A5023775184- Genetic Associations and Epidemiology
- Cancer-related molecular mechanisms research
- Venous Thromboembolism Diagnosis and Management
- Blood Coagulation and Thrombosis Mechanisms
- MicroRNA in disease regulation
- Statistics Education and Methodologies
- RNA modifications and cancer
- Genetics and Plant Breeding
- Legume Nitrogen Fixing Symbiosis
- Genetic Mapping and Diversity in Plants and Animals
- Agricultural pest management studies
- Comics and Graphic Narratives
- Decision-Making and Behavioral Economics
- Retinal Diseases and Treatments
- Genetic and Environmental Crop Studies
- RNA Research and Splicing
- Nutrition, Genetics, and Disease
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Gene expression and cancer classification
- Bioinformatics and Genomic Networks
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Epigenetics and DNA Methylation
- Plant Pathogenic Bacteria Studies
Institute for Sustainable Development
2020
James Cook University Singapore
2019
Université Claude Bernard Lyon 1
2016
Centre National de la Recherche Scientifique
2016
Laboratoire de Microbiologie, Adaptation et Pathogénie
2016
Sorbonne Université
2011-2014
Unité de recherche sur les maladies cardiovasculaires et métaboliques
2014
Inserm
2011-2014
Université Paris Cité
2014
Fondation pour l’innovation en Cadiométabolisme et Nutrition
2013-2014
Background Venous Thrombosis (VT) is a common multifactorial disease associated with major public health burden. Genetics factors are known to contribute the susceptibility of but how many genes involved and their contribution VT risk still remain obscure. We aimed identify genetic variants risk. Methodology/Principal Findings conducted genome-wide association study (GWAS) based on 551,141 SNPs genotyped in 1,542 cases 1,110 controls. Twelve reached significance level 2.0×10−8 encompassed...
Cowpea [Vigna unguiculata (L.) Walp] is one of the important climate-resilient legume crops for food and nutrition security in sub-Saharan Africa. Ethiopia believed to harbor high cowpea genetic diversity, but this has not yet been efficiently characterized exploited breeding. The objective study was evaluate extent pattern diversity 357 accestions comprising landraces (87%), breeding lines (11%) released varieties (2%), using single nucleotide polymorphism markers. overall gene...
Dickeya species are soft rot disease-causing bacterial plant pathogens and an emerging agricultural threat in Europe. Environmental modulation of gene expression is critical for dadantii pathogenesis. While the bacterium uses various environmental cues to distinguish between its habitats, intricate transcriptional control system coordinating virulence genes ensures efficient infection. Understanding this behaviour requires a detailed knowledge patterns under wide range conditions, which...
We aimed to assess whether pri-miRNA SNPs (miSNPs) could influence monocyte gene expression, either through marginal association or by interacting with polymorphisms located in 3'UTR regions (3utrSNPs). then conducted a genome-wide search for miSNPs effects and pairwise × 3utrSNPs interactions sample of 1,467 individuals which expression genotype data were available. Statistical associations that survived multiple testing correction tested replication an independent 758 both data. In...
Principal Component analysis (PCA) is a useful statistical technique that commonly used for multivariate of correlated variables. It usually applied as dimension reduction method: the top principal components (PCs) explaining most total variance are tested association with predictor interest, and remaining PCs ignored. This strategy has been widely in genetic epidemiology, however some its aspects not well appreciated context single nucleotide polymorphisms (SNPs) testing. In this study, we...
We aimed to assess whether pri-miRNA SNPs (miSNPs) could influence monocyte gene expression, either through marginal association or by interacting with polymorphisms located in 3'UTR regions (3utrSNPs).We then conducted a genome-wide search for miSNPs effects and pairwise 6 3utrSNPs interactions sample of 1,467 individuals which expression genotype data were available.Statistical associations that survived multiple testing correction tested replication an independent 758 both data.In...