Shuguang Xu

ORCID: 0000-0003-0861-0754
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About
Contact & Profiles
Research Areas
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Breast Cancer Treatment Studies
  • Medical Research and Treatments
  • Curcumin's Biomedical Applications
  • Dermatological and Skeletal Disorders
  • Ginseng Biological Effects and Applications
  • Medical Imaging Techniques and Applications
  • Neuroendocrine regulation and behavior
  • Angiogenesis and VEGF in Cancer
  • Mesenchymal stem cell research
  • Cancer, Hypoxia, and Metabolism
  • RNA modifications and cancer
  • Cancer, Lipids, and Metabolism
  • Cancer Treatment and Pharmacology
  • Respiratory and Cough-Related Research
  • MRI in cancer diagnosis
  • Cancer-related gene regulation
  • Inflammatory Biomarkers in Disease Prognosis
  • Dermatologic Treatments and Research
  • Plant-based Medicinal Research
  • Lung Cancer Treatments and Mutations
  • Systemic Sclerosis and Related Diseases
  • Traditional Chinese Medicine Analysis
  • Paraquat toxicity studies and treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies

Renji Hospital
2024-2025

Shanghai Jiao Tong University
2024-2025

Ningbo University
2024

Ningbo Medical Center Lihuili Hospital
2024

Nanjing University of Chinese Medicine
2019

Dahua Hospital
2017

Both borneol and gastrodin are bioactive substances derived from traditional Chinese medicine. In this paper, the effect of on distribution to brain in mice via oral administration was investigated. Gastrodin concentrations plasma gastrodigenin (active metabolite gastrodin) were determined by reversed-phase high-performance liquid chromatography, after intragastric (200 mg kg− 1) alone or combined with different doses (200, 400 600 simultaneously same dose (400 given 20 40 min beforehand,...

10.1080/10611860701794395 article EN Journal of drug targeting 2008-01-01

The heterogeneity of breast tumors might reflect biological complexity and provide prediction clues for the sensitivity treatment. This study aimed to construct a model based on tumor in magnetic resonance imaging (MRI) predicting pathological complete response (pCR) neoadjuvant chemotherapy (NAC). retrospective involved 217 patients with biopsy-confirmed invasive cancer who underwent MR before after NAC. Patients were randomly divided into training cohort validation at 1:1 ratio. images...

10.3390/curroncol32020093 article EN cc-by Current Oncology 2025-02-07

Lung cancer is the leading cause of cancer-related mortality globally. N6-methyladenosine (m6A) most abundant modification in mammalian mRNA and involved biological regulation tumors, including lung cancer. However, role m6A-related proteins, such as RNA-binding motif protein 15 (RBM15), progression remains largely unknown. Our study indicated that RBM15 significantly overexpressed adenocarcinoma, serving an independent prognostic factor for poor outcomes facilitating tumor cell...

10.1038/s41388-024-03220-z article EN cc-by-nc-nd Oncogene 2024-11-11

The present study investigated the effects and mechanism by which curcumin suppresses intestinal microvascular endothelial cells (INMECs) invasion angiogenesis induced activated platelets. INMECs were obtained from healthy rats, divided into five groups: Control, platelets, platelets +2.5 µM curcumin, +5.0 +10.0 curcumin. Curcumin toxicity was determined vascular growth factor (VEGF) concentrations of groups measured using ELISA. branch point numbers a capillary tube formation experiment,...

10.3892/etm.2019.7662 article EN Experimental and Therapeutic Medicine 2019-06-11

To investigate the association between lipid ratios and survival outcomes in patients with locally advanced breast cancer (LABC) undergoing neoadjuvant chemotherapy.

10.1080/00325481.2024.2370235 article EN Postgraduate Medicine 2024-06-19

Temporal heterogeneity in human epidermal growth factor receptor 2 (HER2) status may be associated with the prognosis of breast cancer. We aimed to clarify relationship HER2-low transition during neoadjuvant therapy survival outcomes under new classification HER2 status.

10.1080/07853890.2024.2409343 article EN cc-by-nc Annals of Medicine 2024-10-07
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