A novel sol−gel method is described for the preparation of solid-phase microextraction (SPME) fibers. The protective polyimide coating was removed from a 1-cm end segment 200 μm o.d. fused-silica fiber, and exposed outer surface coated with bonded layer poly(dimethylsiloxane) (PDMS). chemistry behind this technique presented. Efficient SPME-GC analyses polycyclic aromatic hydrocarbons, alkanes, aniline derivatives, alcohols, phenolic compounds in dilute aqueous solutions were achieved using...

Sol-gel chemistry was used to prepare porous monolithic columns for capillary electrochromatography. The developed sol-gel approach proved invaluable and generates in a simple rapid manner. Practically any desired column length ranging from few tens of centimeters meters may be readily obtained. incorporation the precursor, N-octadecyldimethyl[3-(trimethoxysilyl)propyl]ammonium chloride, into sol solution critical as this reagent possesses an octadecyl moiety that allows chromatographic...

Sol-gel capillary microextraction (sol-gel CME) is introduced as a viable solventless extraction technique for the preconcentration of trace analytes. To our knowledge, this first report on use sol-gel-coated capillaries in analytical microextraction. Sol-gel-coated were employed and wide variety polar nonpolar Two different types sol-gel coatings used extraction: poly(dimethylsiloxane) (PDMS) poly(ethylene glycol) (PEG). An in-house-assembled gravity-fed sample dispensing unit was to...

A sol−gel chemistry-based novel approach to column technology for high-resolution capillary gas chromatography is described that effectively combines surface treatment, deactivation, coating, and stationary phase immobilization into a single step. In the conventional approach, these operations are carried out in separate steps make fabrication time-consuming job. new cleaned fused silica filled with sol solution of appropriate composition, reactions allowed go on inside controlled period,...

Abstract A new, reproducible method is described for the preparation of highly efficient fused silica packed capillary columns using pressure programmed liquid or supercritical carbon dioxide to carry packing material into capillary. The allows facile long, uniformly capable producing over 240,000 theoretical plates in SFC. Columns up 10 meters length were prepared LC materials different chemical nature and particle size. new does not require a separate step preparing slurry, it free from...

Desirable cost and removal effectiveness of the adsorbents can be obtained by use modification agricultural waste products. Therefore, in this study rice husk (RH), char (RHC) chemically modified (CMRHC) were prepared used as for Congo Red dye from aqueous media under different experimental conditions. It was observed that adsorption not only affected with types but also other variables such time, adsorbent dose, concentration, pH temperature. Thermodynamics indicated on three is spontaneous...

Abstract The separation and detection of complexes aptamers protein targets by capillary electrophoresis (CE) with laser‐induced fluorescence was examined. Aptamer‐thrombin aptamer‐immunoglobulin E (IgE) were used as model systems. Phosphate, 3‐( N ‐morpholino)propanesulfonic acid phosphate, tris(hydroxyamino)methane‐glycine‐potassium (TGK) buffer at pH 8.4 tested media. Buffer had a large effect TGK providing the most stable for both protein‐aptamer complexes. Conditions that suppressed...

Sol−gel chemistry was successfully used for the fabrication of open tubular columns with surface-bonded octadecylsilane (ODS) stationary-phase coating capillary electrochromatography (OT-CEC). Following column preparations, a series experiments were performed to investigate performance sol−gel coated ODS in OT-CEC. The incorporation N-octadecyldimethyl[3-(trimethoxysilyl)propyl]ammonium chloride as one precursors played an important role electrochromatographic prepared columns. This chemical...

Germania-based, sol−gel hybrid organic−inorganic coatings were developed for capillary microextraction and gas chromatography (GC). Being an isostructural analogue of SiO2, GeO2 is compatible with the silica network. Because this similarity, germania-based materials possess great potential being used in areas chromatographic separation sample preparation. These possibilities, however, remain practically unexplored. To our knowledge, first instance that a material as sorbent analytical...

Objective: The present study is an attempt to develop and evaluate the sustained release tablet formulations (oral) of pantoprazole sodium utilizing chitosan (CH) based in situ forming polyelectrolyte complex as retardant polymer. Methods: traditional method wet granulation was used create various employing a 1% w/w solution CH acetic acid (cooled about 4°C neutralized) binder. formulation optimized using two-factor, three-level face-centered Central Composite Design. Design-Expert software...

A sol-gel chemistry-based method was developed for the preparation of highly stable capillary gas chromatography (GC) columns with surface-bonded poly(ethylene glycol) (PEG) stationary phase. Through a single-step procedure, it concurrently provided column deactivation, stationary-phase coating, and chemical immobilization coated film. Sol-gel reactions were carried out within fused-silica capillaries that filled properly designed sol solutions containing two precursors, different...