A5004960695- Immunotherapy and Immune Responses
- Glycosylation and Glycoproteins Research
- Global Health and Surgery
- Child and Adolescent Health
- Galectins and Cancer Biology
- Head and Neck Cancer Studies
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- Toxin Mechanisms and Immunotoxins
- HIV/AIDS Research and Interventions
- Global Maternal and Child Health
- Colorectal and Anal Carcinomas
- Signaling Pathways in Disease
- Pharmaceutical studies and practices
- Global Public Health Policies and Epidemiology
- Adolescent Sexual and Reproductive Health
- Transgenic Plants and Applications
- Medicinal Plants and Bioactive Compounds
- Pharmaceutical Economics and Policy
- CRISPR and Genetic Engineering
- Advanced Radiotherapy Techniques
- vaccines and immunoinformatics approaches
- Interprofessional Education and Collaboration
- Cancer Immunotherapy and Biomarkers
- Endometrial and Cervical Cancer Treatments
The University of Texas Rio Grande Valley
2025
Baylor College of Medicine
2015-2023
Texas Children's Hospital
2018-2023
Université Paris Cité
2018
Délégation Paris 5
2018
University of Houston
2017
University of California, Davis
2016
Texas Tech University
2011-2015
Texas Tech University Health Sciences Center
2011-2015
Institute for Women's Policy Research
2014
The neuroprotective activity of the plant Lepidium meyenii (Maca) was studied in two experimental models: vitro and vivo. Crayfish neurons were pretreated with vehicle or pentane extract from Maca, subjected to H(2)O(2), their viability determined microscopically chemically. A significant concentration-neuroprotective effect relationship demonstrated. then administered intravenously rats prior following middle cerebral artery occlusion. While infarct volumes decreased for lower dose, higher...
Germline mutations in the BRCA1 and BRCA2 genes account for 20-25 % of inherited breast cancers about 10 all cancer cases. Detection BRCA mutation carriers can lead to therapeutic interventions such as mastectomy, oophorectomy, hormonal prevention therapy, improved screening, targeted therapies PARP-inhibition. We estimate that African Americans Hispanics are 4-5 times less likely receive despite having similar frequencies non-Jewish Caucasians, who have higher mortality. To begin addressing...
Background: Despite encouraging results from clinical trials and in high-income countries, large-scale data on the effectiveness safety of dolutegravir (DTG) children adolescents living with HIV (CALHIV) are lacking low- middle-income countries (LMICs). Methods: Retrospective analysis was performed among CALHIV 0–19 years old weighing greater than or equal to 20 kg who received DTG 2017 2020 at sites Botswana, Eswatini, Lesotho, Malawi, Tanzania Uganda determine effectiveness, predictors...
It has now ascertained that the clinical manifestations of liver disease in elderly population reflect both cumulative effects longevity on and generalized senescence organism ability to adjust metabolic, infectious, immunologic insults. Although tests are not significantly affected by age, presentation diseases such as viral hepatitis may be subtler than younger patients.Human immunosenescence is a situation which immune system, particularly T lymphocyte function, deteriorates with while...
e16268 Background: Rio Grande Valley (RGV) Hispanic population is a major hotspot for hepatocellular carcinoma (HCC) and liver diseases. HCC often develops from metabolic dysfunction-associated steatotic disease (MASLD), progressing through stages like simple steatosis, MASH, cirrhosis. We explored microbiome-metabolome associations, uncovering microbe-metabolite links in RGV patients that would potentially guiding future diagnostic therapeutic strategies. Methods: DNA extraction was...
Abstract Background Low- and middle-income countries face distinct challenges in providing health care services training. The community of practice (CoP) has been described as a method facilitating much-needed connections conversations on this topic adapted over time to include virtual CoPs. We describe the development evaluation global Clinical Lead Forum (CLF) using CoP framework structure informal continuing professional (CPD) enhance capacity professionals low- countries. Methods Baylor...
Breast carcinoma is a major health issue for millions of women. Current therapies have serious side effects, and are only partially effective in patients with metastatic tumors. Thus, the need novel less toxic urgent. Moreover, hormonal antibody other subtypes not Triple Negative Cancer (TNBC). Immunotherapeutic strategies directed against specific tumor-associated antigens (TAAs) mediated by cytotoxic T lymphocytes (CTL) been largely underexplored this disease. Cancer-testis (CTA) group...
What is known and objective Nephrotoxicity a recognized side effect of cisplatin chemotherapy. However, the optimal strategy for preventing cisplatin-induced nephrotoxicity, if any, remains unclear. The primary this study was to determine whether mannitol or furosemide provides better nephroprotection when administered with hydration prior weekly, low-dose concurrently whole pelvic radiotherapy. Methods Clinical data were abstracted from all women who underwent chemoradiation FIGO IB2-IVA...
e19581 Background: Multiple myeloma (MM) is a neoplastic plasma cell disorder which results in multiple organ failure. Anemia, hypercalcemia, renal failure and skeletal lesions are the most relevant morbidities associated with MM. The treatment of MM includes chemotherapy, hematopoietic stem transplantation, immune modulating treatments proteasome inhibitors. Carfilzomib new inhibitor that also has anti osteoclastogenic effects. Treatment Carfilzomob both cardiac toxicity, mostly mediated by...
// Christopher A. Schutt 1, * , Leonardo Mirandola 2, Jose Figueroa 2 Diane D. Nguyen Joehassin Cordero 3 Klauss Bumm 4 Benjamin L. Judson 1 and Maurizio Chiriva-Internati 5 Division Otolaryngology, Department of Surgery, Yale School Medicine, New Haven, CT, USA Kiromic, Inc., Houston, TX, Otolaryngology (ENT), TTUHSC, Lubbock, CaritasKlinikum Saarbrücken, Germany Multiple Myeloma & Lymphoma, University Texas, MDACC, These authors have contributed equally to this work Correspondence to:...
The Baylor International Pediatric AIDS Initiative (BIPAI) Network supports a network of independent nongovernmental organizations providing health care for children and families in low- middle-income countries (LMIC). Using community practice (CoP) framework, continuing professional development (CPD) program was created professionals to enhance knowledge exchange best practices.