A5058332212- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Genetic and Kidney Cyst Diseases
- Liver Disease and Transplantation
- Lymphoma Diagnosis and Treatment
- Renal and related cancers
- FOXO transcription factor regulation
- Polyomavirus and related diseases
- Bone Tissue Engineering Materials
- Neuroblastoma Research and Treatments
- Vascular Malformations and Hemangiomas
- Intraperitoneal and Appendiceal Malignancies
- Vascular Tumors and Angiosarcomas
- Ovarian cancer diagnosis and treatment
- Glycogen Storage Diseases and Myoclonus
- Liver Diseases and Immunity
- Viral-associated cancers and disorders
- Genetic factors in colorectal cancer
- Orthopaedic implants and arthroplasty
- Dental materials and restorations
- Omental and Epiploic Conditions
- Drug-Induced Hepatotoxicity and Protection
- Hepatitis B Virus Studies
- Renal cell carcinoma treatment
University of Cologne
2022-2025
University Hospital Cologne
2022-2024
Centrum für Integrierte Onkologie
2023
University Hospital Bonn
2022
Klinik und Poliklinik für Psychosomatik und Psychotherapie
2022
Fischer (Germany)
1986
Carlsberg Foundation
1938
Abstract Wilms tumors (WTs) are histologically diverse childhood cancers with variable contributions of blastema, stroma, and epithelia. A variety cancer genes operate in WTs, including the tripartite‐motif‐containing‐28 gene ( TRIM28 ). Case reports small case series suggest that mutations associated epithelial morphology WT predisposition. Here, we systematically investigated prevalence inactivation predisposing a cohort 126 WTs >2/3 cells, spanning 20 years biobanking German...
A woman in her 50s presented to the hospital with new-onset jaundice and ascites. Her medical history included a melanoma of right shoulder, diagnosed 8 months before, for which she had received four cycles ipilimumab nivolumab. Due oncological previous immunotherapy, an immune-checkpoint-inhibitor (ICI)-induced hepatitis was suspected, high-dose corticosteroid treatment initiated. However, as there no improvement liver function tests, percutaneous biopsy performed further diagnostic...
The occurrence of mammary carcinoma in mice and an epidermoid cyst, following repeated autologous transplantation tissue has been reported earlier papers (1). present report concerns a round-cell sarcoma which appeared the same procedure. It is uncertain whether this tumor arose from stroma or interstitial cells transplanted whether, indeed, it may not be coincidence having nothing to do with graft. Exp. No. 1666–3: On Oct. 26, 1936, right inguinal gland mouse was removed, sutured piece tail...
We report on the incidental finding of Kaposi sarcoma colon in setting refractory ulcerative colitis treatment. The patient was under long-term immunosuppression with infliximab, vedolizumab, and prednisolone. Serologic analysis excluded human immunodeficiency virus (HIV) infection.Wir berichten über den Zufallsbefund eines Kaposi-Sarkoms des Kolons bei schwerer therapierefraktärer Colitis ulcerosa. Die Patientin war zuvor lange immunsuppressiv mit Infliximab, Vedolizumab und Prednisolon...
We report on the incidental finding of a FOXL2 mutated adult granulosa cell tumour ovary with thecoma-like foci, rare entity recently described by Jennifer N. Stall and Robert H. Young in series sixteen cases 2019, displaying features differing from conventional tumour. Our aim is to specify morphologic molecular particularities this presumably underrecognized finding, short presentation typical clinical context. Awareness challenging neoplasm indeterminate course crucial routine diagnostics.
Giant hepatic cavernous hemangioma with multiple satellite nodules is a rare subtype of hemangioma, the most common vascular liver tumor. We report on tumor unusual histologic features: (1) Finger-like infiltration pattern; (2) lack encapsulation; (3) blurred tumor/liver interface; and (4) massive satellitosis-referring to article "Hepatic hemangioma: underrecognized associated features".A 60-year-old man presented increasing uncharacteristic abdominal discomfort mildly elevated blood...
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Abstract We report on two cases of orthotopic liver transplantation (OLTX) due to SARS-Cov2-associated secondary sclerosing cholangitis (SSC) following long-term artificial respiration and extra-corporal membrane oxygenation in intensive care. Under these conditions, SSC is a rapidly progredient biliary disease featuring degenerative cholangiopathy, loss bile ducts, ductular parenchymal cholestasis, fibrosis, finally cirrhosis. Reduced perfusion the peribiliary plexus, severe concurrent...
Abstract Background hTERT promotor mutation represents a common and early event in hepatocarcinogenesis. Its linkage with the morphologic status of underlying liver tissue is not really understood. We analysed connection between histopathological changes tumour bearing occurrence hepatocellular carcinoma, correlated clinical data. Methods The study cohort comprised 160 histologically confirmed carcinomas (HCC) cirrhosis non-cirrhosis which were investigated for mutation. Frequency HCC was...