A5102819832- Cytomegalovirus and herpesvirus research
- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Parvovirus B19 Infection Studies
- Neonatal Health and Biochemistry
- Viral Infections and Immunology Research
- Infant Nutrition and Health
- Respiratory viral infections research
- Herpesvirus Infections and Treatments
- Neuroscience of respiration and sleep
- Autophagy in Disease and Therapy
- Neonatal and Maternal Infections
- Congenital Diaphragmatic Hernia Studies
- Spinal Fractures and Fixation Techniques
- S100 Proteins and Annexins
- Educational Assessment and Pedagogy
- Particle Dynamics in Fluid Flows
- Problem and Project Based Learning
- Hepatitis Viruses Studies and Epidemiology
- Pneumonia and Respiratory Infections
- Ocular Diseases and Behçet’s Syndrome
- Immune Cell Function and Interaction
- Erythrocyte Function and Pathophysiology
- Pelvic and Acetabular Injuries
- Inhalation and Respiratory Drug Delivery
XinHua Hospital
2004-2024
Ningbo No.6 Hospital
2019
Shanghai Jiao Tong University
2010-2018
The objective of this study was to measure and compare the macro- micronutrient composition breast milk in urban suburban lactating mothers living Shanghai, China.Primiparous women residing three regions (n= 30/region) a area Shanghai 30) were recruited. Breast samples collected 8-10 days postpartum dietary intake determined.Women from lower socio-economic status as indicated by levels education, occupation income. With exception carbohydrates, all areas had significantly higher...
Human cytomegalovirus (HCMV) is an opportunistic pathogen that causes severe diseases in congenitally infected newborns and immunocompromised patients. Currently, no vaccine available to prevent HCMV infection. Anti-viral drugs are limited by their side effects drug resistance. In this study, performing a medium-sized, anti-HCMV chemical screening, we identified SP600125, CC-401, the c-Jun N-terminal kinase (JNK) inhibitor VIII, three structurally different small molecule JNK inhibitors...
Nebulization is the most widely used respiratory delivery technique with non-invasive properties. However, nebulized drugs often fail to function due excretion and immune clearance of system. In this work, inspired by pollen in nature, novel shell-core aerosol particles (APs) capable Brownian motion are constructed for delivery. Drugs-loaded poly(lactic-co-glycolic acid) nanoparticles prepared emulsification form inner core, membranes macrophages extracted outer shell. The optimized size...
A Content, Context, Connection and Researching, Reasoning, Reflecting (3C3R) model is a conceptual framework for problem-based learning (PBL) problem design. We introduced the 3C3R-PBL method into pediatric teaching plan, evaluated its effectiveness feasibility. The 3C3R was applied in design plan “why lips turn purple when baby crying”. All students were assigned either traditional PBL course or 9-step (3C3R-PBL). performance outcomes of both groups compared. For group, proportion scoring...
Osteopetrosis is a genetic condition of the skeleton characterized by increased bone density caused osteoclast formation and function defects. inherited in form autosomal dominant recessive manner. We report osteopetrosis (ARO; OMIM 611490) Chinese case with history scarce leukocytosis, vision hearing loss, frequent seizures, severe intellectual motor disability. Whole-exome sequencing (WES) followed Sanger revealed novel compound heterozygous mutations chloride channel 7 (CLCN7) gene...
We will discuss a recent case of unexplained neonatal cyanosis, evaluate its origin, clinical presentation, diagnosis, and treatment, share with you some our insights. report transient cyanosis in newborn due to mutation the globulin gene (HBG2), as well diagnosis treatment. Clinically, infant was good overall health, despite low oxygen saturation, arterial partial pressure always normal. Early respiratory support includes mechanical ventilation, nasal tube oxygen, eventually stopping...
Objective To study the occurrence of nosocomial infection (NI)situation in neonatal intensive care unit (NICU)of Xinhua Hospital affiliated to Shanghai Jiaotong University School Medicine from January 2012 October 2013, and analyze risk factors NI. Methods A retrospective was performed NICU, which all neonates hospitalized over 48 hours were included situation NI analyzed. Results This 1 357 neonates, 175 developed 202 times NI.The overall incidence 14.89% (202/1 357), density...
Objective To measure the expressions of microRNAs (miRNA) in peripheral blood infantile hepatitis syndrome(IHS) caused by human cytomegalovirus (HCMV) and analyze relationship between miRNAs Ganciclovir (GCV) effectiveness. Methods Forty-four cases IHS HCMV were recruited from Xinhua Hospital Affiliated to Shanghai Jiaotong University School Medicine as patients group.Patients further grouped into GCV nonsensitive group(n=20) sensitive group(n=24); 15 healthy infants taken control...
Objective: The prophylactic use of phenobarbital for the prevention intraventricular hemorrhage (IVH) in premature infants remains controversial. In order to objectively assess effect on IVH, nine large-scale hospitals participated a nearly two year investigation brain injuries Infants China. Study Design: All with gestational age less than 34 weeks three and 37 other received intravenous (loading dose 20 mg/kg) as early possible before 6 hours age. A maintenance 5 mg/kg daily was given 24...
Objective To study the differences of clinical manifestations, etiology and hospitalized outcomes purulent meningitis in preterm term infants. Method All infants with Hospital from 2006 to 2015 were enrolled this study. The data neonate′s condition, maternal complications, etiology, treatment groups compared. Result During period, 44 118 included. time onset for group was statistically earlier than that [11.2 (3.2, 19.8) d vs. 14.3 (5.6, 23.9) d, P<0.05]. prognosis worse...
Objective To investigate the treatment of infant wheezing during acute phase in pediatric outpatient departments two tertiary hospitals and secondary Shanghai. Methods Simple random sampling method was adopted.Standardized questionnaires were given to parents physicians infants who suffered survey methods (Xinhua Hospital, Shanghai Children′s Medical Center)and (Putuo District People′s Renhe Hospital) from February May 2015 area.All data analyzed by using SPSS 20.0 software.The...
Objective To investigate the effect of leading health education path on clinical nursing patients with atlantoaxial fracture. Methods A retrospective case control study was conducted to analyze 38 fractures admitted our hospital from January 2017 February 2018. There were 31 males and 7 females, aged 21-65 years [(49.6±12.5)years]. In group, there 15 four 25-63 [(48.6±15.3)years]. All underwent posterior pedicle screw fixation. Among in eight atlas fracture, axial seven which five...