Halil Zeki Tonbul

ORCID: 0000-0003-0761-3697
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About
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Research Areas
  • Dialysis and Renal Disease Management
  • Parathyroid Disorders and Treatments
  • Acute Kidney Injury Research
  • COVID-19 Clinical Research Studies
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Disease and Adiposity
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • COVID-19 and healthcare impacts
  • Muscle and Compartmental Disorders
  • Long-Term Effects of COVID-19
  • Renal Transplantation Outcomes and Treatments
  • Central Venous Catheters and Hemodialysis
  • Hemoglobinopathies and Related Disorders
  • Erythropoietin and Anemia Treatment
  • Complement system in diseases
  • Renal and Vascular Pathologies
  • Inflammatory Biomarkers in Disease Prognosis
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Dietary Effects on Health
  • Potassium and Related Disorders
  • Pregnancy and preeclampsia studies
  • Lysosomal Storage Disorders Research
  • Chronic Kidney Disease and Diabetes
  • Organ Donation and Transplantation
  • Ottoman and Turkish Studies

Necmettin Erbakan University
2016-2025

Selçuk University
1999-2012

Pediatric Nephrology of Alabama
1998-2012

Istanbul University
2001

Atatürk University
1998-2000

Abstract Neutrophil‐to‐lymphocyte ratio ( NLR ) was introduced as a potential marker to determine inflammation in end‐stage renal disease ESRD patients. Recently, platelet‐to‐lymphocyte PLR and were found positively correlated with inflammatory markers including tumor necrosis factor‐α TNF ‐α) interleukin IL )‐6 cardiac noncardiac Data regarding its association are lacking hemodialysis HD peritoneal dialysis PD Hence, we aimed the relationship between , This cross‐sectional study involving...

10.1111/hdi.12040 article EN Hemodialysis International 2013-03-24

Abstract Background Chronic kidney disease (CKD) and immunosuppression, such as in renal transplantation (RT), stand one of the established potential risk factors for severe coronavirus 2019 (COVID-19). Case morbidity mortality rates any type infection have always been much higher CKD, haemodialysis (HD) RT patients than general population. A large study comparing COVID-19 outcome moderate to advanced CKD (Stages 3–5), HD with a control group is still lacking. Methods We conducted...

10.1093/ndt/gfaa271 article EN cc-by-nc Nephrology Dialysis Transplantation 2020-10-07

Patients with end-stage renal disease (ESRD) have elevated serum levels of inflammatory mediators including C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and interleukin (IL)-6. Systemic inflammation was found to be correlated coronary artery (CAD) in this population. Neutrophil-to-lymphocyte ratio (NLR) introduced as a potential marker determine cardiac non-cardiac disorders. Data regarding NLR its association are lacking. We aimed the relationship between ESRD patients.This...

10.3109/0886022x.2011.641514 article EN Renal Failure 2011-12-16

Background. Longer dialysis sessions may improve outcome in haemodialysis (HD) patients. We compared the clinical and laboratory outcomes of 8- 4-h thrice-weekly HD.

10.1093/ndt/gfq724 article EN Nephrology Dialysis Transplantation 2010-12-09

Abstract Background Maintenance hemodialysis (MHD) patients are at increased risk for coronavirus disease 2019 (COVID-19). The aim of this study was to describe clinical, laboratory, and radiologic characteristics determinants mortality in a large group MHD hospitalized COVID-19. Methods This multicenter, retrospective, observational collected data from 47 nephrology clinics Turkey. Baseline laboratory radiological characteristics, COVID-19 treatments during hospitalization, need intensive...

10.1186/s12882-021-02233-0 article EN cc-by BMC Nephrology 2021-01-14

Abstract Background We aimed to present the demographic characteristics, clinical presentation, and outcomes of our multicenter cohort adult KTx recipients with COVID-19. Methods conducted a multicenter, retrospective study using data patients hospitalized for COVID-19 collected from 34 centers in Turkey. Demographic findings, laboratory parameters (hemogram, CRP, AST, ALT, LDH, ferritin) at admission follow-up, treatment strategies were reviewed. Predictors poor analyzed. The primary...

10.1186/s12882-021-02299-w article EN cc-by BMC Nephrology 2021-03-19

Summary Background and objectives Malnutrition, inflammation, atherosclerosis/calcification (MIAC) endothelial dysfunction are the most commonly encountered risk factors in pathogenesis of cardiovascular disease ESRD patients. Epicardial adipose tissue (EAT) is true visceral fat depot heart. The relationship between CAD EAT was shown patients with high coronary artery disease. In this study, we aimed to investigate MIAC syndrome Design, setting, participants, & measurements Eighty 27...

10.2215/cjn.00890111 article EN Clinical Journal of the American Society of Nephrology 2011-07-15

Chronic inflammation was found to be correlated with coronary (CAC) and thoracic peri-aortic calcification (TAC) in end-stage renal disease (ESRD) patients. Neutrophil-to-lymphocyte ratio (NLR) introduced as a potential marker determine cardiac noncardiac disorders. Data regarding NLR its association TAC CAC are lacking. We aimed the relationship between vascular ESRD This cross-sectional study involving 56 patients (22 females, 34 males; mean age, 49.9 ± 14.2 years) receiving peritoneal...

10.1111/hdi.12065 article EN Hemodialysis International 2013-07-03

Sexual dysfunction, including erectile is common in patients with uraemia. Despite successful treatment of male sexual dysfunction sildenafil non-uraemic population, its efficacy dialysis unknown.In this study, 35 HD (mean age 48+/-12 years) and 15 CAPD 44+/-12 were included. In the baseline period, haemoglobin, serum urea, albumin, Kt/V, several hormonal parameters, Beck depression scale, penile Doppler blood flow, (peak systolic velocity after intracavernous papaverine administration)...

10.1093/ndt/16.9.1818 article EN Nephrology Dialysis Transplantation 2001-09-01

<b><i>Background/Aims: </i></b>Fabry disease is a treatable cause of chronic kidney (CKD) characterized by genetic deficiency α-galactosidase A. European Renal Best Practice (ERBP) recommends screening for Fabry in CKD patients. However, this based on expert opinion and there are no reports the prevalence stage 1-5 CKD. Hence, we investigated patients not receiving renal replacement therapy. <b><i>Methods: </i></b>This prospective study...

10.1159/000452605 article EN cc-by-nc-nd Kidney & Blood Pressure Research 2016-01-01

Despite some improvements in dialysis therapies, depression still remains an important problem chronic hemodialysis (HD) patients. In this study, we aimed to investigate the association of and its treatment with quality life (QOL) HD patients.97 patients (52 male, 45 female, mean age 55 +/- 16 years) were enrolled. All had been dialyzed for more than 6 months. order evaluate QOL patients, a short form Medical Outcomes Study (SF-36) was used. Depression assessed by using Beck Inventory (BDI)....

10.5414/cnp65113 article EN Clinical Nephrology 2006-02-01
Özkan Güngör Berfu Korucu EBRU GÖK OĞUZ Necmi Eren Zeynep Ural and 95 more Hamad Dheir Erhan Tatar Ayça İnci İsmail Koçyiğit Zeki Aydın Özkan Ulutaş Ekrem Kara Orçun Altunören Zülfükar Yılmaz Mustafa Sevinç Can Sevinç Atalay Surardamar Mahmud İslam Cüneyt Akgöl Halil Zeki Tonbul Tuba Elif Özler İbrahim Güney Şimal Köksal Cevher Cihan Uysal Fatma Betül Güzel Rüya Mutluay Zafer Ercan Semahat Karahisar Şirali Erdem Çankaya Engin Onan Ferhan Candan Eray Eroğlu Neslihan Tezcan Mehmet Emrah Polat Can Hüzmeli Sultan Özkurt Tulin Aksgün Pınar Alp Rüya Özelsancak Gurkan YURTERİ Mehmet Tanrısev Abdulselam İlter Beyhan Güvercin Mehmet Emin Demir Özdem Kavraz Tomar Alper Azak Faruk Turğut Mehmet Tuncay Hakan Akdam Tamer Selen Fatih Yılmaz Ramazan Danış Şahin Eyüpoğlu Gizem Kumru Simge Bardak Demir Selma Alagöz Sami Uzun orhan özdemir Zelal Adıbelli Mehmet Emrah Polat Ramazan Ulu Ahmet Murt Mürşide Esra Dölarslan Z. Bal Yavuz Ayar Nazife Nur Özer Şensoy Mehmet Sezen TuncayŞahutoğlu Ali Veysel Kara Ercan Türkmen Hasan KAYABAŞI Numan Görgülü Ender Hür Sibel Yücel Koçak Zehra Eren Garip Şahin Umut Sabri Kasapoğlu Zeynep Bıyık Sümeyra Koyuncu Mehtap Aydın Tolga Yıldırım Gülşah Şaşak Kuzgun Sedat Üstündağ Abdulkadir Çelik Esra Akçalı Ozlem Usalan BülentKaya Mehmet Rıza Altıparmak Murat Tuğçu Refik Olmaz Edip Erkuş Zeki Soypaçacı Belma Gökçen Zorba Demet Yavuz Kenan Evren Öztop Melike Betül Öğütmen Özlem Harmankaya Dilek Güven Taymez Hakan Kaptanoğulları Kemal Mağden

Abstract Background The most common cause of end-stage kidney disease is diabetes mellitus (DM). commonly used renal replacement therapy in our country and many countries around the world hemodialysis (HD). Glycemia control important these populations. In this study, we aimed to screen for glycemic complications a large population diabetic HD patients country. Methods 16043 were screened 253 dialysis centers Turkey. 5038 included study. At participating centers, patients' history,...

10.1093/ckj/sfaf120 article EN cc-by-nc Clinical Kidney Journal 2025-04-18

HELLP syndrome, a syndrome of hemolysis, elevated liver enzymes and low platelets may occur in pregnancy with pre-eclampsia/eclampsia, its significant complication is acute renal failure (ARF).The aim study was to determine frequency outcome complicated by ARF.Thirty-nine patients pregnancy-related ARF were treated between Jan 1, 1989 1999. In these patients, the most frequent causes (n = 14; 36%), postpartum hemorrhage 10; 26%), pre-eclampsia/eclampsia 6;15%) abruptio placenta 4;10%). Seven...

10.1081/jdi-100100875 article EN Renal Failure 2000-01-01

In this study, clinical features, developing complications, and results of thirty-six patients, which were followed up in our Obstetrics Gynecology Nephrology departments between 1997 2001, with the diagnosis HELLP syndrome searched retrospectively. The mean age cases 30.2 +/- 5.9 (17-46) years. was diagnosed on average 32.6 4.8th (23-41) week gestations. Seventy percent severe preeclampsia 30% mild preeclampsia. Eleven (30%) nullipara twenty-five (70%) multipara. arterial systolic blood...

10.1081/jdi-120022553 article EN Renal Failure 2003-01-01

In recent years, the incidence of acute renal failure (ARF) in pregnancy has decreased developed countries. This cause this decline been reported to be liberalized abortion laws and improved prenatal care. The aim study was determine if etiology ARE our population had undergone similar changes. Between January 1, 1980 1 1997 number patients with ARF 487. 74 (15%) these patients, associated pregnancy. frequency 17.4% between August 1985, 15.4% September 1985 November 1989, 13.5% December 1989...

10.3109/08860229809045140 article EN Renal Failure 1998-01-01

Background. Malnutrition, inflammation, and atherosclerosis (MIA syndrome) are common in end-stage renal disease (ESRD) patients. Each component of MIA syndrome is the predictor outcomes ESRD In this cross-sectional study, we aimed to compare both dialysis modalities for components. Material Methods. Thirty hemodialysis (HD) (mean age 44 ± 11 years, 14 male 16 female, mean time on dialysis: 31.0 19.0 months) 30 continuous ambulatory peritoneal (CAPD) patients (41 9 12 18 25.5 21.5 were...

10.1080/08860220600583625 article EN Renal Failure 2006-01-01

In this study of 26 patients, clinical features diagnosed as urinary tuberculosis in our nephrology and urology clinics between 1993 2002 were investigated retrospectively. Fifteen patients (52%) male, mean age was 43.5 (18–71). Twenty percent the asymptomatic. Frequency-dysuria (46%), flank pain (33%), macroscopic hematuria (12%) presenting symptoms. Physical examination not diagnostically helpful most patients. Hematuria and/or pyuria detected 80% Eleven had positive urine cultures...

10.1080/08860220500234857 article EN Renal Failure 2005-01-01

Introduction: Epicardial adipose tissue (EAT) is the true visceral fat depot of heart. The relationship between coronary artery disease and EAT was shown in end-stage renal (ESRD) patients. One established risk factor this population dyslipidemia. We aimed to determine atherogenic index plasma (AIP) ESRD Methods: This a cross-sectional study involving 76 patients receiving PD or HD for ≥6 months 42 healthy subjects. measured by using an electrocardiogram-gated 64-multidetector computed...

10.3109/0886022x.2013.823826 article EN Renal Failure 2013-08-07

BACKGROUND: Atherosclerosis, endothelial dysfunction, coronary artery calcification (CAC), and left ventricular hypertrophy are the most commonly encountered risk factors in pathogenesis of cardiovascular disease end-stage renal patients. Epicardial adipose tissue (EAT) is true visceral fat depot heart. The relationship between EAT has been shown healthy subjects patients with a high disease. In present study, we aimed to investigate CAC peritoneal dialysis (PD) Patients Methods: Forty-five...

10.1159/000335495 article EN Cardiorenal Medicine 2012-01-01

Atherosclerosis, coronary artery calcification, diabetes mellitus, inflammation, endothelial dysfunction, and left ventricular hypertrophy are the most commonly encountered risk factors in pathogenesis of cardiovascular disease end-stage renal (ESRD) patients. Epicardial adipose tissue (EAT) is true visceral fat depot heart. The relationship between (CAD) EAT was shown healthy subjects patients with high CAD. To date, there not enough data about diabetic nondiabetic ESRD Therefore, we aimed...

10.3109/0886022x.2011.599913 article EN Renal Failure 2011-07-20

Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period not been published extensively.We conducted a national, multicenter observational study that included adult maintenance HD recovered from confirmed A control group without COVID-19 was selected in same center. We investigated characteristics follow-up compare them with non-COVID-19 group.A total 1223 (635 group, 588 group) 47 centers were...

10.1016/j.ekir.2022.03.017 article EN cc-by-nc-nd Kidney International Reports 2022-03-25
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