A5082627499- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Mycobacterium research and diagnosis
- Eosinophilic Esophagitis
- Immune Response and Inflammation
- Inflammatory mediators and NSAID effects
- Clinical Nutrition and Gastroenterology
- Lung Cancer Diagnosis and Treatment
- Diverticular Disease and Complications
- Barrier Structure and Function Studies
- Gastroesophageal reflux and treatments
- Photodynamic Therapy Research Studies
- Pelvic floor disorders treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Non-Invasive Vital Sign Monitoring
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- IL-33, ST2, and ILC Pathways
- Microscopic Colitis
- Gastrointestinal motility and disorders
- Immune cells in cancer
- Veterinary medicine and infectious diseases
Community Medical Center
2022
Kyoto Prefectural University of Medicine
2014-2021
Kyoto first Red Cross hospital
2013
Linked color imaging (LCI) is a new image-enhanced endoscopy technique using laser light source to enhance slight differences in mucosal color. The aim of this study was compare the usefulness LCI and conventional white (WLI) for diagnosing Helicobacter pylori (H. pylori).We retrospectively analyzed images from 60 patients examined with WLI between October 2013 May 2014. Thirty had H. infections, other thirty tested negative after eradication therapy. Four endoscopists evaluated 2 types...
Background and study aim This aimed to assess the safety feasibility of endoscopic submucosal dissection (ESD) using a scissors‐type knife with prophylactic closure over‐the‐scope clip (OTSC) for superficial non‐ampullary duodenal epithelial tumors (SNADETs). Patients methods Consecutive patients who underwent ESD SNADETs >10 mm between January 2009 July 2019 were retrospectively enrolled. We performed either needle‐type (Flush Knife‐ESD) or (Clutch Cutter‐ESD). Mucosal defects...
Background/Aims . The aim of this study was to evaluate the endoscopic recognition esophageal squamous cell carcinoma (ESCC) using four different methods (Olympus white light imaging (O-WLI), Fujifilm (F-WLI), narrow band (NBI), and blue laser imaging- (BLI-) bright). Methods. We retrospectively analyzed 25 superficial ESCCs that had been examined methods. Subjective evaluation provided by three endoscopists as a ranking score (RS) each image based on ease detection cancerous area. For...
Early-stage gastric cancer (EGC) is detected even after successful Helicobacter pylori eradication. This study aimed at clarifying the clinicopathological characteristics of EGC H. eradication.This retrospective analyzed 57 cases eradication and resected endoscopically Kyoto Prefectural University Medicine, between January 2009 June 2014. Clinicopathological findings (H. pylori-eradicated group) were investigated, compared with those in active infection same period pylori-positive...
Magnifying endoscopy with blue laser imaging (ME-BLI) for diagnosis of early gastric cancer (EGC) is as effective magnifying narrow-band (ME-NBI). However, there are different EGCs in microstructure visualization between ME-BLI and ME-NBI. This study aimed to clarify the pathological features EGCs, which was ME-NBI ME-BLI. were classified into groups A (irregular microsurface pattern (MSP) absent MSP ME-NBI), B two modalities), or C (absent according vessel plus surface classification. We...
Mucin is produced and secreted by epithelial goblet cells a key component of the innate immune system, acting as barrier in intestinal tract. However, no studies have been conducted investigating increase mucin secretion to enhance function. The present study investigated whether rebamipide (Reb) acts secretagogue underlying mechanisms involved, thereby focusing on effect cells. LS174T cell line was used cell‑like Using Reb‑treated cells, level content assessed periodic acid‑Schiff (PAS)...
Background/Aims: The aim of this study was to evaluate the diagnostic accuracy magnifying narrow-band imaging (M-NBI) with histopathological confirmation in identifying demarcation line (DL) early gastric cancer (EGC). Methods: EGCs resected by endoscopic submucosal dissection after DL using M-NBI following were included. After determining for entire EGC lesion M-NBI, at least 4 biopsies taken from non-cancerous tissues outside confirmation. Results: A total 330 analyzed study. rate...
The eradication rate of Helicobacter pylori (H. pylori) with proton pump inhibitors, amoxicillin, and clarithromycin has reportedly decreased. Some studies have found probiotics to be useful in eradicating H. pylori, but these effects not been sufficiently investigated. We aimed elucidate the role infection. Patients our hospital infection that received standard treatment from January 2015 December 2016 were retrospectively evaluated (n = 468). They divided into three groups based on their...
Background: Vonoprazan (VPZ) has the potential to prevent delayed bleeding and promote ulcer healing after endoscopic submucosal dissection (ESD) similar proton pump inhibitors (PPIs). Objective: We aimed evaluate outcomes of VPZ-treated patients ESD compared efficacy feasibility in preventing a an artificial between VPZ PPI therapies. Methods: This was prospective, observation study 11 Japanese medical institutions. enrolled evaluated 223 who underwent gastric followed by treatment (VPZ...
Esophagogastroduodenoscopy (EGD) is important for the detection of curable gastric cancer (GC). However, there are no appropriate surveillance data during routine endoscopic inspections. This study aimed to clarify risk factors pT1b or deeper GC endoscopy.This was a retrospective, multicenter, cross-sectional conducted in 15 Japanese hospitals. We retrospectively analyzed patients with who had previously undergone endoscopy at each institution from January 2014 March 2020. Patients...
OBJECTIVES In this study we aimed to verify a real‐time trans‐epithelial electrical resistance ( TEER) monitoring system in C aco‐2 monolayer and investigate the therapeutic effect of partially hydrolyzed guar gum PHGG ), dietary fiber, against interferon IFN )‐γ‐induced intestinal barrier dysfunction using system. METHODS We measured TEER evaluated epithelial paracellular permeability fluorescein isothiocyanate‐conjugated dextran (4 kDa; FD 4) monolayers treated with ‐γ for 48 h. The...
<b><i>Background:</i></b> Accurate diagnosis of the demarcation line (DL) gastric tumors is essential for curative complete resection by endoscopic submucosal dissection (ESD). It controversial to perform only magnifying endoscopy diagnosing DL prior ESD. This study aimed evaluate diagnostic accuracy adenomas and well-differentiated adenocarcinomas using blue laser imaging (M-BLI) compared with that both M-BLI biopsy confirmation....
Studies have reported the feasibility of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) in elderly people with respect to both short- and long-term outcomes. As population society increases, requirement managing super-elderly patients aged ≥85 years EGC will also increase. This study aims identify clinical outcomes ESD T1N0 years.A total 370 consecutive who were managed 11 institutions reviewed retrospectively. On basis treatment strategy, we compared overall survival...
Approximately 90% of all idiopathic perianal abscesses occur due to infection the cryptoglobular glands (1,2) .The purpose drainage is decompress abscess cavity in order prevent progressive inflammation, which could result potentially lifethreatening complications (3) .A 31-year-old Japanese man was admitted our hospital with severe anal pain and high fever.Computed tomography identified a fluid collections near right buttock (FIGURE 1).A surgical incision made from buttock; however, poor...
Background/Aims: Gastric-type differentiated adenocarcinoma (GDA) of the stomach is a rare variant gastric cancer that highly infiltrating and exhibits early metastasis. However, endoscopic pathological features “early-stage” GDA remain unknown. The aim this study to characterize early-stage GDA. Methods: We retrospectively enrolled 479 differentiated-type cases who underwent submucosal dissection (ESD). were selected based on morphology immunohistochemistry. Clinicopathological data...