A5037920513- Microfluidic and Capillary Electrophoresis Applications
- Microfluidic and Bio-sensing Technologies
- Biosensors and Analytical Detection
- Advanced Chemical Sensor Technologies
- Methemoglobinemia and Tumor Lysis Syndrome
- Gas Sensing Nanomaterials and Sensors
- Tuberculosis Research and Epidemiology
- Respiratory Support and Mechanisms
- Nephrotoxicity and Medicinal Plants
- 3D Printing in Biomedical Research
- Intestinal and Peritoneal Adhesions
- Medical Imaging and Pathology Studies
- Mass Spectrometry Techniques and Applications
- Neonatal Respiratory Health Research
- Metabolomics and Mass Spectrometry Studies
- Congenital Diaphragmatic Hernia Studies
- Acute Kidney Injury Research
- Drug-Induced Adverse Reactions
- Potassium and Related Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pneumonia and Respiratory Infections
- Intensive Care Unit Cognitive Disorders
- Single-cell and spatial transcriptomics
- Infectious Diseases and Tuberculosis
- Analytical Chemistry and Sensors
National Taiwan University Hospital
2014-2023
National Yang Ming Chiao Tung University
2014-2020
National Hsinchu University of Education
2020
(1) Background: Lung cancer is silent in its early stages and fatal advanced stages. The current examinations for lung are usually based on imaging. Conventional chest X-rays lack accuracy, computed tomography (CT) associated with radiation exposure cost, limiting screening effectiveness. Breathomics, a noninvasive strategy, has recently been studied extensively. Volatile organic compounds (VOCs) derived from human breath can reflect metabolic changes caused by diseases possibly serve as...
Abstract Peripheral blood lymphocytes (PBLs) are mature that circulate in the rather than being localized to organs. A reliable label-free collection approach can viably and appropriately isolate PBLs establish vitro culture systems is crucial for basic research clinical requirements. However, isolation of from whole difficult, so development a rapid safe method perform this task required. Microfluidic technology offers opportunities challenge performance macroscale methods. In study, we...
Lung cancer is one of the leading causes death worldwide.
Blood tests provide crucial diagnostic information regarding several diseases. A key factor that affects the precision and accuracy of blood is interference red cells; however, conventional methods separation are often complicated time consuming. In this study, we devised a simple but high-efficiency system on self-strained microfluidic device separates 99.7 ± 0.3% plasma in only 6 min. Parameters, such as flow rate, design filter trench, relative positions trench channel, were optimized...
Acute kidney injury (AKI) is occasionally detected in patients receiving anti-tuberculosis (TB) treatment. This prospective cohort study the first to investigate incidence, risk factors, and renal outcomes of AKI during anti-TB was conducted from January 1, 2016, May 31, 2018. Patients with a new diagnosis TB on standard treatment were enrolled, received regular laboratory monitoring. defined according Kidney Disease: Improving Global Outcome (KDIGO) criteria. Urinalysis, ultrasonography,...
The study was carried out on elderly nursing home residents in Taiwan. We assessed whether the serial QuantiFERON-TB Gold (QFT-G) assay and tuberculin skin test (TST) were reliable tools to predict or exclude development of active tuberculosis (TB).This prospective observational cohort involved non-bacillus Calmette-Guérin-vaccinated 259 free TB at baseline. Of these, 147 eligible for follow up. Participants underwent QFT-G TST baseline 2-year up, monitored over 5 years. Agreement between...
Enzyme-linked immunosorbent assays (ELISAs) are tests that uses antibody recognition and enzyme catalytic activity to identify a substance, they have been widely used as diagnostic tool in the clinic.
Background: Comprehensive rehabilitation programs are recommended for patients with prolonged mechanical ventilation (PMV) to facilitate functional recovery and ventilator weaning, but whether the status after influences outcome has not been clearly evaluated. This study aimed investigate association between post-rehabilitation weaning survival in PMV patients. Methods: We retrospectively enrolled admitted respiratory care center (RCC), a post-ICU facility protocolized program, from January...
A 62-year-old man with a history of coronary artery disease, hypertension and diabetes mellitus was admitted to respiratory care unit for chronic failure after an episode life-threatening myocardial infarction. The hospital course complicated presumed intra-abdominal infection the presentation fever, abdominal pain muscle guarding. An emergent non-contrast CT abdomen pelvis showed much faecal material high density in small large intestines (figure 1, arrows) resultant bowel loop dilation,...
Abstract Blood tests provide crucial diagnostic information regarding several diseases. A key factor that affects the precision and accuracy of blood is interference red cells; however, conventional methods separation are often complicated time consuming. In this study, we devised a simple but high-efficiency system on self-strained microfluidic device separates 99.7% plasma in only 6 min. Parameters, such as flow rate, design filter trench, relative positions trench channel, were optimized...
Aims: Acute kidney injury (AKI) is occasionally detected in patients receiving anti tuberculosis (TB) treatment. This prospective cohort study the first to investigate true incidence, risk factors, and renal outcomes. Methods: was conducted from January 1, 2016, May 31, 2018, with a new diagnosis of TB standard anti-TB treatment were enrolled; received regular laboratory monitoring. AKI defined according Kidney Disease: Improving Global Outcome (KDIGO) criteria. Urinalysis, measurements for...