A5020048277- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Intensive Care Unit Cognitive Disorders
- Frailty in Older Adults
- Anesthesia and Pain Management
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Nutrition and Health in Aging
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Traumatic Brain Injury and Neurovascular Disturbances
- Mobile Health and mHealth Applications
- Delphi Technique in Research
- Enhanced Recovery After Surgery
- Trauma Management and Diagnosis
- Lung Cancer Diagnosis and Treatment
- Nitric Oxide and Endothelin Effects
- Pediatric Pain Management Techniques
- Neonatal Respiratory Health Research
- Healthcare Decision-Making and Restraints
- Clinical Nutrition and Gastroenterology
Siriraj Hospital
2015-2025
National Science and Technology Development Agency
2025
Ramathibodi Hospital
2025
Mahidol University
2015-2024
Chulalongkorn University
2014
University of Washington
2010-2011
Abstract Background As societies age, increasing numbers of older adults undergo surgeries with anesthesia. Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) frequently occur in surgical patients. Most these patients already have preoperative mild impairment (MCI). However, the correlation between MCI POD remains unclear. This study aimed to determine incidence elderly without preexisting MCI. Methods A prospective enrolled aged 60 years above scheduled for major...
Abstract Background Perioperative neurocognitive disorder includes postoperative cognitive dysfunction (POCD) and delirium (POD). Concerning inconclusive consequences of POCD compared with POD, we explored the association between either or POD functional decline as well healthcare utilization. Methods Patients aged at least 60 years who underwent a major operation were enrolled. was defined decrease in Montreal Cognitive Assessment (MoCA) score (≥ 2) 1 week after surgery. Postoperative (POD)...
Polypharmacy, which is defined as the use of 5 or more medications, can exert significant adverse impact on older adult patients. The objective this study was to determine prevalence polypharmacy, and investigate its association with postoperative cognitive dysfunction (POCD) in patients who underwent elective major surgery at Siriraj Hospital-Thailand's largest national tertiary referral center.This prospective included aged ≥65 years were scheduled for during December, 2017 2019 period....
Decreases in endothelial nitric oxide synthase derived (NO) production during liver transplantation promotes injury. We hypothesized that preemptive inhaled NO (iNO) would improve allograft function (primary) and reduce complications post-transplantation (secondary). Patients at two university centers (Center A B) were randomized to receive placebo (n = 20/center) or iNO (80 ppm, n the operative phase of transplantation. Data analyzed set intervals for up 9-months compared between groups....
Multimorbidity (≥2 chronic illnesses) is a worldwide healthcare challenge. Patients with multimorbidity have reduced quality of life and higher mortality than healthy patients use resources more intensively. This study investigated the prevalence multimorbidity; examined effects on utilization; costs compared associations between health-related (HRQoL) older undergoing surgery multimorbidity, Charlson Comorbidity Index (CCI), Simple Frailty Questionnaire (FRAIL), American Society...
Objectives. To determine the overall mortality and risk factors of COVID-19 patients who were admitted to Home Isolation (HI) program in Bangkok, Thailand, during epidemic crisis 2021. Methods. We conducted a retrospective cohort study using data from government telehealth application July December The vital status was verified database on September 20, 2022. used survival analysis analyze 28-day independently associated factors. Results. Of 90 854 reported cases, average age 37.27 years,...
"The most important thing is to strive towards a goal which not immediately visible. That the concern of mind, but spirit" —Antoine de Saint-Exupery, Flight Arras, 1942 Methodologies for cardiac output determination in critically ill children intensive care setting have been both difficult and unfulfilling. The methodologies include invasive, semi-invasive, noninvasive methodologies. clinical standard, one best known invasive methodologies, pulmonary artery thermodilution technique,...
Background A predictive model of scores difficult intubation (DI) may help physicians screen for airway difficulty to reduce morbidity and mortality in obese patients. The present study aimed set up evaluate the performance a newly developed, practical, multivariate DI Methods prospective multi-center was undertaken on adults with body mass index (BMI) 30 kg/m2 or more who were undergoing conventional endotracheal intubation. BMI 10 preoperative tests (namely, malformation teeth upper jaw,...
Ischemia reperfusion injury (IRI) is an inevitable clinical consequence in organ transplantation. It can lead to early graft nonfunction and contribute acute chronic rejection. Advanced molecular biology has revealed the highly complex nature of this phenomenon few definitive therapies exist. This paper reviews factors involved pathophysiology IRI potential ways attenuate it. In recent years, inhaled nitric oxide, carbon monoxide, hydrogen sulfide have been increasingly explored as plausible...
The use of supplemental oxygen in uncomplicated cesarean deliveries under spinal anesthesia has been thoroughly investigated during recent decades. aim this study was to determine the benefits for both mother and infant administering supplemental, low-dose via a nasal cannula versus having no supplement (i.e., room air only). Healthy parturients at term undergoing elective section were randomly allocated into two groups: an group (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Several methods are available for identifying frailty, but limited tools have been validated in Thai context. Our objective was to evaluate the validity and reliability of version Simple Frailty Questionnaire (T- FRAIL) compared Index (TFI) explore modifications improve its diagnostic properties.The T-FRAIL translated with permission using a standardized protocol, that included forward back-translation. Content analysis performed input from 5 geriatricians. Test-retest reliability,...
Objective: This study aimed to assess the prevalence of obesity and identify associated health problems behaviors among monks residing in Bangkok Noi its adjacent districts. Materials Methods: Employing a cross-sectional design, this research incorporated self-report questionnaires specialized checkup programs at university hospital. Eligible participants were aged 20 years or older, living permanently temples within District Monks shortterm ordination excluded. Data collection occurred...
Summary Aim To report our institutional experience with intraoperative jugular venous oximetry during pediatric intracranial surgery to guide anesthetic care. Background The utility of in adults undergoing is well known. However, there a little information on its' application children surgery. Methods After IRB approval, we examined patient, equipment, placement, and sampling characteristics for bulb catheters aged <18 years who were monitored elective between 2006 2010. We also...
Background . Few investigations preoperatively are important for low-risk patients. This study was designed to determine the level of compliance with preoperative investigation guidelines ASA I patients undergoing elective surgery. Secondary objectives included following: identify common inappropriate investigations, evaluate impact abnormal testing on patient management, factors affecting noncompliant tests, and estimate unnecessary expenditure. Methods retrospective conducted adult over a...
The aim of this study is to establish the prevalence, associated factors, and clinical impact delirium in newly referred palliative care patients percentage diagnoses missed by primary medical teams.
The incidence of postoperative pulmonary complications (PPCs) is increasing in line with the rise number surgical procedures performed on geriatric patients. In this study, we determined and risk factors PPCs elderly Thai patients who underwent upper abdominal procedures, investigated whether Assess Respiratory Risk Surgical Patients Catalonia (ARISCAT) score helps to predict Thais.A retrospective study was conducted aged over 65 years had been admitted ward Siriraj Hospital, Mahidol...
Objective: Warfarin is extensively used as an oral anticoagulant; however, its clinical application complicated by a narrow therapeutic index. This investigation evaluated the efficacy of drug reminder versus traditional care in facilitating patients’ maintenance range, well stabilizing time range (TTR). Material and Methods: A single-blind randomized controlled trial recruited 40 warfarin users (≥3 months) with stable INR for 6 months. The intervention group received smartphone app...