A5100755884- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Hemodynamic Monitoring and Therapy
- Respiratory Support and Mechanisms
- Anesthesia and Neurotoxicity Research
- Ultrasound in Clinical Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- Health and Wellbeing Research
- Diverse Approaches in Healthcare and Education Studies
- Intensive Care Unit Cognitive Disorders
- Central Venous Catheters and Hemodialysis
- Non-Invasive Vital Sign Monitoring
- Cardiac Arrest and Resuscitation
- Vascular Procedures and Complications
- Anesthesia and Pain Management
- Congenital Heart Disease Studies
- Renal function and acid-base balance
- Consumer Perception and Purchasing Behavior
- Neonatal Respiratory Health Research
- Foreign Body Medical Cases
- Healthcare Education and Workforce Issues
- Intracerebral and Subarachnoid Hemorrhage Research
- Renal Diseases and Glomerulopathies
- Neonatal and fetal brain pathology
Seoul National University Hospital
2016-2025
National University College
2018-2024
Seoul National University
2006-2023
New Generation University College
2018-2022
Weatherford College
2022
Tokyo Metropolitan Children's Medical Center
2022
Wonkwang University
2014-2022
National Cancer Registration Service
2022
Dong-A University
2021
Baylor College of Medicine
2020
Astrocytic glutamate transporter protein, GLT-1 (EAAT2), recovers extracellular and ensures that neurons are protected from excess stimulation. Recently, beta-lactam antibiotics, like ceftriaxone (CTX), were reported to induce the upregulation of GLT-1. Here, we investigated ischemic tolerance induction by CTX in an experimental model focal cerebral ischemia.CTX (200 mg/kg per day, IP) was administered for 5 consecutive days before transient ischemia, which induced intraluminal thread...
Acute kidney injury (AKI) after pediatric cardiac surgery is associated with high morbidity and mortality. Modifiable risk factors for postoperative AKI including perioperative anesthesia-related parameters were assessed. The authors conducted a single-center, retrospective cohort study of 220 patients (aged 10 days to 19 years) who underwent congenital between January December 2012. incidence within 7 postoperatively was determined using the Kidney Disease: Improving Global Outcomes (KDIGO)...
Summary Atelectasis occurs in the majority of children undergoing general anaesthesia. Lung ultrasound has shown reliable sensitivity and specificity for diagnosing anaesthesia‐induced atelectasis. We assessed effects a recruitment manoeuvre on atelectasis using lung infants Forty infants, randomly allocated to either group or control group, received volume‐controlled ventilation with 5 cmH 2 O positive end‐expiratory pressure. examination was performed twice each patient, first minute after...
Estrogen plus progestin therapy increases both mammographic density and breast cancer incidence. Whether change associated with estrogen initiation predicts risk is unknown. We conducted an ancillary nested case-control study within the Women's Health Initiative trial that randomly assigned postmenopausal women to daily conjugated equine 0.625 mg medroxyprogesterone acetate 2.5 or placebo. Mammographic was assessed from mammograms taken prior one year after random assignment for 174 who...
Perioperative ventilatory strategies for lung protection in children are underexplored. This study evaluated the effects of protective ventilation (LPV) on postoperative clinical outcomes requiring one-lung (OLV) pulmonary resection.Children age ≤5 yr scheduled video-assisted thoracoscopic lobectomy or segmentectomy were randomly assigned to LPV control ventilation. For LPV, tidal volume (VT) was 6 ml kg-1 during two-lung (TLV(VT)), 4 OLV, with cm H2O PEEP maintained throughout. In group,...
Angiotensin II exerts its central nervous system effects primarily via receptors AT1 and AT2, it participates in the pathogenesis of ischemia AT1. The selective receptor blocker (ARB) is used hypertension treatment, a variety pleiotropic effects, including antioxidative, antiapoptotic, anti-inflammatory effects. In this study, we investigated therapeutic effect ARB telmisartan experimental intracerebral hemorrhage (ICH) normotensive rats. ICH was induced collagenase infusion or autologous...
Glutamate is accumulated in abundance during the early period of experimental hematoma, and activation N-methyl-D-aspartate (NMDA) receptors by glutamate can result an influx calcium neuronal death cases intracerebral hemorrhage (ICH). Memantine, which known to be a moderate-affinity, uncompetitive, NMDA receptor antagonist, was investigated with regard its ability block overstimulation tissue plasminogen activator (tPA)/urokinase (uPA)/matrix metalloproteinase (MMP)-9 modulation ICH....
BACKGROUND Even with ultrasound guidance, arterial cannulation in children can be challenging. OBJECTIVE To compare the short-axis/out-of-plane (SAX) long-axis/in-plane (LAX) technique for ultrasound-guided children. DESIGN A randomised controlled trial. SETTING tertiary university hospital, from 5 January 2015 to 21 April 2015. PATIENTS 101 children, American Society of Anesthesiologists’ physical status 1 or 2 and younger than years age. INTERVENTIONS All were into one four groups...
Abstract Background Pediatric cardiac patients are at risk for perioperative respiratory insufficiency. The objective of this study was to assess the utility lung ultrasound examination in pediatric surgery. Methods In randomized, controlled trial, children (5 yr old or younger) undergoing surgery were allocated into a control (n = 61) intervention group. group received only examinations end and 6 12 h after an ultrasound-guided recruitment maneuver depending on findings inducing anesthesia,...
Hierarchical Cu pillar electrodes have shown enhanced electrochemical performance for CO<sub>2</sub> reduction due to their increased surface area and controlled lattice property.
Background and PurposezzHemispherectomy reportedly produces remarkable results in terms of seizure outcome quality life for medically intractable hemispheric epilepsy children.We reviewed the neuroradiologic findings, pathologic characteristics, clinical long-term outcomes pediatric patients following a disconnection.MethodszzWe retrospectively studied 12 children (8 males) who underwent hemispherectomy at Asan Medical Center between 1997 2005.Clinical, EEG, neuroradiological, surgical data...
Abstract Background We evaluated the posterior tibial artery as an alternative arterial cannulation site to radial in small children. Methods A two-stage study was conducted. First, we anatomical characteristics of compared with and dorsalis pedis arteries. Next, a parallel-arm single-blind randomized controlled initial success rate ultrasound-guided among three arteries primary outcome. Results Sixty patients were analyzed observational study. The diameter (1.5 ± 0.2 mm) similar that larger...
Background Pediatric radial artery cannulation is challenging because of the small vessel size. Nitroglycerin a potent vasodilator and facilitates by increasing internal diameter preventing vasospasm in adult patients. The authors hypothesize that subcutaneous nitroglycerin injection will improve success rate pediatric cannulation. Methods This double-blind, randomized, controlled, single-center study enrolled patients (n = 113, age less than 2 yr) requiring during general anesthesia....
BACKGROUND Ultrasound-guided alveolar recruitment, regardless of the technique, could be more effective because it facilitates real-time monitoring expansion collapsed alveoli. OBJECTIVES To evaluate and compare effects an ultrasound-guided lung recruitment manoeuvre with those a conventional on occurrence postoperative atelectasis clinical outcomes in children. DESIGN A randomised controlled trial. SETTING Tertiary children's hospital. PATIENTS Children aged 6 years or less. INTERVENTION...
Abstract Background Pediatric patients undergoing cardiovascular interventions outside the operating room are at high risk of perioperative hypothermia. We aimed to compare effects upper body and full underbody forced-air warming blankets on time-weighted deviation esophageal temperature target range (36.5–37.5 °C) during general anesthesia. Methods In this randomized controlled study, 88 children (age < 15 years) scheduled for elective under anesthesia were randomly assigned ( n = 44) or...
Abstract Hemoglobin A 1c (HbA ) is an indicator of long‐term glycemic control. The purpose this study was to determine whether habitual snoring associated with increased HbA levels in non‐obese and normoglycemic middle‐aged men women. total 6981 subjects (3362 3619 women) aged 40–69 years from the Korean Health Genome Study were examined for study. Each participant received a comprehensive physical examination as well set questions pertaining demographic characteristics frequency. Habitual...
Purpose To identify the correlation of pre- and postablation imaging features with pain relief, intensity, patient mood after radiofrequency (RF) ablation solitary painful osseous metastases. Materials Methods This prospective, multicenter group trial was approved by each institutional review board. Participants were enrolled between November 1, 2001, April 6, 2006. Written informed consent obtained from all subjects, confidentiality protocols followed in compliance HIPAA. Computed...