Andrea Crema

ORCID: 0000-0003-4451-1817
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About
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Research Areas
  • Stroke Rehabilitation and Recovery
  • Muscle activation and electromyography studies
  • EEG and Brain-Computer Interfaces
  • Prosthetics and Rehabilitation Robotics
  • Transcranial Magnetic Stimulation Studies
  • Motor Control and Adaptation
  • Botulinum Toxin and Related Neurological Disorders
  • Neuroscience and Neural Engineering
  • Sports Performance and Training
  • Medical Malpractice and Liability Issues
  • Acute Ischemic Stroke Management
  • Advanced Sensor and Energy Harvesting Materials
  • Spinal Cord Injury Research
  • Spatial Neglect and Hemispheric Dysfunction
  • Ethics and bioethics in healthcare
  • Cerebral Palsy and Movement Disorders
  • Ethics in medical practice
  • Action Observation and Synchronization
  • Robot Manipulation and Learning
  • Sports injuries and prevention

École Polytechnique Fédérale de Lausanne
2013-2023

University of Geneva
2022-2023

Wyss Center for Bio and Neuroengineering
2021-2022

MUNDUS is an assistive framework for recovering direct interaction capability of severely motor impaired people based on arm reaching and hand functions. It aims at achieving personalization, modularity maximization the user’s involvement in systems. To this, exploits any residual control end-user can be adapted to level severity or progression disease allowing user voluntarily interact with environment. target pathologies are high-level spinal cord injury (SCI) neurodegenerative genetic...

10.1186/1743-0003-10-66 article EN cc-by Journal of NeuroEngineering and Rehabilitation 2013-01-01

Reaching and grasping impairments significantly affect the quality of life for people who have experienced a stroke or spinal cord injury. The long-term well-being patients varies greatly according to restorable residual capabilities. Electrical stimulation could be promising solution restore motor functions in these conditions, but its use is not clinically widespread. Here, we introduce HandNMES, an electrode array (EA) neuromuscular electrical (NMES) aimed at grasp training assistance....

10.1109/tnsre.2017.2703151 article EN IEEE Transactions on Neural Systems and Rehabilitation Engineering 2017-05-12

The continuous stream of multisensory information between the brain and body during body-environment interactions is crucial to maintain updated representation perceived dimensions parts (metric representation) space around (the peripersonal space). Such flow signals often limited by upper limb sensorimotor deficits after stroke. This would suggest presence systematic distortions metric in chronic patients with persistent deficits. We assessed 60 stroke unilateral motor deficits, comparison...

10.1093/braincomms/fcac179 article EN cc-by Brain Communications 2022-07-04

Effective, patient-tailored rehabilitation to restore upper-limb motor function in severely impaired stroke patients is still missing. If suitably combined and administered a personalized fashion, neurotechnologies offer large potential assist rehabilitative therapies enhance individual treatment effects. AVANCER (clinicaltrials.gov NCT04448483) two-center proof-of-concept trial with an based cumulative longitudinal intervention design aiming at reducing impairment affected the help of...

10.3389/fneur.2022.919511 article EN cc-by Frontiers in Neurology 2022-07-07

Clinicians constantly face the need to rehabilitate stroke patients re-establish coordinate reach and grasp. Rehabilitation, be effective, requires intensive repetitive tasks. Assist-as-needed motion control for grasp assistance are usually treated separately, mostly based on virtual reality games. To increase clinical outcome, we designed flexible modules a platform, able provide synchronous support interact with common objects. An upper limb exoskeleton provides reaching support,...

10.1109/ner.2015.7146710 article EN 2015-04-01

Active functional rehabilitation procedures, exoskeleton application and prosthesis employment are essential tools for the society life reinstatement of subjects affected by neuromuscular disorders or victims serious physical accident. In this paper we propose a closed-loop system control Functional Electrical Stimulation (FES) based on Average Threshold Crossing (ATC) event-driven processing technique applied to sEMG signal. It allows an energy saving, low complex, real-time muscle activity...

10.1109/icecs46596.2019.8965153 article EN 2021 28th IEEE International Conference on Electronics, Circuits, and Systems (ICECS) 2019-11-01

The paper presents a multisensory and multimodal device for neuromuscular rehabilitation of the upper limb, designed to enable enriched treatment in both clinical home environments. Originating from an existing low-cost, variable-stiffness device, it expands its functionalities by integrating additional modules order augment application scenarios applicable techniques. newly developed system focuses on integration wearable electrical stimulation system, virtual scenario, low-cost unobtrusive...

10.1177/2055668316680980 article EN cc-by-nc Journal of Rehabilitation and Assistive Technologies Engineering 2016-01-01

Many research groups are currently working with robotic devices for hand grasp rehabilitation and restoration. A common problem in this area is the fact that existing commercially available exoskeletons able to provide gravity compensation of shoulder elbow but do not any support grasping releasing movements hand. The lack a flexible technology reduces possible ways which clinicians can deal issue personalized, effective rehabilitation. This paper presents new software allows FES assisted...

10.1109/iembs.2011.6090833 article EN Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2011-08-01

Muscle synergies have been proposed as building blocks that simplify the construction of movements, and a method to study motor behavior. However, pre-processing EMG signals factorization algorithm may impact on their extraction meaning. This preliminary work aimed at investigating influence selection muscles muscle analysis. In particular, extracted from datasets including different upper limb muscles, recorded during execution planar reaching grasping movements. Results suggested amount...

10.1109/ner.2013.6696001 article EN 2013-11-01

Exosuits typically provide limited mechanical support and rely on a user's residual functional ability. However, people with neurological impairments often suffer from both motor sensory deficits that limit the assistance an exosuit can provide. To overcome these limitations, we developed REINFORCE system, complements provided by exosuit, Myosuit, (1) electrical stimulation to enhance activities of leg muscles, (2) transcutaneous nerve restore somatosensory information. It consists fully...

10.1109/icorr58425.2023.10304701 article EN 2023-09-24

Enriched environments and tools are believed to promote grasp rehabilitation after stroke. We designed S2, an interactive system consisting of smart objects, custom orthoses for selective constraining, electrode array forearm NMES. Motor improvements perceived usability a new enriched upper limb training sub-acute stroke patients was assessed in this interim analysis. Inclusion criteria: with MMSE>20, ipsilesional MI>80%, contralesional MI<80%. Effects 30-min therapy supplements,...

10.3390/s21206739 article EN cc-by Sensors 2021-10-11

The Helping Hand (HH) system is a novel grasp rehabilitation platform aimed at simplifying the clinical usage of wearable electrode arrays for neuromuscular electrical stimulation (NMES). In randomized dose-matched, study we evaluate usability and effectiveness HH treatment, other enriched upper limb treatments, compare outcomes. This paper shows preliminary results trial on 5 chronic stroke patients throughout 9 weeks, 3 hours per week, hand preshaping training.

10.1109/ner.2017.8008313 article EN 2017-05-01

The paper presents a multisensory and multimodal device for neuromuscular rehabilitation of the upper limb. system integrates variable-stiffness device, wearable electrical stimulation system, virtual environment, low-cost unobtrusive sensory patient model adapting training task parameters. It monitors user behaviour its evolution throughout entire period. enables patients, integrating features currently unavailable in single off-the-shelf devices upper-limb rehabilitation.

10.1145/3051488.3051502 article EN 2016-10-13

Stroke is the leading cause of long term disability, causing both motor and cognitive impairments. impacts somatosensory capabilities individual, distorted perception environment body. Consequently persons with grasp impairments are subject to activity limitations participation restriction because perceptive reduced control affected limb. Recent medical research has demonstrated that contextual matching intent rehabilitation assistance a decisive factor for success therapies involve...

10.5075/epfl-thesis-7593 article EN 2017-01-01
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