A5017806767- Fungal Biology and Applications
- Fungal and yeast genetics research
- Mycorrhizal Fungi and Plant Interactions
- Wastewater Treatment and Nitrogen Removal
- Single-cell and spatial transcriptomics
- Neurobiology and Insect Physiology Research
- Polysaccharides and Plant Cell Walls
- Entomopathogenic Microorganisms in Pest Control
- Medicinal Plants and Bioactive Compounds
- Insect Resistance and Genetics
- Meat and Animal Product Quality
- Biocrusts and Microbial Ecology
- Protein Hydrolysis and Bioactive Peptides
- Microbial metabolism and enzyme function
- Microbial Natural Products and Biosynthesis
- Microbial Metabolism and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Insect symbiosis and bacterial influences
- Methane Hydrates and Related Phenomena
- Membrane Separation Technologies
- Immune Response and Inflammation
- Animal Nutrition and Physiology
- Genetics, Aging, and Longevity in Model Organisms
- Plant and Biological Electrophysiology Studies
- Slime Mold and Myxomycetes Research
Nanjing Agricultural University
2016-2025
Ministry of Agriculture and Rural Affairs
2020-2025
Hebei University of Environmental Engineering
2022-2024
Zhejiang Entry-Exit Inspection and Quarantine Bureau
2024
Ministry of Agriculture
2017-2023
Biogen (United States)
2021-2023
Shanghai Jiao Tong University
2023
Shenzhen University
2023
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2023
Anhui Agricultural University
2023
Arabinogalactan-proteins (AGPs) that bind to @-glycosyl Yariv antigens have been purified from the culture medium and plasma membrane of "Paul's Scarlet" rose cells.Starting or vesicles prepared by aqueous twophase partitioning, purification procedure involved antigen-induced precipitation subsequent chromatographic steps.Two fractions, AGP-(a) AGP-(b), were obtained medium, one AGP fraction was membrane.The glycosyl compositions all three fractions dominated arabinosyl galactosyl residues...
Nanofiltration concentration leachate is a high organic wastewater with low biodegradability and toxicity. To explore the feasibility of combined Heat/UV activated persulfate process on nanofiltration concentrated leachate, effects concentration, initial solution pH before reaction, UV-lamp power reaction temperature removal pollutant were systematically investigated. Results indicated that maximum rate chemical oxygen demand (COD), ammonia-nitrogen (NH3-N) absorbance matter under UV light...
Abstract Autoantibodies are a hallmark of numerous neurological disorders, including multiple sclerosis, autoimmune encephalitides and neuromyelitis optica. Whilst well understood in peripheral myeloid cells, the pathophysiological significance autoantibody-induced Fc receptor signalling microglia remains unknown, part due to lack robust vivo model. Moreover, application therapeutic antibodies for neurodegenerative disease also highlights importance understanding microglia. Here, we describe...
Bck1, Mkk1 and Slt2 are three mitogen-activated protein (MAP) kinases constituting cell wall integrity (CWI) pathway that may control multi-stress responses via crosstalk with high-osmolarity glycerol (HOG) in budding yeast. In this study, orthologues Beauveria bassiana were confirmed as the three-module cascade essential for CWI because impairment occurred hyphae conidia of Δbck1, Δmkk1 Δslt2 examined multiple experiments. Strikingly, all deletion mutants became more sensitive to...
Ganoderma lucidum has high commercial value because it produces many active compounds, such as ganoderic acids (GAs). Salicylic acid (SA) was previously reported to induce the biosynthesis of GA in G. lucidum. In this study, we found that SA induces by increasing ROS production, and further research NADPH oxidase-silenced strains exhibited a partial reduction response SA, resulting induction increased production. Furthermore, localization shows mitochondria are sources production treatment....
ABSTRACT We previously reported that high temperature impacts ganoderic acid (GA) biosynthesis in Ganoderma lucidum via Ca 2+ . Therefore, to further understand the signal-regulating network of organism's response heat stress (HS), we examined role nitric oxide (NO) under HS. After HS treatment, NO level was significantly increased by 120% compared control conditions. The application a scavenger resulted 25% increase GA with found sample treated only Additionally, donor 30% lower content...
Summary Cellulose is a by‐product of agricultural production and an abundant waste. As carbon source, cellulose can be degraded utilized by fungi. Carbon sources, which act as nutrients, not only provide energy but also serve regulators gene expression, metabolism growth, through various signalling networks that enable cells to sense adapt varying environmental conditions. Nutrient‐sensing pathways prioritize the use preferred sources regulate cellulose‐degrading enzymes when necessary....
Flammulina filiformis, previously known as Asian velutipes, is one of the most commercially important edible fungi, with nutritional value and medicinal properties worldwide. However, precision genome editing using CRISPR/Cas9, which a revolutionary technology provides powerful tool for molecular breeding, has not been established in F. filiformis. Here, plasmids harboring expression cassettes Basidiomycete codon-optimized Cas9 dual sgRNAs targeting pyrG under control gpd promoter FfU6...
ABSTRACT Macrophages are among the most sensitive targets of bacterial endotoxin (LPS), responding to minute amounts LPS by releasing a battery inflammatory mediators. Transfection macrophages with secretory leukocyte protease inhibitor (SLPI) renders these cells refractory stimulation. Here we show that uptake from soluble CD14 (sCD14)-LPS complexes SLPI-overexpressing was only 50% seen in control cells. SLPI transfectants and mock did not differ surface expression or CD18. We show,...
Summary Some model fungi have three or four proteins with each vectoring a single cell W all S tress‐responsive C omponent ( WSC ) domain at N ‐terminus. In this study, five proteins, only in ‐terminal, central even ‐terminal region, were found B eauveria bassiana , filamentous fungal entomopathogen, and named Wsc1A–1E due to the singularity. Four of them lack either transmembrane conserved signature sequence DXXD compared homologues fungi. Intriguingly, eGFP ‐tagged fusion evidently...