- Multiple Myeloma Research and Treatments
- Heart Failure Treatment and Management
- Pericarditis and Cardiac Tamponade
- Diabetes Treatment and Management
- Cancer Treatment and Pharmacology
- Acute Myocardial Infarction Research
- Protein Degradation and Inhibitors
- Vascular anomalies and interventions
- Urticaria and Related Conditions
- Pharmaceutical Practices and Patient Outcomes
- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Blood Pressure and Hypertension Studies
- Autoimmune Bullous Skin Diseases
- Peripheral Neuropathies and Disorders
- Cardiac Structural Anomalies and Repair
- Psoriasis: Treatment and Pathogenesis
- Medication Adherence and Compliance
- Brain Metastases and Treatment
- Cardiac and Coronary Surgery Techniques
- Intramuscular injections and effects
- Analytical Methods in Pharmaceuticals
- Cardiovascular Conditions and Treatments
- Meningioma and schwannoma management
- Systemic Sclerosis and Related Diseases
Nethradhama Superspeciality Eye Hospital
2024
Care India
2024
University of California, Riverside
2020-2024
Narayana Health
2024
All India Institute of Medical Sciences
2023
All India Institute of Medical Sciences Bhopal
2023
All India Institute of Medical Sciences Raipur
2023
Max Super Speciality Hospital
2018-2022
Max Healthcare
2021
Post Graduate Institute of Medical Education and Research
2004-2007
Calcium channel blockers (CCBs) have been recommended as the first-line treatment option for management of hypertension. Amlodipine has used to treat hypertension over past 3 decades. However, chief limitation amlodipine is pedal edema; it associated with poor adherence therapy. a racemic mixture two stereoisomers [R(+), S(-)]. Only S(-) isomer exerts vasodilating action. The R-amlodipine considered cause adverse effects. To understand place S-amlodipine and its combinations in related...
Abstract Background: Worsening heart failure (WHF) is characterized by the progression of symptoms in patients with established HF, necessitating intensified treatment, typically diuretics. Outpatient (OP) management WHF offers an alternative to hospitalization, as many experience a gradual onset symptoms, allowing timely intervention. However, OP often underrecognized and excluded from clinical trials, highlighting need for structured guidance. This expert consensus aims address this gap...
Psoriasis is an immune-mediated chronic inflammatory disorder of the skin. Association with kidney disease has been debated for a long time. Secondary renal amyloidosis in psoriatic arthropathy and drug-induced lesions secondary to methotrexate or cyclosporine are accepted accompaniments psoriasis. IgA nephropathy also known occur psoriatics. We report three interesting cases involvement long-standing established psoriasis on topical therapy alone. The patients presented hypertension,...
Abstract Pigmentation of skin, nails and mucosae has frequently been described in HIV positive patients. Various causes for this phenomenon have ascribed, which include intake various drugs like zidovudine, opportunistic infections toxoplasmosis adrenocortical suppression. However, there no uniform explanation. We describe three AIDS patients with different personal disease profiles but essentially the same pattern pigmentation. This pigmentation is thereby discussed. also propose that could...
Psoriasis is an immune-mediated chronic inflammatory disorder of the skin. Association with kidney disease has been debated for a long time. Secondary renal amyloidosis in psoriatic arthropathy and drug-induced lesions secondary to methotrexate or cyclosporine are accepted accompaniments psoriasis. IgA nephropathy also known occur psoriatics. We report three interesting cases involvement long-standing established psoriasis on topical therapy alone. The patients presented hypertension,...
The human immunodeficiency virus (HIV) pandemic is nearly 20 years old. HIV infection characterized by profound resulting in an increased incidence of opportunistic infections and neoplasms. However, the greatest paradox occurrence certain autoimmune disorders setting HIV. These include diffuse interstitial lymphocytosis syndrome (DILS), reactive arthritis, systemic lupus erythematosus (SLE), rheumatoid arthritis (RA). It has also been seen that even absence these well‐defined diseases,...
Nephrotic syndrome can be associated with various neoplasms, especially solid tumors and lymphomas. This patient presented painless hematuria of transitional cell carcinoma urinary bladder, underwent transurethral resection, but developed recurrence 16 months later. Repeat resection was done intravesical Bacillus Calmette-Guerin (BCG) injections were started. After six months, the hypertension nephrotic a biopsy revealing membranous glomerulonephritis, though there no radiological evidence...
Worsening heart failure (WHF) is a distinct under-diagnosed and under-treated condition, independent of location care. Heart (HF) progression punctuated by repeated WHF events, each resulting in reduced cardiac function. One-third the patients with HF ejection fraction experience decompensation event. These events often result emergency department visits hospitalization. Despite its inclusion recent guidelines, there no precise definition or various forms. It worth noting that signals need...
Abstract A 19‐year‐old female patient of lepromatous leprosy with Type II reaction, on multidrug therapy and prednisolone, presented acute onset flaccid quadriparesis. The cerebrospinal fluid examination revealed albumino‐cytologic dissociation. Nerve biopsy showed infiltration lepra bacilli, features vasculitis, demyelination. There were no other identifiable precipitating factors for Guillain Barre Syndrome in this patient. Her condition improved without any steroid therapy. This case...
Heart failure (HF) is a global health concern that prevalent in India as well. HF reported at younger age Indian patients with comorbidity of type 2 diabetes (T2DM) approximately 50% patients. Sodium-glucose cotransporter-2 inhibitors (SGLT2i), originally approved for T2DM, are new guideline-recommended and treatment strategies HF. Extensive evidence highlights SGLT2i exhibits profound cardiovascular (CV) benefits beyond glycemic control. SGLT2i, conjunction other guideline-directed medical...
Chronic kidney disease (CKD) is a major contributor to morbidity and mortality in India. CKD often coexists with heart failure (HF), diabetes, hypertension. All these comorbidities are risk factors for renal impairment. HF pathophysiologically intertwined, the deterioration of one can worsen prognosis other. There need safe pharmacological therapies that target both also useful hypertension diabetes. Neurohormonal activation achieved through sympathetic nervous system (SNS),...
Background: Type 2 diabetes mellitus (T2DM) is a prevalent condition, with significant burden in India, affecting approximately 74.2 million individuals. Vildagliptin, selective dipeptidyl peptidase 4 (DPP-4) inhibitor, approved globally for monotherapy and combination therapy. Recently, it became available as generic product, which increased its accessibility to patients. This study aimed assess the knowledge, attitude, practice (KAP) regarding vildagliptin T2DM management. Methods: A...
The incidence of heart failure (HF) in India is estimated to be 0.5-1.7 cases per 1,000 people year, and approximately 4,92,000-1.8 million new are detected every year. Despite the high rate mortality associated with HF, most patients do not receive maximal guideline-directed medical therapy (GDMT). Current guidelines advocate early multidrug combination four classes drugs, namely, beta-blockers (BBs), mineralocorticoid receptor antagonists (MRAs), angiotensin receptor-neprilysin inhibitors...
Anomalous origin of the right coronary artery from ascending aorta above left sinus Valsalva is a very rare anomaly, which can pose extreme difficulties for operator, especially in setting an acute myocardial infarction. Herein, we describe patient with this anomaly whom computed tomography angiographic guidance was used to identify its presence and perform successful angioplasty inferior wall infarction complicated by 2:1 atrioventricular block.