marxism
Nanjing Normal University
2016-2025
University of Shanghai for Science and Technology
2025
Chinese Academy of Sciences
2014-2024
University of Chinese Academy of Sciences
2024
Institute of Biophysics
2014-2024
Tongji University
2021
Jishou University
2021
Changzhou University
2021
Jiangsu University of Technology
2021
Lanzhou University
2008-2020
Abstract Most of the current bioadhesives cannot perform well on bleeding tissues while postoperative adhesion is a general but serious clinical issue. Here, three‐layer biodegradable Janus tissue patch (J‐TP) that able to simultaneously enable efficient closure wounds with significantly promoted clotting ability and suppressed reported. A dry adhesive hydrogel bottom layer J‐TP can form rapid (within 15 s) strong (tensile strength up 98 kPa) bleeding/wet high bursting pressure (about 312.5...
Although NPC1L1 is required for intestinal cholesterol absorption, data demonstrating mechanisms by which this protein facilitates the process are few. In study, a hepatoma cell line stably expressing human was established, and uptake studied. A relationship between intracellular trafficking apparent. At steady state, proteins localized predominantly to transferrin-positive endocytic recycling compartment, where free also accumulated as revealed filipin staining. Interestingly, acute...
A p-vinylbenzyl sulfobetaine was grafted from cellulose membrane (CM) using surface-initiated atom transfer radical polymerization for blood compatibility improvement. Surface structure, wettability, morphology, and thermal stability of the CM substrates before after modification were characterized by attenuated total reflectance Fourier transform infrared spectra, X-ray photoelectron spectroscopy measurement, water contact angle atomic force microscopy, thermogravimetric analysis,...
Protein lysine malonylation, a newly identified protein post-translational modification (PTM), has been proved to be evolutionarily conserved and is present in both eukaryotic prokaryotic cells. However, its potential roles associated with human diseases remain largely unknown. In the study, we observed an elevated malonylation screening of seven acylations liver tissues db/db mice, which typical model type 2 diabetes. We also detected ob/ob another then performed affinity enrichment coupled...
Blood compatibility and cytocompatibility are key requirements of blood-contacting biomaterials for biomedical applications. Here, we showed the general zwitterionic surface modification cellulose membrane (CM) substrates, via surface-initiated atom transfer radical polymerization (SI-ATRP), to enhance anti-biofouling ability without compromising substrates. Robust X-ray photoelectron spectroscopy (XPS) characterization revealed successful construction three brushes, which significantly...
Bacterial infection and oxidative stress hinder clinical wound healing. Therefore, dressings with antibacterial antioxidative properties are urgently needed. In this study, a type of quaternized lignin (QL) functionalized poly(hexamethylene biguanide) hydrochloride (PHMB) complex incorporated polyacrylamide (QL-PHMB-PAM) hydrogel was developed as multifunctional dressing material for the promotion infected repair. Owing to abundant catechol groups lignin, QL-PHMB-PAM exhibited robust...
Osteoconductive mineral coatings are beneficial for improving the osteointegration of metallic orthopedic/dental implants, but achieving adequate structural integration between surface minerals and underlying substrates has been a significant challenge. Here, we report covalent grafting zwitterionic poly(sulfobetaine methacrylate) (pSBMA) brushes on Ti6Al4V to promote surface-mineralization hydroxyapatite with enhanced coverage mineral-substrate interfacial adhesion. We first optimized atom...
ROS conversion can increase the bactericidal efficiency (against S. aureus ) of an Eosin Y based PDT system from 37.9% to 99.9%, elevate inactivation MRSA 26.9% 99.4%, and enhance eradication rate biofilm 69% 90%.
Good's buffers have been widely applied in cell/organ culture over the past half a century as biocompatible pH stabilizers. However, emergence of severe adverse effects, such cellular uptake, lysosomal autophagic activation, and visible light-induced cytotoxicity, raises serious questions its biocompatibility while underlying mechanism was unclear. Here we report that riboflavin (RF, component cell medium) generates 1O2, ·OH, O2•- under light exposure during regular manipulation. These short...
AB diblock copolymers comprised of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) and poly(3-methacryloxypropyl trimethoxysilane) (PMTSi) segments, which are used for biocompatible coatings, were investigated. Block with various compositions synthesized by atomic transfer radical polymerization (ATRP). The obtained dissolved in an ethanol solution, dynamic light scattering showed that all block capable existing as micelles. After a convenient "one-step" reaction, the cellulose...
Chronic wounds are associated with a metabolically imbalanced physiological microenvironment. However, conventional wound dressings inadequate for treating chronic due to their weak bioactivity. Electroactive essential modulating myriad of biological processes, particularly antioxidant activity and cell migration. Herein, we designed conductive hydrogel flexible, biodegradable, electroactive properties using mussel-inspired method. This was prepared by inducing...
Developing a facile but efficient anti-fouling surface coating is highly required for metallic implants. Here, we report two kinds of zwitterionic copolymers (both random and block) bearing phosphonic/phosphonate motifs/segments as novel metal anchorable antifouling coatings. Through conventional free radical polymerization reversible addition-fragmentation chain transfer (RAFT) polymerization, three types zwitterionic-phosphonic with varying mol. ratios (9 : 1, 8 2, 6 4)...
Abstract The three-stage super-efficiency slack-based measure and data envelopment analysis (SBM-DEA) model with undesirable outputs is used to calculate carbon emissions efficiency of industrial energy (CEEIE) 30 provinces in China from 2000 2017. Then ArcGIS software illustrate the spatial distribution CEEIE, Dagum Gini ratio calculated decompose regional difference. results show that CEEIE changes disorder order characterized high or low cluster space over time. total coefficient...