A5074179192- Hearing Loss and Rehabilitation
- Noise Effects and Management
- Hearing, Cochlea, Tinnitus, Genetics
- Speech and Audio Processing
- Neuroscience and Music Perception
- Tactile and Sensory Interactions
- Voice and Speech Disorders
- Acoustic Wave Phenomena Research
- Ear Surgery and Otitis Media
- Facial Nerve Paralysis Treatment and Research
- Ear and Head Tumors
- NF-κB Signaling Pathways
- Peroxisome Proliferator-Activated Receptors
Fudan University
2016-2024
Eye & ENT Hospital of Fudan University
2020-2021
Shanghai Clinical Research Center
2021
House Clinic
2018
Soochow University
2016-2018
First Affiliated Hospital of Soochow University
2016-2018
National Health and Family Planning Commission
2018
Weatherford College
2016
University of California, Los Angeles
2016
Howard Hughes Medical Institute
2016
Due to limited spectral resolution, cochlear implants (CIs) do not convey pitch information very well. Pitch cues are important for perception of music and tonal language; it is possible that training may improve performance in both listening tasks. In this study, we investigated outcomes terms music, lexical tones, sentences 22 young (4.8 9.3 years old), prelingually deaf Mandarin-speaking CI users. Music was measured using a melodic contour identification (MCI) task. Speech tones presented...
Patients with single-sided deafness (SSD) often experience poor sound localization, reduced speech understanding in noise, quality of life, and tinnitus. The present study aims to evaluate effects tinnitus duration on localization recognition noise by SSD subjects. Sound were measured 26 10 normal-hearing (NH) Speech was always presented directly front the listener. Noise deaf ear, listener, or better hearing ear. Tinnitus severity using visual analog scale Handicap Inventory. Relative NH...
Objective . The aim of this study was to investigate the benefits residual hair cell function for speech and music perception in bimodal pediatric Mandarin-speaking cochlear implant (CI) listeners. Design Speech performance measured 35 CI users unilateral (CI-only) listening. Mandarin vowels, consonants, lexical tones, sentences quiet. Music melodic contour identification (MCI). Results Combined electric acoustic hearing significantly improved MCI tone recognition performance, relative...
Due to poor perception of fundamental frequency (F0) cues that are important for lexical tone and talker segregation, pediatric Chinese cochlear implant (CI) users may be especially susceptible informational masking. Here, speech recognition thresholds (SRTs) were measured in steady noise or competing Mandarin-speaking CI normal-hearing (NH) children. children more masking unable use F0 segregate talkers. SRTs significantly correlated with chronological age NH duration deafness children,...
While fundamental frequency (F0) cues are important to both lexical tone perception and multitalker segregation, F0 poorly perceived by cochlear implant (CI) users. Adding low-frequency acoustic hearing via a aid in the contralateral ear may improve CI users' perception. For English-speaking users, has been shown of target speech noise competing talkers. tonal languages such as Mandarin Chinese, information is lexically meaningful. Given from multiple talkers tones, be especially beneficial...
The aim of this study was to replicate previous English-language musician advantage studies in Mandarin-speaking musicians and nonmusicians. Segregation competing speech, melodic pitch perception, spectro-temporal pattern perception were measured normal-hearing native Speech recognition thresholds the presence two-talker masker speech. sex either same as or different from target; target speech co-located spatially separated. Melodic tested using a contour identification task....
<b><i>Objective:</i></b> The objective of this study was to examine whether cochlear implantation using the round window (RW) route versus cochleostomy achieves comparable electrode impedance and hearing results. <b><i>Methods:</i></b> This retrospective analysis included 40 patients receiving a implant (REZ-1): 20 RW approach remaining cochleostomy. Electrode tone, vowel, consonant, disyllable sentence perception were measured during after...
The aims of this article are: 1) to re-evaluate the accuracy multiple planar reconstruction computed tomography (MPR-CT) imaging on stapes-prosthesis parameters, and 2) clarify possible relationships between prosthesis intravestibular depth postoperative hearing outcomes.Seventy patients (46 women 24 men; 32 right 38 left sides) with mean age 40 years (range, 19-62 yr) clinical otosclerosis.All underwent stapedotomy were implanted same type titanium piston by surgeon.Postoperative MPR-CTs...
Cholesteatoma is characterized by both the overgrowth of hyperkeratinized squamous epithelium and bone erosion. However, exact mechanism underlying hyperproliferative ability cholesteatoma remains unknown. In this study, we investigated PPAR β/δ expression in human surgical specimens analyzed its functional role as a regulator epithelial keratinocyte hyperproliferation. We found that was significantly upregulated ligand-activated markedly promoted proliferation keratinocytes. Furthermore,...
Children with normal hearing (CNH) have greater difficulty segregating competing speech than do adults (ANH). cochlear implants (CCI) CNH. In the present study, reception thresholds (SRTs) in were measured Chinese Mandarin-speaking ANH, CNH, and CCIs. Target sentences produced by a male talker. Maskers time-forward or -reversed native (different from target) female non-native English-speaking male. The SRTs lowest (best) for ANH group, followed CNH CCI groups. masking release (MR) was...
To investigate the effects of spatial separation and noise type on sentence recognition by unilateral Mandarin-speaking cochlear implant (CI) users normal-hearing (NH) listeners.Twenty-two CI six NH listeners participated in this study. Speech reception thresholds were measured for three types (steady state noise, speech babble, music). Sentences from Mandarin Perception test presented directly front listener (0°). Noise was one five speaker locations: -90°, -45°, 0°, +45°, +90°.Overall,...
Objective To assess any differences in spatial listening ability of cochlear implant recipients when using both or only one two bilateral implants (BCIs) for stimuli originating from behind the subject.Design Twelve loudspeakers were placed rear horizontal plane subjects to test sound localisation performance BCI users and normal-hearing listeners (NHLs) with without interfering noise. Stimuli presented via simultaneously during speech recognition test. In tone test, another anechoic chamber...