A5081514536- Head and Neck Surgical Oncology
- Meningioma and schwannoma management
- Ear and Head Tumors
- Sinusitis and nasal conditions
- Cerebrospinal fluid and hydrocephalus
- TGF-β signaling in diseases
- Angiogenesis and VEGF in Cancer
- Tracheal and airway disorders
- Ear Surgery and Otitis Media
- Surgical Simulation and Training
- Pituitary Gland Disorders and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Allergic Rhinitis and Sensitization
- Craniofacial Disorders and Treatments
- Olfactory and Sensory Function Studies
- Head and Neck Cancer Studies
- Facial Trauma and Fracture Management
- Medical Imaging and Analysis
- Oropharyngeal Anatomy and Pathologies
- Nasal Surgery and Airway Studies
- Advanced Radiotherapy Techniques
- Metabolism, Diabetes, and Cancer
- Brain Metastases and Treatment
Emory University
2021-2025
University of North Carolina at Chapel Hill
2024-2025
Wake Forest University
2016-2017
East Carolina University
2012-2015
Jackson Memorial Hospital
2013
Vascular smooth muscle cell (VSMC) activation promotes a synthetic phenotype that underlies many vessel growth disorders. In this regard it has been suggested the metabolic sensor adenosine 5′-monophosphate-activated protein kinase (AMPK) significant antigrowth and antimetastatic properties may serve as viable therapeutic target. current study we hypothesized AMPK reduces neointima formation following balloon injury occurs through reduction in VSMC proliferation migration. Data reveal local...
Abstract Background Central compartment atopic disease (CCAD) is a variant of chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) characterized by polypoid changes the superior septum, middle (MT), and/or turbinates (ST). This study evaluates surgical outcomes in patients CCAD compared other CRSwNP subtypes. Methods Retrospective analysis was performed at Emory University from May 2012 to November 2019. Patients undergoing primary endoscopic sinus surgery (ESS) for CCAD,...
INTRODUCTION: We describe our preliminary investigation on microscopic real-time near-infrared indocyanine (NIR-ICG) fluorescence and white light overlay modality in anterior transpetrosal approaches for enhancing the intraoperative flow-dependent visualization of critical vascular structures. METHODS: used robotic microscope (ZEISS KINEVO 900Ò) built-in FLOW800 INFRARED800 functions with capabilities to provide simultaneous ocular NIR images. The surgical procedure was recorded, technical...
Objectives: This study evaluates the anatomical feasibility of an endoscopic transnasal approach for deep lateral orbital decompression using cadaver models. Design: Cadaver study. Participants: Four fresh frozen heads (eight-sides) were used. Main Outcome Measures: Measurements sphenoid trigone before and after bone removal assessed CT scans. Key outcome measures included width, height, depth, volume trigone. Results: The achieved a 53.9% reduction in volume, with significant decreases...
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease frequently requiring surgical intervention and the long-term use of topical corticosteroids to control patient symptoms. However, may delay postoperative recovery following sinus surgery by disrupting tissue inflammation, key mediator early wound healing. This study therefore seeks assess impact on sinonasal epithelial healing local injury. Methods Primary human cells (HNECs) were collected from...
EphrinA1-EphA-receptor signaling is protective during myocardial infarction (MI). The EphA2-receptor (EphA2-R) potentially mediates cardiomyocyte survival. To determine the role of EphA2-R in acute non-reperfused injury vivo, infarct size, inflammatory cell density, NF-κB, p-AKT/Akt, and MMP-2 protein levels, changes ephrinA1/EphA2-R gene expression profile were assessed 4 days post-MI B6129 wild-type (WT) EphA2-R-mutant (EphA2-R-M) mice lacking a functional EphA2-R. Fibrosis, capillary...
Dysfunctional vascular growth is a major contributor to cardiovascular disease, the leading cause of morbidity and mortality worldwide. Growth factor-induced activation smooth muscle cells (VSMCs) results in phenotypic switch from quiescent, contractile state proliferative foundational vessel pathology. Transforming factor-β (TGF-β) multifunctional signaling protein capable stimulation via Smad signaling. Although well characterized many tissues, its role VSM disorders remains controversial....
Immunoglobulin G4-related disease (IgG4-RD) is a recently described fibroinflammatory condition with characteristic histology. While IgG4-RD can affect great variety of anatomical sites, it has been seldom in the temporal bone.Herein, case occurring bone 35-year-old woman reported.This proved uniquely challenging diagnosis due to slightly atypical histology falling outside "highly suggestive" criteria.We suggest that remains reach despite increased awareness condition. We further...
BACKGROUND AND OBJECTIVES: Traditional and well-established transcranial approaches to the spheno-orbital region middle cranial fossa guarantee optimal intracranial exposure, additional orbital zygomatic osteotomies provide further control over extracranial components be resected; however, these techniques come at cost of morbidity. The introduction minimally invasive endoscopic conceptualization so-called “multiportal” paradigm might an alternative route. This preliminary study investigates...
There is limited evidence supporting the usage of prophylactic antibiotics in setting nasal packing for epistaxis. It unclear what current antiobiotic patterns are by otolaryngologists.Characterize antibiotic prescribing practices employed otolaryngologists management epistaxis patients treated with as well underlying rationale. Explore impact experience, geography, and academic affiliation on treatment decisions.An anonymous survey requiring was distributed to all physician members American...