A5087514334- Glioma Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Acute Ischemic Stroke Management
- Lanthanide and Transition Metal Complexes
- Medical Imaging Techniques and Applications
- Sarcoma Diagnosis and Treatment
- Multiple Sclerosis Research Studies
- Cancer, Hypoxia, and Metabolism
- Cerebrovascular and Carotid Artery Diseases
- Bone and Joint Diseases
- Peripheral Neuropathies and Disorders
- Cancer Research and Treatments
- Cerebrospinal fluid and hydrocephalus
- Ferroptosis and cancer prognosis
- Magnetism in coordination complexes
- Traumatic Brain Injury Research
- Polyomavirus and related diseases
- Spinal Dysraphism and Malformations
- MicroRNA in disease regulation
Tongji Hospital
2015-2025
Huazhong University of Science and Technology
2015-2025
Zero to Three
2016
// Rifeng Jiang 1, * , Jingjing Lingyun Zhao 1 Jiaxuan Zhang Shun Yihao Yao Shiqi Yang Shi Nanxi Shen Changliang Su Ju Wenzhen Zhu Department of Radiology, Tongji Hospital, Medical College, Huazhong University Science and Technology, Wuhan, China These authors have contributed equally to this work Correspondence to: Zhu, e-mail: zhuwenzhen@hotmail.com Keywords: diffusion kurtosis imaging, glioma, grading, cellular proliferation, Ki-67 Received: April 29, 2015 ...
Purpose To determine the utility of intravoxel incoherent motion (IVIM) imaging in grading gliomas and compare IVIM perfusion metrics with arterial spin labeling (ASL)‐derived cerebral blood flow (CBF). Materials Methods Fifty‐two patients pathologically confirmed underwent ASL at 3.0T. perfusion‐related diffusivity (D*), fraction (f), product f D*(f×D*), true (D), apparent diffusion coefficient (ADC) were obtained to distinguish glioma grades. The CBF derived from pseudocontinuous within...
This study aimed to assess the spatiotemporal evolution of oxygen extraction fraction (OEF) in ischemic stroke with a newly developed cluster analysis time (CAT) for combined quantitative susceptibility mapping and blood level-dependent model (QSM + qBOLD, QQ).One hundred fifteen patients different phases were retrospectively collected measurement OEF infarcted area defined on diffusion-weighted imaging (DWI). Clinical severity was assessed using National Institutes Health Stroke Scale...
Background: Paramagnetic rim lesions (PRLs) on susceptibility magnetic resonance sequences have been suggested as an imaging marker of disease progression in multiple sclerosis. This retrospective cross-sectional study aimed to investigate the impact PRLs cortical thickness and gray matter (GM) white (WM) contrast relapsing-remitting sclerosis (RRMS).
Background: The intratumoral heterogeneity of oxygen metabolism and angiogenesis are core hallmarks glioma, unveiling that genetic aberrations associated with magnetic resonance imaging (MRI) phenotypes may aid in the diagnosis treatment glioma. Objective: To explore predictability MRI-based extraction fraction (OEF) mapping using cluster analysis time evolution (CAT) for profiling glioma grading. Methods: Ninety-one patients histopathologically confirmed were examined CAT quantitative...
Gliomas are highly invasive brain tumors that evade accurate geographic assessment by conventional MRI due to microscopic invasion along white matter (WM) tracts. Advanced diffusion techniques needed assess occult WM involvement.
Objectives: To compare the efficacy of parameters from multiple diffusion magnetic resonance imaging (dMRI) for prediction isocitrate dehydrogenase 1 (IDH1) genotype and assessment cell proliferation in gliomas. Methods: Ninety-one patients with glioma underwent weighted (DWI), multi-b-value DWI, kurtosis (DKI)/neurite orientation dispersion density (NODDI) on 3.0T MRI. Each parameter was compared between IDH1-mutant IDH1 wild-type groups by Mann-Whitney U test lower-grade gliomas (LrGGs)...
Cuproptosis is implicated in regulating tricarboxylic acid cycle and associated with tumor therapeutic sensitivity, patient outcomes tumorigenesis. However, the classification prognostic effect of cuproptosis-associated genes (CAGs), relationship between cuproptosis microenvironment (TME) treatment lower-grade glioma (LrGG) remain enigmatic.The genetic transcriptional alterations, value related to were systematically analyzed. Subtypes score (Cuscore) constructed further confirmed by two...
The diffusion tensor image analysis along the perivascular space (DTI-ALPS) may have potential to reflect glymphatic dysfunction in patients with glioma. study aimed determine correlation of DTI-ALPS glioma grade and isocitrate dehydrogenase 1 (IDH1) genotype then compare ALPS index other metrics.In this study, 81 31 healthy controls underwent magnetic resonance imaging (MRI) examination. ALPS-index, fractional anisotropy (FA), mean diffusivity (MD), kurtosis (MK) were calculated....
Background Corticospinal tract (CST) injury has been shown to exert a major influence on functional recovery after ischemic stroke. Purpose To evaluate the prognostic value of CST estimated using recent developed tractometry‐based method. Study Type Prospective. Population Forty‐eight patients with damage induced by stroke lesion who underwent brain magnetic resonance imaging within 7 days from onset. Sequence Diffusion‐weighted ( b = 1000 seconds/mm 2 ) and diffusion kurtosis (DKI)...
Background Noninvasive determination of Notch signaling is important for prognostic evaluation and therapeutic intervention in glioma. Purpose To predict using multiparametric (mp) MRI radiomics correlate with biological characteristics gliomas. Study Type Retrospective. Population A total 63 patients model construction 47 from two public databases external testing. Field Strength/Sequence 1.5 T 3.0 T, T1 ‐weighted imaging ( T1WI ), T2WI , T2 fluid attenuated inversion recovery FLAIR...
Recurrence of lower grade glioma (LrGG) appeared to be unavoidable despite considerable research performed in last decades. Thus, we evaluated the postoperative recurrence within two years after surgery patients with LrGG by preoperative advanced diffusion magnetic resonance imaging (dMRI).
The orthotopic xenograft tumors of human glioma stem cells (GSCs) is a recent model with genotype and phenotypic characteristics close to gliomas. This study aimed explore the imaging immunohistochemical GSCs rats underwent MRI 18F-FDG PET scan in 6th-8th weeks after implantation. morphologic, DWI features tumor lesions were assessed. In addition, tissues further analyzed. Twenty-five identified 20 tumor-bearing rats. On structural MRI, average size was 30.04±17.31mm2, intensity...
Abstract Purpose To compare the efficacy of parameters from mono-, bi- and stretch-exponential diffusion weighted imaging (DWI), tensor (DTI), kurtosis (DKI) neurite orientation dispersion density (NODDI) for prediction IDH1 genotype assessment cell proliferation in gliomas. Methods 91 patients with pathologically confirmed gliomas underwent DWI, multi-b-value DWI DKI/NODDI on 3.0T MRI. The ROIs were manually placed to obtain measurements including apparent coefficient (ADC), slow ADC (D),...