- Molecular Sensors and Ion Detection
- Sulfur Compounds in Biology
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Analytical Chemistry and Sensors
- Nitric Oxide and Endothelin Effects
- Metal-Organic Frameworks: Synthesis and Applications
- Electrochemical sensors and biosensors
- Sulfur-Based Synthesis Techniques
- Lanthanide and Transition Metal Complexes
- Advanced Chemical Sensor Technologies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Nanoplatforms for cancer theranostics
- Nanocluster Synthesis and Applications
- Catalytic C–H Functionalization Methods
- Redox biology and oxidative stress
- Advanced Nanomaterials in Catalysis
- Electrochemical Analysis and Applications
- Metal complexes synthesis and properties
- Analytical chemistry methods development
- Crystallization and Solubility Studies
- Synthesis of Indole Derivatives
- Inflammatory mediators and NSAID effects
- Odor and Emission Control Technologies
- X-ray Diffraction in Crystallography
University of Science and Technology Liaoning
2016-2025
Educational Department of Liaoning Province
2016-2025
Capital Medical University
2024
Chuzhou University
2023
Anhui Medical University
2023
Anshan Hospital
2014-2020
North China University of Science and Technology
2018
Dalian University
2008-2016
Dalian University of Technology
2008-2016
State Key Laboratory of Fine Chemicals
2016
We report the development of a red-emitting fluorescence probe (XDS) for hydrogen sulfide (H2S) detection in biosystems, real-world food samples, and application this monitoring H2S production during spoilage. The XDS is developed by coupling coumarin derivative to rhodanic-CN through responsive CC bond. Remarkable quenching observed as result response H2S. Semi-quantitative three water two beer samples spoilage real-time "naked-eye" smartphone colorimetric analysis are then achieved using...
Diagnosis and early assessment of the treatment response rheumatoid arthritis (RA) necessitates a reliable bioanalytical method for rapid, sensitive, specific detection hypochlorous acid (HOCl) biomarker in inflammatory diseases. Herein, two fluorescence probes, Probe-1 Probe-2 are developed quantitative monitoring visualization response-related HOCl levels vitro vivo. In presence HOCl, "OFF-ON" is obtained both probes as result HOCl-triggered C=N bond cleavage reaction. feature rapid (<4...
Abstract An inorganic–organic silica material (SBA–P2), prepared by immobilization of the 1,8‐naphthalimide‐based receptor P2 within channels mesoporous SBA‐15, is characterized transmission electron microscopy and several spectroscopic methods. SBA–P2 features a high affinity Cu 2+ ‐specific fluorescence response in aqueous solution with detection limit for ca. 0.65 ppb (10 × 10 −9 M ) under optimized conditions. It can extract from only trace amounts remaining. Through isolating toxic ions...
Abstract Because of the importance HONO as a radical reservoir, consistent and accurate measurements its concentration are needed. As part SHARP (Study Houston Atmospheric Radical Precursors), time series were obtained by six different measurement techniques on roof Moody Tower at University Houston. Techniques used long path differential optical absorption spectroscopy (DOAS), stripping coil‐visible photometry (SC‐AP), (LOPAP ® ), mist chamber/ion chromatography (MC‐IC), quantum...
Abstract Responsive nanoprobes play an important role in bioassay and bioimaging, early diagnosis of diseases treatment monitoring. Herein, a upconversional nanoparticle (UCNP)‐based nanoprobe, Ru@UCNPs, for specific sensing imaging hypochlorous acid (HOCl) is reported. This Ru@UCNP nanoprobe consists two functional components,, i.e., NaYF 4 :Yb, Tm UCNPs that can convert near infrared light‐to‐visible light as the energy donor, HOCl‐responsive ruthenium(II) complex [Ru(bpy) 2 (DNCH‐bpy)](PF...
Emission of toxic gaseous sulfur dioxide (SO
Chemosensors play important roles in cation and anion recognition biological, industrial, environmental processes. Although many efforts have been made to develop artificial fluorescent receptors for Cu(2+) S(2-), their applications the detection bulk solutions are limited. In this work, we report a novel fluorescence chemosensor (NL) based on 7-nitrobenz-2-oxa-1,3-diazole (NBD) fluorophore quantification of S(2-) single intact cells. NL specifically binds presence other competing cations,...
An effective bioanalytical method for rapid, sensitive, specific, and in situ sensing of nitric oxide (NO) is the key further unveiling biological functions this gasotransmitter molecule vitro vivo. In contribution, a new fluorescence probe imaging NO live systems was developed. The probe, FP-NO, designed by exploring novel mechanism, i.e., rotation N–N single bond coumarin derivative. FP-NO prepared incorporating recognition unit, thiosemicarbazide moiety into fluorophore. weakly...
A renewable metal–organic-frameworks (MOFs)-polylactic acid (PLA) film was designed and prepared in order to remove malachite green (MG) waste water.
The development of new methods for rapid and effective detection bisulfite (HSO3–) in food samples imaging HSO3– intake animals is significant importance due to the key roles quality assurance community health. In this work, a responsive fluorescence probe, EQC, reported quantitative visualization animals. Upon addition HSO3–, UV–vis absorption red emission EQC were significantly decreased within 120 s. changes spectra rationalized by theoretical computations. proposed reaction mechanism...
Key roles of bisulfite (HSO3-) in food quality assurance and human health necessitate a reliable analytical method for rapid, sensitive, selective detection HSO3-. Herein, new red-emitting ratiometric fluorescence probe, BIQ, is reported sensitive HSO3- samples live animals. Probe BIQ recognizes via 1,4-nucleophilic addition reaction. As result this specific reaction, emission intensities at 625 475 nm are dramatically changed, allowing the model an aqueous solution. The obvious changes...
In this work, a phenothiazine-based fluorescent probe (PR) has been developed for the selective detection of hydrogen sulfide (H2S) in biosystems and monitoring H2S produced food spoilage process. The nucleophilic attack on CC double bond PRvia Michael addition interdicted ICT process to trigger 34-fold enhancement fluorescence emission. PR featured high selectivity sensitivity (1.8 μM), low cytotoxicity reliability at physiological pH. "Naked-eye" using was successfully accomplished....
Abstract Recent studies revealed that the increased level of hypochlorous acid (HOCl) may be deemed to one signs chronic inflammatory joint disease. Accordingly, development effective methods for rapid and accurate detection or monitoring HOCl in vivo is great significance further understanding role rheumatoid arthritis (RA). Herein, a ratiometric near‐infrared (NIR) fluorescent probe ( PTA ) was reported HOCl. In presence HOCl, electron‐rich S atom C=C double bond were oxidized sequence,...
We report the development of a new chromogenic and fluorogenic probe for detection HOCl in zebrafish, mice with arthritis environmental water samples.