- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Asthma and respiratory diseases
- Tuberculosis Research and Epidemiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Immune cells in cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Mycobacterium research and diagnosis
- Immune Response and Inflammation
- Immune Cell Function and Interaction
- Allergic Rhinitis and Sensitization
- Pulmonary Hypertension Research and Treatments
- Adipose Tissue and Metabolism
- S100 Proteins and Annexins
- Immunodeficiency and Autoimmune Disorders
- Neonatal Respiratory Health Research
- Systemic Sclerosis and Related Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Regulation of Appetite and Obesity
- Vasculitis and related conditions
- Sarcoidosis and Beryllium Toxicity Research
- Diagnosis and treatment of tuberculosis
- Viral gastroenteritis research and epidemiology
- Food Allergy and Anaphylaxis Research
- Genomics and Rare Diseases
- Blood disorders and treatments
Medical University of Warsaw
2015-2024
Postgraduate School of Molecular Medicine
2016
Gdańsk Medical University
2016
University of Warsaw
2015
Institute of Psychiatry and Neurology
2014
Ege University
2014
Carol Davila University of Medicine and Pharmacy
2014
Children's Memorial Health Institute
2014
Centralny Szpital Kliniczny
2011
Instytut Gruźlicy i Chorób Płuc
1997-2008
Neutrophils are one of the first cells to arrive at site infection, where they apply several strategies kill pathogens: degranulation, respiratory burst, phagocytosis, and release neutrophil extracellular traps (NETs). Antibiotics have an immunomodulating effect, can influence properties numerous immune cells, including neutrophils. The aim this study was investigate effects azithromycin chloramphenicol on apoptosis, NETs by were isolated from healthy donors density-gradient centrifugation...
Abstract Studies on neutrophil extracellular traps ( NET s) are challenging as neutrophils live shortly and easily become activated. Thus, availability of a cell line model closely resembling the functions peripheral blood would be advantageous. Our purpose was to find compound that most effectively differentiates human promyelocytic leukemia (HL‐60) cells toward granulocyte‐like able release s. HL ‐60 were differentiated with all‐trans retinoic acid ATRA ), dimethyl sulfoxide DMSO ) or...
Despite great interest, the mechanism of neutrophil extracellular traps (NETs) release is not fully understood and some aspects this process, e.g. role reactive nitrogen species (RNS), still remain unclear. Therefore, our aim was to investigate mechanisms underlying RNS-induced formation NETs contribution RNS triggered by various physiological synthetic stimuli. The involvement in studied primary human neutrophils differentiated promyelocytic leukemia cells (HL-60 cells). (peroxynitrite...
Since the SARS-CoV-2 outbreak, many countries have introduced measures to limit transmission. The data based on ICD-10 codes of lower respiratory tract infections and microbiological analysis gastrointestinal were collected. retrospective five-year medical records revealed a substantial decrease in during pandemic year (from April 2020 March 2021). We noted an 81% decline LRTI-associated hospital admissions mean 1170 per previous four years 225 between through According analysis, there 100%,...
Atopic allergy is among the immune tolerance-related disorders resulting from a failure of regulatory network. Regulatory T cells (Tregs) play leading role in development homeostasis system. The aim this study was to determine Tregs pathogenesis atopic diseases children by exploring relationship between Treg frequency, activation markers and clinical manifestations disease.Twenty allergic 50 healthy were enrolled study. Peripheral blood mononuclear stained with monoclonal antibodies...