A5100330740- Radiomics and Machine Learning in Medical Imaging
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Synthesis and biological activity
- Crystal structures of chemical compounds
- Corneal surgery and disorders
- Consumer Attitudes and Food Labeling
- Traumatic Ocular and Foreign Body Injuries
- Natural product bioactivities and synthesis
- Medical Imaging and Analysis
- Peptidase Inhibition and Analysis
- Nutritional Studies and Diet
- Synthesis of Organic Compounds
- Advanced Neural Network Applications
- Medical Research and Treatments
- Parasitic infections in humans and animals
- Fluorine in Organic Chemistry
- Neuroendocrine Tumor Research Advances
- Management of metastatic bone disease
- Retinopathy of Prematurity Studies
- Biological and pharmacological studies of plants
- Medical Image Segmentation Techniques
- Antioxidant Activity and Oxidative Stress
- Traditional Chinese Medicine Studies
- SARS-CoV-2 and COVID-19 Research
Chinese Academy of Sciences
2005-2025
Beijing National Laboratory for Molecular Sciences
2022-2025
Huazhong University of Science and Technology
2025
Chinese Center For Disease Control and Prevention
2021-2024
Yunnan University
2022-2024
Yantai University
2020-2023
Shanghai Artificial Intelligence Laboratory
2022-2023
National Health and Family Planning Commission
2023
Beijing Academy of Artificial Intelligence
2022-2023
Jinan Central Hospital
2023
Background: To evaluate the long-term efficacy and safety of topical 1% atropine for retarding moderate myopia. Methods: A randomized, controlled study evaluating placebo in 660 Chinese children. Patients received drops q1month 24 months, then q2month 12 followed by no months. Spherical equivalent, axial length, intraocular pressure atropine-related side effects were examined at 6, 12, 24, 36 48 months all Results: myopic progression, length augmentation, progression rate significantly...
Many fluorophores/probes suffer from the interference of albumin in biosystems. Herein, we propose an effective strategy to overcome this by virtue both albumin-insensitive fluorophore and its changeable π-conjugation, demonstrate designing oxazine-based fluorogenic probe for aminopeptidase N (APN). The modification on atom oxazine with alanine through a cleavable linker locks resulting non-conjugated, colorless non-fluorescent state, so non-specific interaction produces no spectroscopic...
Abstract Background Whether and to what extent outdoor activity screen time are relevant adiposity among rural adolescents remain largely unknown as most of evidence was generated from high-income countries urban areas. This study aimed investigate associations with early living in southwest China. Methods In this cross-sectional study, seventh graders ( n = 2264) were recruited 10 middle schools a county. Overweight obesity assessed using adolescents’ body mass index waist circumference....
It is essential to understand the impact of different dietary pattern trajectories on health over time. Therefore, we aimed explore long-term patterns among Chinese adults and examine prospective association between trajectory groups risk overweight/obesity. The sample was 9299 aged 18 years or older from China Health Nutrition Survey (CHNS) 1991 2018. We used factor analysis identify group-based modeling trajectories. Three a southern modern four meat were identified. Participants who...
The warning label is identified as a simple front-of-package labeling format that assists consumers in making healthier food choices at the point of purchase. color and/or shape design elements packaging labels can influence understanding and purchase intention outcomes. This study aimed to explore perceptions regarding differently designed (WLs) identify possibly suitable Chinese context. Using qualitative approach, we collected data through 12 focus group discussions consisting 116...
To evaluate the effect of 0.05% atropine on control myopia for 2y (phase I) and spherical equivalent refraction (SER) progression 1y II) after its withdrawal in Chinese myopic children.Totally 142 children with were randomly assigned to group or placebo group. In phase I, received 1 treatment each eye daily. II, patients no treatment. Axial length (AL), SER, intraocular pressure (IOP) atropine-related side effects assessed at 6 months' intervals.During mean change SER was -0.46±0.30 D group,...
<title>Abstract</title> Ischemic stroke impacts glymphatic function, but its role in prognosis remains unclear. This study evaluated function 146 participants, including non-stroke (healthy controls, n = 48; nonvascular cognitive impairment patients, 47) and ischemic cohorts (n 51). The bilateral diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index, choroid plexus (CP), (PVS) volume ratio, which represent system, were compared across two between pre-rehabilitation...
Ischemic stroke impacts glymphatic function, but its role in prognosis remains unclear. This study evaluated function 146 participants, including non-stroke (healthy controls, n = 48; nonvascular cognitive impairment patients, 47) and ischemic cohorts (n 51). The bilateral diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index, choroid plexus (CP), (PVS) volume ratio, which represent system, were compared across two between pre-rehabilitation (Time 1) 30 days...
Cystic echinococcosis is a chronic disease caused by infection with the larvae of Echinococcus granulosus. The parasite's ability to establish persistent partly due its evolving immune evasion strategies. One strategy may involve protective effect arginase, which impedes control pathogens or tumors, whereas it remains largely unknown during E. granulosus infection. Here, we analyzed whether arginase was produced in peritoneal cells and assessed role immunosuppression mice infected...
Ten new N ‐substituted‐3,5‐bis(arylidene)‐4‐piperidone derivatives (series 1 and 2 ) were synthesized subsequently evaluated against human carcinoma cell lines SW 1990, MIA PaCa‐2, PG ‐ BE 1, NCI ‐H460, SK BR ‐3 for cytotoxic activity by the CCK ‐8 method, their fluorescent properties investigated as well. The compounds confirmed to display greater neoplastic cells, approximately 50% of IC 50 values lower than 5 μ m . In particular, 1a , 1c 1d, 1e bearing 3‐bromophenyl groups revealed most...
To determine whether haemoperfusion (HP) with continuous venovenous haemofiltration (CVVH) improves the survival of patients acute paraquat poisoning, compared those treated using HP alone.Medical records poisoning were analysed. Patients randomised to undergo or + CVVH within 24 h ingestion. Mortality rate, duration and cause death recorded.There no significant differences in mortality rate between group (n = 458) 226) (57.4% 58.4%, respectively). The mean was significantly longer than (8.6...
Appropriate dietary patterns for preserving cognitive function in China remains unknown. This study explored the association between pattern and Chinese population. A total of 6308 adults aged 55 above who participated Health Nutrition Survey at least two waves from 1997 to 2018 were selected. The was determined using reduced rank regression method with responses regarding vitamin C, E, zinc, iron, copper, selenium intakes. We used a three-level random coefficient model evaluate association....
Objective: To evaluate the effects of long-term wear and discontinuation orthokeratology lenses (Orth-K) on biological parameters eyeballs in children with myopia. Methods: In this prospective study, a total 308 subjects myopia were randomized to receive Orth-K (n = 154) or single vision spectacles (SVS) for 12 months followed by 1-month withdrawal period. The axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD) lens (CLT) assessed at baseline, 6 months, 13...
Herein, an ionic-liquid-based effervescence-enhanced magnetic solid-phase extraction (ILE-MSPE) for the detection of organophosphorus pesticides in waters is reported with high stability and portability rapid sample pretreatment field.
The coronavirus disease-2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome 2 (SARS-CoV-2) has seriously affected public health around world. In-depth studies on pathogenic mechanisms of SARS-CoV-2 is urgently necessary for prevention. However, most laboratory have to be carried out in bio-safety level 3 (BSL-3) laboratories, greatly restricting progress relevant experiments. In this study, we used a bacterial artificial chromosome (BAC) method assemble replication and...
Abstract C 17 H 14 FNO 2 , monoclinic, P 1 / c (no. 14), a = 14.0279(13) Å, b 7.0527(5) 14.4150(16) β 113.165(12)°, V 1311.2(2) Å 3 Z 4, R gt ( F ) 0.0524, wR ref 0.1358, T 100 K.
To describe the prevalence of overweight, obesity, and central obesity among adult residents aged 18 years above in 10 provinces(autonomous regions) China 2023, to analyze trends 2000-2023.