- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Cancer Treatment and Pharmacology
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Surgical Treatments
- Intraperitoneal and Appendiceal Malignancies
- Birth, Development, and Health
- Appendicitis Diagnosis and Management
- Radiomics and Machine Learning in Medical Imaging
- Hernia repair and management
- Pregnancy and preeclampsia studies
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- HER2/EGFR in Cancer Research
- Pancreatic and Hepatic Oncology Research
- Enhanced Recovery After Surgery
- Psoriasis: Treatment and Pathogenesis
- Bone health and osteoporosis research
- Education Practices and Challenges
- Autoimmune Bullous Skin Diseases
- Silymarin and Mushroom Poisoning
- Inflammation biomarkers and pathways
- Congenital Heart Disease Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
University of Health Science
2025
University of Health Sciences
2020-2022
University of Health Sciences Antigua
2020-2022
Haseki Eğitim ve Araştırma Hastanesi
2022
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2018-2021
Sağlık Bilimleri Üniversitesi
2019-2021
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2013
Istanbul Medeniyet University
2012
Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity received most focus as possible etiology. Our aim in this prospective clinical study was to investigate association between cytokines, interleukin IL-17, IL-22, IL-23 IGM.The current conducted 26 women with histopathologically diagnosed IGM, 15 control of reproductive age having no history. Blood samples were...
<title>Abstract</title> Background Pre-eclampsia continues to be a significant global health burden with complex pathophysiology, necessitating investigation of novel biomarkers improve understanding, diagnosis and management this pregnancy-specific disorder.To investigate the differential expression Calcium Release-Activated Channel Protein 1 (ORAI1), Fibroblast Growth Factor 23 (FGF23), Placental 13 (PP13), Palladin, Supervillin in both maternal umbilical cord blood as potential for...
ÖZ
SENKRON KOLOREKTAL TÜMÖRLER: KLİNİK DENEYİMLERİMİZ
 GİRİŞ VE AMAÇ:
 Senkron kolorektal kanserler; tüm kanserlerin (KRK) %1,1-8,1’ini oluşturur ve preoperatif tespit edilmeleri, cerrahi tedaviyi prognozu doğrudan etkilemektedir. Bu nedenle çalışmamızda kliniğimizde senkron kolon tümörü tanısı koyduğumuz olguların klinikopatolojik özellikleri, tedavi sağkalım sonuçları değerlendirilmiştir.
 
 YÖNTEM GEREÇLER:
 Ocak 2009- Aralık 2018 tarihleri arasında, almış 17 olgunun...
Background: Uncarboxylated osteocalcin (uOCN) synthesized by osteoblasts was shown to increase insulin secretion and peripheral sensitivity in pancreatic islets. The present study evaluated the uOCN levels its association with metabolic parameters non-diabetic patients syndrome (MetS) test our hypothesis that may be lower MetS, which is characterized resistance. Methods: included 30 MetS aged 18 years above (13 male, 17 female, mean age 39.00 ± 5.09 years) healthy controls (15 15 36.23 6.71...
Objective: To determine the relationship between resected specimen length and tumor location, number of LN harvested (LNh), positive ratio (LNR) in colon cancer.
Postoperative ischemia could affect the evaluation of breast cancer tissue for steroid hormone receptors and c-erbB2 levels until fixation using formalin. The misevaluation levels, which are important prognostic factors in treatment cancer, change options. aim this study was to investigate effects postoperative on a sample, particularly expression level.
Aim: The diagnosis of acute appendicitis is still challenging. Negative appendectomy rate reported as 20-30%. Therefore, various scoring systems have been developed to prevent unnecessary appendectomies. aim our study analyze the diagnostic value different in appendicitis. Material and Method: conducted with 200 consecutive patients who were operated After admission deciding operation via experienced general surgeon, probability was calculated using 6 systems: Alvarado, Eskelinen, Ohmann,...
Abstract Purpose: We aimed to determine the predictive values of fetal pancreas size and maternal serum biomarkers glycated albumin (GA) insulin-regulated aminopeptidase (IRAP) for gestational diabetes mellitus (GDM). Material methods: In this prospective observational study including 109 pregnant women, GA IRAP were measured at age 20-22 weeks later 24-28 weeks, in 19 participants them, GDM was confirmed with 75-g oral glucose tolerance test (OGTT) all again. Results: The median sizes...
Amaç: Oksaliplatin bazlı kemoterapinin karaciğer metastazlı kolon kanserli hastalarda kullanımı hasarına (sinüsoidal obstruktif sendrom (SOS)) neden olarak; metastaz rezeksiyonu sonrasında mortalite ve morbiditeyi arttırır. Bu çalışmamızda; sildenafilin kolorektal kanserlerin metastazları için oksaliplatin kemoterapi sonucunda gelişen hasarı, (SOS) üzerindeki koruyucu etkisini değerlendirmeyi amaçladık.Yöntemler: Deneysel bir hayvan çalışması yürütüldü toplam 42 rat rastgele Sham,...
Introduction: Our aim is to determine the value of a pre-operative Computed Tomography (CT) scan for assessment lymph node status in patients diagnosed with colon cancer by comparing between radiological N-stage and histopathological N-stage.Methods: After approving local ethics committee, an experinced radiologist reviewed all preoperative CT scans retrospectively, January 2014 December 2018.The were examined any signs regional lymphatic spread which was defined as nodes exceeding 1 cm,...
Mallory-Weiss sendromu mide-özefagus bileşkesindeki mukozada yırtıktan kanamaya kadar giden bir durumu ifade eder. Antikoagülan tedavi altındaki protez mitral kapaklı hastalarda kanama hayatı tehdit eden majör komplikasyondur. Burada; warfarin sodyum tedavisi hastada ile ilişkili üst gastrointestinal sistem kanaması sunulmuştur.
ÖZET GİRİŞ ve AMAÇ: Mide kanseri tüm dünyada her yıl yaklaşık yarım milyon hastanın ölümüne neden olmaktadır.Dinamik abdominal BT preoperatif tanı mide kanserlerinin evrelemesinde yaygın olarak kullanılmaktadır.Burada en önemli nokta evrelemenin doğru yapılarak, hastaların neoadjuvan kemoterapi gibi uygun tedavi seçeneklerine kavuşabilmesidir.Dinamik BT'nin rolünü daha da netleştirmek için; bulgularını postoperatif histopatolojik bulgular eşliğinde
NF1 hastalarının %10-25'inde gastrointestinal tutulum saptansada, asemptomatik klinik seyirleri nedeniyle genellikle gözardı edilirler.Hastanemize anemi nedeni araştırılmak üzere 33 yaşında erkek hasta sevk edildi.Hastanın ilk muayenesinde; bulguları; Lisch nodülleri, Cafe u lait lekeleri ve nörofibromlar tespit edildi.Kolonoskopide; transvers kolon proksimalinde 5x3x2 cm boyutlarında hemorajik polip edildi laparoskopik sağ hemikolektomi
Aim: The differential diagnosis of benign and malignant diseases the thyroid is important in borderline malignancies that have not been diagnosed with biopsy. This study aimed to determine endocan molecule levels patients cancer, nodular goiter thyroiditis. Thus, it was availability diseases. Material Method: conducted between March 1, 2018 August 2018. During this period, who were scheduled for surgery due disease wanted participate voluntarily included study. A prospective, cross-sectional...
Amaç: Kolon kanserinin küratif cerrahisinde ≥12 lenf nodunun diseke edilmesi önerilmektedir.Bu çalışmada yetersiz nodu diseksiyonuna etki eden klinikopatolojik faktörleri