A5051483675- Advanced Biosensing Techniques and Applications
- Photonic and Optical Devices
- Analytical Chemistry and Sensors
- Biosensors and Analytical Detection
- Advanced Fiber Optic Sensors
- Dielectric materials and actuators
- Advanced Fluorescence Microscopy Techniques
- Advanced biosensing and bioanalysis techniques
- Advanced Sensor and Energy Harvesting Materials
- Semiconductor Lasers and Optical Devices
- Conducting polymers and applications
- Force Microscopy Techniques and Applications
- Nanofabrication and Lithography Techniques
- Neural Networks and Reservoir Computing
- Greenhouse Technology and Climate Control
- Mycotoxins in Agriculture and Food
- Indoor Air Quality and Microbial Exposure
- Viral Infectious Diseases and Gene Expression in Insects
- Advanced MEMS and NEMS Technologies
- Light effects on plants
- Microfluidic and Bio-sensing Technologies
- Innovations in Aquaponics and Hydroponics Systems
- Mechanical and Optical Resonators
- Advanced Fiber Laser Technologies
- Gas Sensing Nanomaterials and Sensors
National Centre of Scientific Research "Demokritos"
2011-2023
A complete Mach-Zehnder interferometer monolithically integrated on silicon is presented and employed as a refractive index bio-chemical sensor. The device consists of broad-band light sources optically coupled to photodetectors through monomodal waveguides forming arrays interferometers, all components being mainstream technology. photonically engineered in way that the phase difference travelling sensing reference arms approximately wavelength independent. Consequently, upon effective...
Broad-band Mach-Zehnder interferometry is analytically described and experimentally demonstrated as an analytical tool capable of high accuracy refractive index measurements over a wide spectral range. Suitable photonic engineering the interferometer sensing reference waveguides result in sinusoidal TE TM spectra with substantially different eigen-frequencies. This allows for instantaneous deconvolution multiplexed polarizations enables large shifts noise reduction through filtering Fourier...
Abstract Protein detection and characterization based on Broad-band Mach-Zehnder Interferometry is analytically outlined demonstrated through a monolithic silicon microphotonic transducer. Arrays of light emitting diodes monomodal nitride waveguides forming interferometers were integrated chip. enters the exits sinusoidally modulated with two distinct spectral frequencies characteristic polarizations. Deconvolution in Fourier transform domain makes possible separation polarizations...
Despite the tremendous advances in micro- and nanoelectronics fast-pacing photonic circuit designs, seamless monolithic integration of electronic components on single chips still remains elusive. In this work, a radically designed silicon-based chip that monolithically integrates 37 mm2 footprint 10 interferometric optical sensors along with their respective sources, spectral analyzers, photodetector arrays is presented. The fabricated mainstream CMOS-compatible fabrication techniques...
Microgreens have gained attention for their exceptional culinary characteristics and high nutritional value. The present study focused on a novel approach investigating the easy extraction of plant samples utilization immersible silicon photonic sensors to determine, spot, nutrient content microgreens optimum time harvest. For first time, it was examined how these can capture time-shifting spectra caused by molecules’ dynamic adhesion onto sensor surface. experiment involved four types...
In this work, interferometric silicon chips with monolithically-integrated light-emitting devices coupled to co-integrated monomodal waveguides shaped as Young interferometers through mainstream technology, are presented. Although the light sources broad-band emitters, interferometry is possible filtering. Chips arrays of ten multiplexed have been employed for label-free determination pesticides in drinking water currently achieving detection limits ng/ml range.
An interferometric detection principle, capable of label-free biomolecules through the employment broadband light and integrated optics, is presented analyzed. Broadband Young interferometry (BB-YI) demonstrated to outperform standard monochromatic interferometers emergence two distinct packets interference fringes, one for TE TM polarization, on imaging array resulting in instantaneous independent measurement phase signal both polarizations over a wide range wavelengths. This dual...
A methodology for the prediction of chemocapacitor response due to sorption analyte without need fabrication actual devices is introduced. The based on experimental measurement volume fraction through reflectance measurements and electromagnetic modeling InterDigitated Electrode (IDE) capacitor. capacitance device are coupled use Clausius-Mossotti equation calculation dielectric constant sorbed polymeric film resulting in change analyte.
Miniaturized bioanalytical devices find wide applications ranging from blood tests to environmental monitoring. Such in the form of hand held personal laboratories can transform point-of-care monitoring provided miniaturization, multianalyte detection and sensitivity issues are successfully resolved. Optical biosensors is superior many respects other types sensing based on alternative signal transduction techniques, especially when both label free sought. The main drawback optical biosensing...
Despite the advances in optical biosensors, existing technological approaches still face two major challenges: inherent inability of most sensors to integrate source transducer chip, and need specifically design per application. In this work, development a radical optoelectronic platform is demonstrated based on monolithic optocoupler array fabricated by standard Si-technology suitable for multi-analyte detection. The has been designed biochemical sensing. all-silicon transducers, each its...
Optical biosensors have emerged in the past decade as most promising candidates for portable, highly-sensitive bioanalytical systems that can be employed in-situ measurements. In this work, a miniaturized optoelectronic system rapid, quantitative, label-free detection of harmful species food is presented. The proposed has four distinctive features render to powerful tool next generation Point-of-Need applications, namely it accommodates light sources and ten interferometric on single silicon...
The increasing demand of enhanced sensitivity in the detection various biochemical analytes paves way for development a new generation biosensors. Label free multianalyte immunosensing methods utilizing photonic probing have proven to result better and reliability than other types biosensing methods. Here we described monolithic silicon optoelectronic transducer capable label-free determinations. includes ten Mach-Zehnder interferometers each which is coupled its own broad band light...
An optical method is presented for in the situ monitoring of biomolecular films via reflection microscopy on patterned substrates. The based measuring coefficient a composite consisting substrate, layer, thin film to be monitored and cover medium. layer so that an array squares surrounded by bare substrate. reflectance difference between substrate observable, whose fractional changes reveal thickness through simple analytical expression. periodic image recorded digital microscope, Fourier...
A method is presented for label-free detection of protein-protein binding in real time.It based on the protein induced contrast modulation microscope image an oxidized and patterned silicon substrate.Interferometric effects make reflection coefficient solution-protein-oxide-silicon stack a function oxide-protein combined thickness.As consequence, pattern changes during experiment magnitude change measure progress biomolecular reaction.A model bioanalytical assay demonstrates potential method.