A5002529038- Transcranial Magnetic Stimulation Studies
- Stroke Rehabilitation and Recovery
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Pain Management and Treatment
- Muscle activation and electromyography studies
- Botulinum Toxin and Related Neurological Disorders
- Advanced MRI Techniques and Applications
- Neural and Behavioral Psychology Studies
- Heart Rate Variability and Autonomic Control
- Myofascial pain diagnosis and treatment
- Spinal Cord Injury Research
- Vestibular and auditory disorders
- Acute Ischemic Stroke Management
- Musculoskeletal pain and rehabilitation
- Advanced Neuroimaging Techniques and Applications
Clinique Romande de Réadaptation
2018-2024
Suva
2022
Cortical excitation/inhibition dynamics have been suggested as a key mechanism occurring after stroke. Their supportive or maladaptive role in the course of recovery is still not completely understood. Here, we used transcranial magnetic stimulation (TMS)-electroencephalography coupling to study cortical reactivity and intracortical GABAergic inhibition, well their relationship residual motor function longitudinally patients with
Effective, patient-tailored rehabilitation to restore upper-limb motor function in severely impaired stroke patients is still missing. If suitably combined and administered a personalized fashion, neurotechnologies offer large potential assist rehabilitative therapies enhance individual treatment effects. AVANCER (clinicaltrials.gov NCT04448483) two-center proof-of-concept trial with an based cumulative longitudinal intervention design aiming at reducing impairment affected the help of...
Abstract Impairment of hand motor function is a frequent consequence after stroke and strongly determines the ability to regain self-determined life. An influential research strategy for improving deficits combined application behavioral training non-invasive brain stimulation cortex (M1). However, convincing clinical translation present strategies has not been achieved yet. One alternative innovative approach target functionally relevant network-based architecture, e.g., dynamic...
Despite recent improvements, complete motor recovery occurs in <15% of stroke patients. To improve the therapeutic outcomes, there is a strong need to tailor treatments each individual patient. However, lack knowledge concerning precise neuronal mechanisms underlying degree and course its differences, especially view brain network properties despite fact that it became more clear disorder. The TiMeS project longitudinal exploratory study aiming at characterizing phenotypes large,...
Task-specific training constitutes a core element for evidence-based rehabilitation strategies targeted at improving upper extremity activity after stroke. Its combination with additional treatment and neurotechnology-based solutions could further improve patients' outcomes. Here, we studied the effect of gamified robot-assisted limb motor on performance, skill learning, transfer respect to non-gamified control condition group chronic stroke survivors. The results suggest that strategy in...
Most studies on stroke have been designed to examine one deficit in isolation; yet, survivors often multiple deficits different domains. While the mechanisms underlying multiple-domain remain poorly understood, network-theoretical methods may open new avenues of understanding.Fifty subacute patients (7±3days poststroke) underwent diffusion-weighted magnetic resonance imaging and a battery clinical tests motor cognitive functions. We defined indices impairment strength, dexterity, attention....
The article considers clinical manifestations, pathogenesis and therapy of complex regional pain syndrome. historical reference on this issue is provided. description case syndrome with positive effect against the background applied presented. It emphasized that besides complications related to monitoring category patients, presented an evidence inadequate studying pathophysiologic concepts explaining development are presented: activation neurogenous inflammatory alterations, pathologic...
Abstract Objective Cortical excitation/inhibition dynamics have been suggested as a key mechanism occurring after stroke. Their supportive or maladaptive role in the course of recovery is still not completely understood. Here, we used TMS-EEG coupling to study cortical reactivity and intracortical GABAergic inhibition, well their relationship residual motor function longitudinally large cohort stroke patients. Methods EEG responses evoked by TMS applied ipsilesional cortex were acquired 66...
Abstract Background Most studies on stroke have been designed to examine one deficit in isolation, yet survivors often multiple deficits different domains. While the mechanisms underlying multiple-domain remain poorly understood, network-theoretical methods may open new avenues of understanding. Methods 50 subacute patients (7±3days post-stroke) underwent diffusion-weighted magnetic resonance imaging and a battery clinical tests motor cognitive functions. We defined indices impairment...