A5013473795- Advanced Battery Materials and Technologies
- Advancements in Battery Materials
- Advanced Battery Technologies Research
- Molecular Sensors and Ion Detection
- Nanoplatforms for cancer theranostics
- Sulfur Compounds in Biology
- Nitric Oxide and Endothelin Effects
- Advanced battery technologies research
- Computational Drug Discovery Methods
- Photoacoustic and Ultrasonic Imaging
- Neuroendocrine Tumor Research Advances
- Analytical Chemistry and Sensors
- Pneumocystis jirovecii pneumonia detection and treatment
- Electrocatalysts for Energy Conversion
- Immune Response and Inflammation
- Peptidase Inhibition and Analysis
- Cholinesterase and Neurodegenerative Diseases
- Supercapacitor Materials and Fabrication
- Receptor Mechanisms and Signaling
- Muscle Physiology and Disorders
- Electrochemical sensors and biosensors
- Luminescence and Fluorescent Materials
- Synthesis and Properties of Aromatic Compounds
- Hydrogen Storage and Materials
- Photoreceptor and optogenetics research
University of Science and Technology of China
2022-2025
Hefei National Center for Physical Sciences at Nanoscale
2022-2025
Chinese Academy of Sciences
2021-2025
Beijing National Laboratory for Molecular Sciences
2021-2025
Huazhong University of Science and Technology
2025
University of Chinese Academy of Sciences
2022-2024
Yanshan University
2024
State Key Laboratory of Metastable Materials Science and Technology
2024
China Iron and Steel Research Institute Group
2022
Shandong Normal University
2018-2021
Fluorescence bioimaging through the second near-infrared window (NIR-II, 1000–1700 nm) has attracted much attention due to its deep penetration and high contrast. However, exploring new fluorescent materials, especially small molecular fluorophores with long wavelength brightness, is still quite challenging. By expanding π-conjugation enhancing intramolecular charge transfer effect, herein we report a series of xanthene-based NIR-II dyes, named VIXs. Among these VIX-4 exhibits best...
The electrolyte solvation structure and the solid-electrolyte interphase (SEI) formation are critical to dictate morphology of lithium deposition in organic electrolytes. However, link between SEI composition its implications on evolution poorly understood. Herein, we use a single-salt single-solvent model system systematically study correlation structure, process morphology. mechanism is thoroughly investigated using cryo-electron microscopy characterizations computational simulations. It...
Abstract Constraining the electrochemical reactivity of free solvent molecules is pivotal for developing high-voltage lithium metal batteries, especially ether solvents with high Li compatibility but low oxidation stability ( <4.0 V vs + /Li). The typical concentration electrolyte approach relies on nearly saturated coordination to molecules, which confronted severe side reactions under voltages >4.4 V) and extensive exothermic between reactive anions. Herein, we propose a molecular...
Based on a novel Golgi-targeting phenylsulfonamide group, two-photon (TP) fluorescent probe, Np-Golgi, was developed for <italic>in situ</italic> H<sub>2</sub>O<sub>2</sub> ratiometric imaging in living systems.
Nitric oxide (NO) is a crucial neurotransmitter participating in many biological processes via nitrosylation reaction. NO produced diverse subcellular regions also regulates the function of cells different manners. A Golgi apparatus rich nitric synthase and may serve as potential therapeutic target for Alzheimer's disease (AD). However, due to lack an effective tool, it difficult reveal relationship between Golgi-NO AD. Herein, we report first Golgi-targeted fluorescent probe sensing imaging...
Abstract The development of lithium–metal batteries (LMBs) has emerged as a mainstream approach for achieving high‐energy‐density energy storage devices. stability electrochemical interfaces plays an essential role in realizing stable and long‐life LMBs. Despite extensive comprehensive research on the lithium anode interface, there is limited focus cathode particularly regarding high‐voltage transition metal oxide materials. In this review, challenges associated with developing materials are...
Abstract Metallene is considered as an emerging family of electrocatalysts due to its atomically layered structure and unique surface stress. Here we propose a strategy modulate the Bader charge transfer (BCT) between Pd oxygenated intermediates via p ‐ d electronic interaction by introducing single‐atom ‐block metal (M=In, Sn, Pb, Bi) into metallene nanosheets towards efficient oxygen reduction reaction (ORR). X‐ray absorption photoelectron spectroscopy suggests that doping metals could...
Many fluorophores/probes suffer from the interference of albumin in biosystems. Herein, we propose an effective strategy to overcome this by virtue both albumin-insensitive fluorophore and its changeable π-conjugation, demonstrate designing oxazine-based fluorogenic probe for aminopeptidase N (APN). The modification on atom oxazine with alanine through a cleavable linker locks resulting non-conjugated, colorless non-fluorescent state, so non-specific interaction produces no spectroscopic...
Abstract: Lithium metal batteries, which use lithium as the anode, have attracted tremendous research interest in recent years, owing to their high energy density and potential for future storage applications. Despite advantages such density, safety concerns short lifespan significantly impede practical applications transportation electronic devices. Tremendous efforts been devoted overcoming these problems, including materials design, interface modification, electrolyte engineering. Among...
Abstract High energy density lithium metal batteries (LMBs) have garnered significant research interests in the past decades. However, growth of dendrites and low Coulombic efficiency (CE) Li anode pose challenges for development LMBs. Herein, we report a triethyl orthoformate (TEOF)-based localized high-concentration electrolyte (LHCE) that facilitates highly reversible with dendrite-free deposition morphologies an average 99.1% 450 cycles. Mechanistic study reveal steric hindrance caused...
Confocal fluorescence imaging of fine structures the cell membrane is important for understanding their biofunctions but often neglected due to lack an effective method. Herein, we develop new amphiphilic rhodamine fluorescent probe RMGs in combination with basal this purpose. The probes show high signal-to-noise ratio and brightness low internalization rate, making them suitable substructures membrane. Using representative RMG3, not only observed pseudopodia intercellular nanotubes also...
Drug-induced liver injury (DILI) is the most common reason for post-marketing withdrawal of drugs. Poor understanding mechanisms DILI presents a large challenge in clinical diagnosis. Previous evidences indicate potential relationship between reactive nitrogen species (RNS) and DILI. Hence, we developed two specific probes, Golgi-HNO Mito-HNO, multicolored simultaneous situ imaging nitroxyl (HNO) Golgi apparatus mitochondria, respectively. We discovered significant rise HNO levels livers...
Abstract The complex growth behavior of lithium (Li) metal has posed significant challenges in gaining an understanding the operational mechanisms batteries. intricate composition and structure solid electrolyte interphase (SEI) have added layers difficulty characterizing dynamic electrochemical processes involved anodes. Real‐time observation Li particularly been challenging. Fortunately, atomic force microscopy (AFM) emerged as a powerful tool, offering invaluable situ nanoscale insights...
Golgi pH homeostasis affects many different biological processes, including glycosylation. Recent studies have demonstrated that transmembrane protein 165 (TMEM165) deficiency leads to glycosylation abnormalities by disturbing homeostasis. However, due the lack of specific tools measure in situ, evidence for TMEM165 involvement H+ transport apparatus is still absent. Herein, photoacoustic and fluorescent dual-mode probe CPH was developed ratiometric detection pH. proved accumulate reversibly...
Abstract Metallene is considered as an emerging family of electrocatalysts due to its atomically layered structure and unique surface stress. Here we propose a strategy modulate the Bader charge transfer (BCT) between Pd oxygenated intermediates via p ‐ d electronic interaction by introducing single‐atom ‐block metal (M=In, Sn, Pb, Bi) into metallene nanosheets towards efficient oxygen reduction reaction (ORR). X‐ray absorption photoelectron spectroscopy suggests that doping metals could...
The miniaturization and integration increment of silicon-based optoelectronic devices have placed greater demands on surface cleaning technologies. Carbon dioxide snow technology achieves through jets formed by the coexistence solid, liquid, gaseous phases CO<sub>2</sub> . Solid particles sublimate expand, impacting contaminants, causing them to detach from surface. effect liquid relies its ability dissolve organic pollutants adhesion force contaminants. Gaseous carries away dislodged This...
Quantifying the lipid composition of cellular droplets (LDs) in situ is challenging but crucial for understanding metabolic diseases. Here, we propose a fluorescence lifetime imaging method based on polarity-sensitive probe (LD660) analyzing LDs. The emits strong at 660 nm only apolar LD environments, with dielectric constants 2–4, and outperforms Nile red imaging. Importantly, LD660 increases incremental fraction cholesteryl ester neutral mixtures. Using microscopy LD660, imaged quantified...
Abstract NIR‐II fluorescence imaging has shown broad application prospects in life science because of its deeper tissue penetration and higher spatiotemporal resolution. Developing fluorophores with special spectroscopic properties analytical functions become a cutting‐edge but challenging topic this field. Herein, series azulene‐based (called cyazulenes) adjustable cycloalkenes for applications is reported. Cyazulenes (CA965, CA985, CA1025) are constructed via the convenient coupling...
trans -Caffeic acid was used as a fluorescent probe for highly sensitive detection of laccase. Laccase contents in three grape juice samples with different fermentation levels and kinds mushroom extracts were determined.
Severe atmospheric haze caused by industrial pollution has severely affected human health and led to the increasing incidence of cardiopulmonary diseases, including pneumonia. Conventional methods for diagnosis pneumonia are complicated tedious, current clinical imaging techniques might cause organ injuries some extent. Therefore, an accurate, fast, intact method must be developed diagnose in early stages. In this study, we propose a new two-photon fluorescence probe, named as ASPC,...
We developed a photoacoustic and fluorescent dual-mode imaging probe, CCYS, for the detection of cysteine with high selectivity sensitivity in living system first time. By using we found that limited synthesis glutathione pulmonary fibrosis was not caused by deficiency.