Xiaowen Xiang

ORCID: 0000-0003-4312-2676
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About
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Research Areas
  • Neonatal Respiratory Health Research
  • Infant Development and Preterm Care
  • Infant Nutrition and Health
  • Inhalation and Respiratory Drug Delivery
  • Infectious Diseases and Tuberculosis
  • Congenital Diaphragmatic Hernia Studies
  • Tuberculosis Research and Epidemiology
  • Congenital Heart Disease Studies
  • Diagnosis and treatment of tuberculosis
  • Neonatal and fetal brain pathology
  • Hedgehog Signaling Pathway Studies
  • Catalytic Processes in Materials Science
  • Epigenetics and DNA Methylation
  • Particle Dynamics in Fluid Flows

XinHua Hospital
2019-2023

Shanghai Jiao Tong University
2019-2021

Nebulization is the most widely used respiratory delivery technique with non-invasive properties. However, nebulized drugs often fail to function due excretion and immune clearance of system. In this work, inspired by pollen in nature, novel shell-core aerosol particles (APs) capable Brownian motion are constructed for delivery. Drugs-loaded poly(lactic-co-glycolic acid) nanoparticles prepared emulsification form inner core, membranes macrophages extracted outer shell. The optimized size...

10.1002/adma.202207744 article EN Advanced Materials 2023-01-10

Objectives: To investigate the association between serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) level on first day of life and a composite outcome bronchopulmonary dysplasia (BPD) or death in cohort infants born before 32 weeks gestation. Methods: We retrospectively identified gestation who had NT-proBNP levels measured when they were admitted to Neonatal Intensive Care Unit shortly after birth. The BPD was assessed at 36 postmenstrual age. with evaluated. Receiver operator...

10.3389/fped.2019.00166 article EN cc-by Frontiers in Pediatrics 2019-05-07

Abstract Metformin has potential anti‐inflammatory properties and accelerates wound healing by enhancing vascular development. In this study, we aimed to investigate the effects of metformin on pulmonary development underlying mechanism. Newborn mice were subcutaneously injected with from day 2 after exposure hyperoxia. Pulmonary development, inflammation, Shh signaling pathway‐related protein expression evaluated western blotting immunofluorescence staining. M2 macrophage polarization was...

10.1002/iub.2588 article EN IUBMB Life 2021-12-15

Objective: To study the effect of family integrated care (FIC) in neonatal intensive unit (NICU) to development preterm infants at 18 months age. Method: This is a prospective parallel case-control study. Infants FIC group were enrolled previous with gestational age (GA) 28-35 weeks. Study period was from July 2015 2016. Subjects all Department Child Healthcare Third Xiangya Hospital Central South University. control gender, birth weight (BW), BW percentile and days life (DOL) follow-up...

10.3760/cma.j.issn.0578-1310.2016.12.005 article EN PubMed 2016-12-02

Objective To summarize the clinical manifestations, diagnosis and treatment of perinatal tuberculosis. Methods We retrospectively analyzed data six infants with tuberculosis treated in Xinhua Hospital Affiliated to Shanghai Jiao Tong University School Medicine from January 2000 December 2016. Results (1) The patients were at age 27 60 days onset, while mean ages full-term preterm (31±4) (55±6) days, respectively. Three mothers diagnosed active (two which after parturition). (2)...

10.3760/cma.j.issn.1007-9408.2018.08.004 article EN Zhonghua weichan yixue zazhi 2018-08-16
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