Luca Gallelli

ORCID: 0000-0003-0858-7902
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About
Contact & Profiles
Research Areas
  • Asthma and respiratory diseases
  • Epilepsy research and treatment
  • Pharmacological Effects and Toxicity Studies
  • Pharmacovigilance and Adverse Drug Reactions
  • Migraine and Headache Studies
  • Urinary Bladder and Prostate Research
  • Pharmaceutical studies and practices
  • Diagnosis and Treatment of Venous Diseases
  • Acute Ischemic Stroke Management
  • Wound Healing and Treatments
  • Drug-Induced Adverse Reactions
  • Pain Mechanisms and Treatments
  • Inflammatory mediators and NSAID effects
  • Venous Thromboembolism Diagnosis and Management
  • Pharmaceutical Practices and Patient Outcomes
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • SARS-CoV-2 and COVID-19 Research
  • Neurological and metabolic disorders
  • MicroRNA in disease regulation
  • Osteoarthritis Treatment and Mechanisms
  • Cerebrovascular and Carotid Artery Diseases
  • Lipoproteins and Cardiovascular Health
  • Respiratory and Cough-Related Research
  • COVID-19 Clinical Research Studies
  • Vitamin D Research Studies

Magna Graecia University
2016-2025

First Affiliated Hospital of Xiamen University
2025

Soochow University
2025

Taizhou First People's Hospital
2025

Azienda Ospedaliero Universitario Mater Domini
2015-2024

University of Campania "Luigi Vanvitelli"
2024

Department of Medical Sciences
2015-2024

University of Verona
2021-2023

University of Calabria
2019-2022

Yantai University
2019-2022

Abstract Venous ulcers are related to dysfunctions in extracellular matrix. Both matrix metalloproteinases ( MMP ) and neutrophil gelatinase‐associated lipocalin NGAL could play a role the healing process patients with chronic venous ulcers. We evaluated of ‐9 ulceration. performed an open‐label, parallel groups, single clinical center study. Patients leg represented test group (Group I ), whereas without control II ). In Group plasma wound fluid samples were collected at time admission,...

10.1111/wrr.12035 article EN Wound Repair and Regeneration 2013-03-26

Abstract Wound healing, especially diabetic ones, is a relevant clinical problem, so it not surprising that surgical procedures are often needed. To overcome invasive procedures, several strategies with drugs or natural compound used. Recently, in an experimental study, we described increase keratinocyte proliferation after their exposition to quercetin plus oleic acid. In the present evaluated both efficacy and safety of nano‐hydrogel embedded acid treatment lower limb skin wound patients...

10.1111/iwj.13299 article EN other-oa International Wound Journal 2019-12-25

Evaluate the role of platelet-rich fibrin (PRF) as a natural carrier for antibiotics delivery through analysis drug release and antimicrobial activity.PRF was prepared according to L-PRF (leukocyte- fibrin) protocol. One tube used control (without drug), while an increasing amount gentamicin (0.25 mg, G1; 0.5 G2; 0.75 G3; 1 G4), linezolid (0.5 L1; L2; 1.5 L3; 2 L4), vancomycin (1.25 V1; 2.5 V2; 3.75 V3; 5 V4) added other tubes. At different times supernatant collected analyzed. Strains E....

10.1186/s12903-023-02814-5 article EN cc-by BMC Oral Health 2023-03-09

Cigarette smoke (CS) is a driver of many respiratory diseases, including chronic obstructive pulmonary disease (COPD) and non-small cell lung cancer (NSCLC). Tobacco causes oxidative stress, impaired phagocytosis alveolar macrophages (AMs), alterations in gene expression the lungs smokers. MicroRNAs (miRNAs) are small non-coding RNAs that influence several regulatory pathways. Previously, we monitored expressions hsa-miR-223-5p, 16-5p, 20a-5p, -17-5p, 34a-5p, 106a-5p AMs derived from...

10.3390/ijms26031277 article EN International Journal of Molecular Sciences 2025-02-01

Abstract Venous ulcers are common, with an overall prevalence of up to 2% in the general population western countries, and have significant socioeconomic impact. Matrix metalloproteinases ( MMP s) involved alteration extracellular matrix that could lead venous ulceration. Sixty‐four patients were recruited a 22‐month period. All subjected most appropriate treatment considering also patient's wishes (compression therapy followed or not by vein surgery). Patients randomised into two groups 32...

10.1111/iwj.12077 article EN other-oa International Wound Journal 2013-04-05

Alterations of the immune system are known in eating disorders (EDs), however importance cytokine balance this context has not been clarified. We compared cytokines and growth factors at opposite ends BMI ranges, 90 patients classified relation to BMI, depressive EDs comorbidities. Serum concentrations interleukin (IL)-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), monocyte chemoattractant protein-1 (MCP-1), vascular endothelial...

10.3390/nu11091995 article EN Nutrients 2019-08-23

Lipedema is a pathology of adipose tissue, still unclear etiology and challenging to diagnose. For these reasons, therapeutic approach also complex sometimes controversial. The inflammation state present in lipedema can be limited by controlling the glycemic peaks. Specifically, ketogenic diet (KD) seems have right conditions effective. Herein, we reported subject diagnosed with who, only KD nutritional intervention, achieved significant weight loss (-41 Kg), net decrease body...

10.3390/life11121402 article EN cc-by Life 2021-12-15
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