A5030509557- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Children's Physical and Motor Development
- Obesity, Physical Activity, Diet
- Physical Activity and Health
- COVID-19 epidemiological studies
- Immune responses and vaccinations
- Oxidative Organic Chemistry Reactions
- Vaccine Coverage and Hesitancy
- Catalysis for Biomass Conversion
- Immune cells in cancer
- Motivation and Self-Concept in Sports
- Birth, Development, and Health
- Neuroinflammation and Neurodegeneration Mechanisms
- Catalytic Processes in Materials Science
- Immunodeficiency and Autoimmune Disorders
- Prenatal Substance Exposure Effects
- Algal biology and biofuel production
- Physical Education and Pedagogy
- COVID-19 Impact on Reproduction
- Influenza Virus Research Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Health and Lifestyle Studies
- Chemical Synthesis and Reactions
- Epigenetics and DNA Methylation
Universidad de Cádiz
2023-2025
Biomedical Research and Innovation Institute of Cadiz
2024-2025
Instituto de Salud Carlos III
2018-2023
Centro Nacional de Microbiologia
2021-2023
University of Victoria
2019
Instituto de Catálisis y Petroleoquímica
2013-2014
BackgroundTo date, no immunological data on COVID-19 heterologous vaccination schedules in humans have been reported. We assessed the immunogenicity and reactogenicity of BNT162b2 (Comirnaty, BioNTech, Mainz, Germany) administered as second dose participants primed with ChAdOx1-S (Vaxzevria, AstraZeneca, Oxford, UK).MethodsWe did a phase 2, open-label, randomised, controlled trial adults aged 18–60 years, vaccinated single 8–12 weeks before screening, history SARS-CoV-2 infection....
The rapid development of mRNA-based vaccines against the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to design accelerated vaccination schedules that have been extremely effective in naive individuals. While a two-dose immunization regimen with BNT162b2 vaccine has demonstrated provide 95% efficacy individuals, effects second dose individuals who previously recovered from natural SARS-CoV-2 infection not investigated detail. In this study, we characterize spike-specific...
ABSTRACT Introduction The aim of this study was to test the feasibility, acceptability, and effectiveness a physically active learning (PAL) intervention (ACTIVE CLASS pilot study) improve physical health cognitive academic performance, increase activity (PA) levels, reduce sedentary time (ST) in adolescents, analyze distribution intensity during PAL lesson assess differences with education lessons. Methods A quasi-experimental conducted including 77 students aged 12–14 yr from two Spanish...
Background: There are no immunological data on SARS-CoV-2 heterologous vaccinations schedules in humans. We assessed the immunogenicity and reactogenicity of BNT162b2 (Comirnaty, BioNTech) administered as second dose participants primed with ChAdOx1-S (Vaxzevria, Astra Zeneca).Methods: did a phase 2, open-label, adaptive, randomised, controlled clinical trial adults under 60 years old, vaccinated single between 8 12 weeks before screening, history infection (EudraCT No. 2021-001978-37...
Background Increasing physical activity (PA) levels and reducing sedentary behaviors in children adolescents is a need, especially schools. Active breaks physically active learning are examples of two emerging methodologies that have been shown to be effective increasing PA additionally produce improvements children’s educational markers. However, the evidence very limited. This paper presents design, measurements, interventions implemented ACTIVE CLASS study, whose objectives are: (i)...
Background Increasing levels of physical activity (PA) and reducing sedentary time among adolescents during the school day is a pressing need. Emerging methodologies strategies been shown to be effective in increasing PA providing additional benefits for students, such us physically active lessons (PAL), breaks (AB) recesses (AR). However, evidence concerning remains limited. This manuscript presents methods rationale MOVESCHOOL study, which aims was examine effects multicomponent...
Long-term hemodialysis (HD) patients are considered vulnerable and at high-risk of developing severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection due to their immunocompromised condition. Since COVID-19 associated mortality rates higher in HD patients, vaccination is critical protect them. The response towards against still uncertain and, particular the cellular immune not fully understood. We monitored humoral responses by analysis serological Spike-specific immunity...
Fetal alcohol spectrum disorder (FASD) is caused by prenatal exposure to ethanol and has been linked neurodevelopmental impairments. Alcohol the potential alter some of epigenetic components that play a critical role during development. Previous studies have provided evidence results in abnormal patterns (i.e., hypomethylation) genome. The aim this study was determine how rats affects hippocampal levels expression two important brain transcriptional regulators involved synaptic plasticity...
Continuous evaluation of the coronavirus disease 2019 (COVID-19) vaccine effectiveness in hemodialysis (HD) patients is critical this immunocompromised patient group with higher mortality rates due to severe acute respiratory syndrome 2 (SARS-CoV-2) infection. The response towards vaccination HD has been studied weeks after their first and second SARS-CoV-2 dose administration, but no further studies have developed a long-term manner, especially including both humoral cellular immune...
The CombiVacS study was designed to assess immunogenicity and reactogenicity of the heterologous ChAdOx1-S/BNT162b2 combination, 14-day results showed a strong immune response. present secondary analysis addresses evolution humoral cellular response up day 180.Between April 24 30, 2021, 676 adults primed with ChAdOx1-S were enrolled in five hospitals Spain, randomised receive BNT162b2 as second dose (interventional group [IG]) or no vaccine (control [CG]). Individuals from CG received also...
The rapid development and deployment of mRNA-based vaccines against the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to design accelerated vaccination schedules that have been extremely effective in naïve individuals. While a two-dose immunization regimen with BNT162b2 vaccine has demonstrated provide 95% efficacy individuals, effects second dose individuals who previously recovered from natural SARS-CoV-2 infection not investigated detail. Here we characterized,...
Abstract Background: Physical inactivity and sedentary levels among children adolescents are significant concerns. The school setting presents an ideal scenario for implementing strategies aimed at improving physical activity (PA) reducing behaviours. However, most of the interventions have primarily focused on children, limited evidence is available adolescents. This paper design, measurements, implemented in ACTIVE CLASS study, which aim to assess effects two PA levels, time,...
Background: The CombiVacS study was designed to assess immunogenicity and reactogenicity of the heterologous ChAdOx1-S/BNT162b2 combination, 14-day results showed a strong immune response. present secondary analysis addresses evolution humoral cellular response up day 180. Methods: 676 adult subjects primed with ChAdOx1-S were randomised receive BNT162b2 as second dose (interventional group [IG]) or no vaccine (control [CG]). Subjects from CG received also on 28, planned based favourable 14....