Kyle Troksa

ORCID: 0000-0003-0807-5237
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About
Contact & Profiles
Research Areas
  • DNA Repair Mechanisms
  • Cancer-related Molecular Pathways
  • Mitochondrial Function and Pathology
  • Children's Physical and Motor Development
  • Carcinogens and Genotoxicity Assessment
  • Attention Deficit Hyperactivity Disorder
  • Microtubule and mitosis dynamics

Colorado State University
2012-2014

DNA damage encountered by replication forks poses risks of genome destabilization, a precursor to carcinogenesis. Damage checkpoint systems cause cell cycle arrest, promote repair and induce programed death when is severe. Checkpoints are critical parts the response network that act suppress cancer. perturbation machinery causes stress, characterized accumulation single-stranded bound protein A (RPA), which triggers activation ataxia telangiectasia Rad3 related (ATR) phosphorylation RPA32,...

10.1093/nar/gks849 article EN Nucleic Acids Research 2012-09-12
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