A5074081266- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Pelvic floor disorders treatments
- Schizophrenia research and treatment
- Antibiotic Use and Resistance
- Mental Health Treatment and Access
- Mental Health and Psychiatry
- Pneumonia and Respiratory Infections
- Emergency and Acute Care Studies
- Primary Care and Health Outcomes
- Health Policy Implementation Science
- Influenza Virus Research Studies
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Evolution and Genetic Dynamics
- Blood Pressure and Hypertension Studies
- Diabetes Management and Education
- Pain Management and Opioid Use
- Prostate Cancer Treatment and Research
- Urinary Tract Infections Management
- Bariatric Surgery and Outcomes
- Respiratory viral infections research
- Body Contouring and Surgery
- Total Knee Arthroplasty Outcomes
- Mathematical and Theoretical Epidemiology and Ecology Models
Lawson Health Research Institute
2013-2025
London Health Sciences Centre
2021-2025
Institute for Clinical Evaluative Sciences
2018-2025
Western University
2014-2024
Western University of Health Sciences
2024
International Council for the Exploration of the Sea
2023
New York Hospital Queens
2022
Columbia University
2022
San Jose State University
2022
NewYork–Presbyterian Hospital
2022
Experimental designs that take advantage of high-throughput sequencing to generate datasets include RNA (RNA-seq), chromatin immunoprecipitation (ChIP-seq), 16S rRNA gene fragments, metagenomic analysis and selective growth experiments. In each case the underlying data are similar composed counts reads mapped a large number features in sample. Despite this similarity, methods used for these experimental all different, do not translate across Alternative have been developed physical...
We determined the performance of PCA3 alone and in presence other covariates as an indicator contemporaneous future prostate biopsy results a population with previous negative increased serum specific antigen.Urine scores were before year 2 4 biopsies from patients placebo arm REDUCE trial, cancer risk reduction study evaluating men moderately antigen at baseline. PCA3, percent free correlated outcome via univariate logistic regression ROC analyses. Multivariate was also performed including...
It is unclear whether arthroscopic resection of degenerative knee tissues among patients with osteoarthritis (OA) the delays or hastens total arthroplasty (TKA); opposite findings have been reported.
This paper highlights embarrassment as one of the often-ignored emotions young people when it comes to discussing issues around sexual health. There have been many health studies on knowledge, attitudes and behaviour over past two decades, but emotional aspects largely ignored, despite a growing literature in sociology emotion. A qualitative approach was adopted form focus group discussions, which included questions sex education, campaigns formal informal sources information advice. Focus...
Despite increased focus in New Zealand on reducing health inequities between Māori and European ethnic groups, research barriers facilitators to primary healthcare access for remains limited. In particular, there has been little interrogation of the significance social-assignment ethnicity relation engagement with predominantly non-Māori services providers. A qualitative study was undertaken a subsample (n = 40) broader Hauora Manawa Study examine experiences accessing engaging among adult...
Importance Post–cancer therapy kidney outcomes, including chronic disease (CKD) and hypertension, are common in childhood cancer survivors (CCS). The incidence timing of CKD hypertension CCS compared with other at-risk or general populations unclear. Objective To determine the association treatment post–cancer hypertension. Design, Setting, Participants Population-based matched cohort study children treated for between April 1993 March 2020 Ontario, Canada, follow-up until 2021. (exposed)...
Although early detection and management of excess rates gestational diabetes mellitus (GDM) among Indigenous women can substantially reduce maternal offspring complications, current interventions seem ineffective for women. While undertaking a qualitative study in rural community Northland, New Zealand about the complexities living with diabetes, we observed common emotional discourse burden diabetic pregnancies. Given significance GDM our commitment to give voice Māori ways that could...
Abstract We investigate the fate of de novo mutations that occur during in-host replication a pathogenic virus, predicting probability such are passed on disease transmission to new host. Using influenza A virus as model organism, we develop life-history within-host dynamics infection, deriving multitype branching process with coupled deterministic capture population available target cells. quantify neutral and affecting five traits: clearance, attachment, budding, cell death, eclipse phase...
Abstract Background With 90% of all antibiotics in Canada being used the community setting, tracking outpatient prescribing is integral to mitigate issue antimicrobial resistance. In 2005, a provincial programme was launched British Columbia (BC) disseminate information regarding judicious use antibiotics. These efforts include educational campaigns, updated practitioner guidelines and academic detailing. The impact stewardship on requires ongoing evaluation. Objectives This study examines...
Background and Purpose: Physical activity (PA) has many known benefits for people with Parkinson disease (PD); however, do not meet recommended levels of frequency or intensity. We designed Engage-PD , a PA coaching program delivered via telehealth grounded in self-determination theory to promote uptake facilitate exercise self-efficacy disease. This study aimed determine the feasibility preliminary efficacy explore whether baseline characteristics were associated outcomes. Methods: A single...
Background and objectives Radiofrequency ablation (RFA) is a common treatment modality for chronic axial spine pain. Controversy exists over its effectiveness, outcomes in real-world setting have not been evaluated despite increasing use of RFA. This study examined changes healthcare utilization opioid after RFA Ontario, Canada. Methods retrospective cohort was conducted Ontario using administrative data. residents receiving their initial between 1 January 2009 31 March 2015 were included....
Type 2 diabetes mellitus (T2DM) and its complications are more common among Māori Pacific people compared with other ethnic groups in New Zealand. Comprehensive sustained approaches that address social determinants of health required to this condition, including culturally specific interventions. Currently, Zealand has no comprehensive T2DM management programme for or people.The Mana Tū was developed by a Māori-led collaborative primary healthcare workers researchers, codesigned whānau...
This qualitative study explored self‐reported experiences of primary healthcare among a sample urban Māori adults. paper specifically focuses on the theme relational continuity care identified in participant discussions access and engagement with their predominantly non‐Māori general practitioners (GPs). The involved purposively selected subsample (n=42) Christchurch cohort Hauora Manawa Community Heart Study (n=244). Participants took part in‐depth interviews, which were transcribed...
Community-based hybrid cardiac rehabilitation (CR) programs offer a viable alternative to conventional centre-based CR, however their long-term benefits are unknown. We conducted secondary analysis of the CR Participation Study in London, Ontario, between 2003 and 2006. eligible patients hospitalized for major event, who resided within 60 min, were referred program; 381 544 (64%) initiated CR; an additional 1,498 not due distance. For present study, participants matched using propensity...