A5101890942- Chemokine receptors and signaling
- Gastric Cancer Management and Outcomes
- Rare-earth and actinide compounds
- Cytokine Signaling Pathways and Interactions
- Peptidase Inhibition and Analysis
- Physics of Superconductivity and Magnetism
- Cellular transport and secretion
- Lung Cancer Treatments and Mutations
- Gastrointestinal Tumor Research and Treatment
- Biomarkers in Disease Mechanisms
- Multiple Myeloma Research and Treatments
- Bone health and treatments
- Medicinal Plant Pharmacodynamics Research
- Medieval European Literature and History
- Vascular Malformations and Hemangiomas
- Tumors and Oncological Cases
- Protein Structure and Dynamics
- Bone Metabolism and Diseases
- Computational Drug Discovery Methods
- Cancer Cells and Metastasis
- Advanced Condensed Matter Physics
- Vascular Malformations Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Crystal Structures and Properties
- Iron-based superconductors research
Nanjing University
2007-2020
Nanjing General Hospital of Nanjing Military Command
2020
Hainan General Hospital
2019
Peking University
2013-2016
Beijing Jishuitan Hospital
2015
Yantai University
2011
Tsinghua University
2004
// Wanqiong Yuan 1 , Ting Li Xiaoning Mo Xiaolin Wang Baocai Liu Wenyan Yu Su Lan Xu Wenling Han Peking University Center for Human Disease Genomics, Department of Immunology, Key Laboratory Medical Ministry Health, School Basic Sciences, Health Science Center, Beijing 100191, China Correspondence to: Han, e-mail: hanwl@bjmu.edu.cn Keywords: CMTM3, gastric cancer, EMT, metastasis, STAT3 Received: September 26, 2015 Accepted: March 28, 2016 Published: April 18, ABSTRACT CMTM3 (CKLF-like...
We report $^{75}\mathrm{As}$ nuclear magnetic resonance studies on a very clean hole-doped single-crystal Ba${}_{0.68}$K${}_{0.32}$Fe${}_{2}$As${}_{2}$ (${T}_{\mathrm{c}}=38.5$ K). The spin-lattice relaxation rate $1/{T}_{1}$ shows an exponential decrease below $T\ensuremath{\simeq}0.45{T}_{\mathrm{c}}$ down to $T\ensuremath{\simeq}0.11{T}_{\mathrm{c}}$, which indicates fully opened energy gap. From the ratio $({T}_{1}){}_{c}/({T}_{1}){}_{a}$, where $a$ and $c$ denote crystal directions, we...
// Baocai Liu 1, * , Yu Su 2, Ting Li 1 Wanqiong Yuan Xiaoning Mo Henan 3 Qihua He 4 Dalong Ma Wenling Han Center for Human Disease Genomics, Department of Immunology, Key Laboratory Medical Ministry Health, School Basic Sciences, Peking University, Beijing, China 2 Clinical Laboratory, Beijing Jishuitan Hospital, University People's and Health Analysis Center, These authors have contributed equally to this work Correspondence to: Han, e-mail: hanwl@bjmu.edu.cn Keywords: NSCLC, CMTM7, EGFR,...
The CKLF-like MARVEL transmembrane domain containing 3 (CMTM3) gene is a novel tumor suppressor with frequent epigenetic inactivation. In this study, we showed the role played by CMTM3 in gastric cancer cells as gene, and examined correlation between expression clinicopathological parameters using immunohistochemistry patients different pathological stages (n = 350). We found that was reduced or silenced regulation cell lines, dramatically downregulated primary tissues. Restoration of...
A number of experiments suggested that metal binding can promote the aggregation amyloid-β peptide. In this work, effects zinc on conformational distributions full length peptide are investigated basis extensive molecular dynamics simulations. By comparing apo-peptide and holo-peptide, we show affect distribution monomer dramatically. Compared with apo-peptide, holo-peptide samples more β-strand conformation for central hydrophobic cluster 17−21. Meanwhile, formation probabilities salt...
Background CKLF-like MARVEL transmembrane domain-containing 7 ( CMTM7 ) located at 3p22.3, is a frequent deletion site and tumor suppressor gene (TSG) locus in many cancer, which suggests may be potential TSG. The aim of this study was to investigate the correlations expression survival rate patients with non-small-cell lung cancer (NSCLC). Methods Surgical specimens 180 cases pathologically confirmed NSCLC were grouped into 18 tissue microarray slides. these detected by immunohistochemistry...
A phase II study was conducted to evaluate the safety and efficacy of preoperative, intra-arterial perfusion epirubicin, etoposide, oxaliplatin combined with oral chemotherapy S-1 (SEEOX) for treatment type 4 gastric cancer.A single-center, single-arm trial on 36 patients histologically proven cancer without distant peritoneal or organ metastasis. Patients received 3, 21-day courses SEEOX preoperative chemotherapy. The primary endpoint overall survival (OS) secondary outcomes assessed were...
A strong nonmagnetic impurity can induce a resonance state in the d-wave superconducting state. As far as magnetic properties are concerned, this behaves effectively like free moment. It leads to Curie-Weiss-like susceptibility an intermediate temperature regime below $T_{c}$. From susceptibility, effective moment of is deduced and compared with experiments. The contribution account for main feature NMR spectra overdoped high-$T_c$ materials. In underdoped regime, from also substantial, but...
Tumor bone metastasis is one of the main causes treatment failure in tumor. Since tumor a complex process, exact etiopathogenesis has not been clarified. Recent studies demonstrated that osteoprotegerin/receptor activator NF-κB ligand/receptor (OPG/RANKL/RANK) system plays an important role during development and progression metastasis. In this review, research progress OPG/RANKL/RANK system, including biological functions,the microenvironment regulation, detection method,the diagnosis will...