A5100461973- Domain Adaptation and Few-Shot Learning
- Nanoplatforms for cancer theranostics
- Hepatocellular Carcinoma Treatment and Prognosis
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Machine Learning and ELM
- Advanced biosensing and bioanalysis techniques
- Multimodal Machine Learning Applications
- Image Retrieval and Classification Techniques
- Optical measurement and interference techniques
- Radiomics and Machine Learning in Medical Imaging
- Parasitic infections in humans and animals
- Advanced Image and Video Retrieval Techniques
- Adaptive optics and wavefront sensing
- Remote-Sensing Image Classification
- Biosensors and Analytical Detection
- Microfluidic and Bio-sensing Technologies
- Infectious Aortic and Vascular Conditions
- Sirtuins and Resveratrol in Medicine
- Educational Robotics and Engineering
- Liver Disease and Transplantation
- Internet of Things and Social Network Interactions
- Advanced X-ray and CT Imaging
- Wireless Communication Networks Research
- Satellite Communication Systems
Zhejiang Cancer Hospital
2021-2025
Chinese Academy of Sciences
2017-2025
University of Liverpool
2025
Nanjing Medical University
2023
Ningxia University
2022-2023
Zhejiang Chinese Medical University
2022-2023
University of Chinese Academy of Sciences
2018-2022
Cancer Hospital of Chinese Academy of Medical Sciences
2022
Tongji University
2020-2022
Rensselaer Polytechnic Institute
2021
More recently, NCAPG2 has emerged as an intrinsically essential participant of the condensin II complex involved in process chromosome cohesion and stabilization mitosis, its position particular tumours is now being highlighted. Simultaneously, genetic properties hint that it might have enormous potential to interpret malignant progression tumors a broader perspective, is, pan-cancer. Yet, at present, this recognition remains merely superficial there lack more detailed studies explore...
Silica aerogel, a kind of nanoporous material, is regarded as desired drug carrier for its low toxicity, high specific surface area, and excellent biocompatibility. Using silica aerogel in may be an appropriate method to improve the performance pure resveratrol. In this study, resveratrol-loaded (RSA) delivery system was prepared by sol-gel method. Before gelling, resveratrol added into hydrolyzed tetraethyl orthosilicate (TEOS) ethanol solution then dispersed stir ultrasound. The results...
Circulating tumor cells (CTCs) can be the seeds of metastasis and are closely linked to cancer-related death. Fast effective detection CTCs is important for early diagnosis cancer evaluation micrometastasis. However, extreme rarity heterogeneity in peripheral blood make sensitive a big challenge. In this paper, TiO2-based surface-enhanced Raman scattering (SERS) bioprobe reported first time with outstanding ultrasensitive specificity, excellent stability signal, good biocompatibility CTCs....
The efficiency of immunotherapy for triple-negative breast cancer (TNBC) is relatively low due to the difficulty in accurately detecting immune checkpoints. detection TNBC-related programmed cell death ligand-1 (PD-L1) expression important guide and improve treatment efficiency. Surface-enhanced Raman spectroscopy (SERS) magnetic resonance (MR) imaging exhibit great potential early TNBC diagnosis. SERS, an optical mode, has advantages high sensitivity, good spatial resolution, "fingerprint"...
Resveratrol (RSV) is a natural flavonoid polyphenol compound extracted from the plants which shows various biological activities. However, clinical application of RSV limited by its poor aqueous solubility, rapid metabolism and bioavailability. In this study, resveratrol-loaded solid lipid nanoparticles (RSV- SLNs) was design as nano-antioxidant against physical fatigue. The resultant RSV-SLNs were characterized photon correlation spectroscopy (PCS), transmission electron micrographs (TEM),...
Purpose To accurately assess disease progression after Stereotactic Ablative Radiotherapy (SABR) of early-stage Non-Small Cell Lung Cancer (NSCLC), a combined predictive model based on pre-treatment CT radiomics features and clinical factors was established. Methods This study retrospectively analyzed the data 96 patients with NSCLC treated SABR. Clinical included general information (e.g. gender, age, KPS, Charlson score, lung function, smoking status), lesion status diameter, location,...
Fe 3 O 4 –Au complex SERS bioprobe could effectively capture the TNBC and endow tumor cells with remarkable signals. Detection sensitivity specificity of CTCs be intelligently switched according to identification purposes.
Computer-generated hologram (CGH) has been widely used as a wavefront compensator in symmetric aspheric metrology. As diffractive element, it generates different diffraction orders, but only the 1st-order is to test surface. The light from spurious orders (SDO) will produce many high-frequency fringes interferogram and reduce measurement accuracy. In this paper, we regard CGH null system an imaging develop aberration model Seidel formalism analyze SDO. This advantage address difference...
We present and analyze a new measurement method of freeform surfaces with deformable mirror (DM), which functions as wavefront compensator. discuss the maximum slope compensation DM in first-order approximation derive how to calculate ideal form. A constrained optimization procedure is conducted ensure actual form fits closely possible. To demonstrate feasibility understand measurable range our method, we evaluate single Zernike term, first 36 random terms, 230 terms. tolerance analysis...
Currently, clinically available drug-loaded embolic microspheres have some shortcomings, such as being invisible with standard medical imaging modalities and only able to carry positively charged drugs. The visualization of is very important for real-time monitoring position improve the therapeutic effect. Meanwhile, can enable postoperative reexamination, which helpful evaluating embolization area guiding subsequent treatment. In addition, capable loading different drugs increase choice...
DC Beads and CalliSpheres are commonly used microspheres in clinical transcatheter arterial chemoembolization, but these cannot be visualized by themselves. Therefore, our previous study, we developed multimodal imaging nano-assembled (NAMs), which under CT/MR the location of embolic can determined during postoperative review, facilitating evaluation areas guiding subsequent treatment. Moreover, NAMs carried with positively negatively charged drugs, increasing choice drugs. Systematic...
This study aimed to investigate the idarubicin loading method, compatible stability with contrast agent, release profiles, and morphological properties of 50–150, 100–300, 300–500 μm CalliSpheres®. The amounts added, medium, condition, drug concentration were investigated as factors influencing efficiency. rate was negatively correlated amount added diameter CalliSpheres® positively concentration. Compared in purified water incubation at room temperature, 5% glucose, heating, ultrasound...
A transmission dynamics model with the logistic growth of cystic echinococcus in sheep was formulated and analyzed. The basic reproduction number derived results showed that global dynamical behaviors were determined by its value. disease-free equilibrium is globally asymptotically stable when value less than one; otherwise, there exists a unique endemic it stable. Sensitivity analysis uncertainty also performed to screen important factors influence spread echinococcosis. Contour plots...
In adversarial environment such as intrusion detection and spam filtering, the adversary-intruder or advertiser may attempt to produce contaminate training instance manipulate learning of classifier. order keep good classification performance, many robuster methods have been proposed deal with attack. Support Vector Machines(SVMs) is a kind successful approach in tasks investigation robust SVMs very popular. However, real application, data including stain coming dynamically. Batch which...
Domain adaptation has recently attracted attention for visual recognition. It assumes that source and target domain data are drawn from the same feature space but different margin distributions its motivation is to utilize instances assist in training a robust classifier tasks. Previous studies always focus on reducing distribution mismatch across domains. However, many real‐world applications, there also exist problems of sample selection bias among domain; this would reduce generalization...
Introduction: In recent years, the development of drug-eluting embolization beads that can be imaged has become a hot research topic in regard to meeting clinical needs. our previous study, we successfully developed nano-assembled microspheres (NAMs) for multimodal imaging purposes. NAMs not only visualized under CT/MR/Raman but also load clinically required doses doxorubicin. It is important systematically compare pharmacokinetics with those commercially available DC Beads and CalliSpheres...