A5024284257- Prenatal Screening and Diagnostics
- Genomic variations and chromosomal abnormalities
- Ovarian function and disorders
- Carbon and Quantum Dots Applications
- Chromosomal and Genetic Variations
- Reproductive Biology and Fertility
- Electrochemical sensors and biosensors
- Assisted Reproductive Technology and Twin Pregnancy
- Parvovirus B19 Infection Studies
- Reproductive System and Pregnancy
- RNA modifications and cancer
- Advanced Nanomaterials in Catalysis
- Neurogenetic and Muscular Disorders Research
Reproductive & Genetic Hospital CITIC-Xiangya
2013-2023
Central South University
2013-2019
Key Laboratory of Guangdong Province
2016
Guangzhou Medical University
2016
Guangzhou Institute of Dermatology
2016
Guangzhou Women and Children Medical Center
2016
Third Affiliated Hospital of Guangzhou Medical University
2016
National Engineering Research Center of Human Stem Cells
2014
STUDY QUESTIONIs preimplantation genetic diagnosis (PGD) for translocation carriers more effective when done with a single-nucleotide polymorphism (SNP) array using trophectoderm (TE) biopsy and frozen embryo transfer (FET) compared traditional PGD based on fluorescence in situ hybridization (FISH-PGD) blastomere fresh transfer?
Five pregnant women with a child affected by spinal muscular atrophy (SMA) were recruited between November 2014 and March 2015. Deletion of exons 7 and/or 8 in the SMN1 gene identified multiplex ligation-dependent probe amplification (MLPA), current standard diagnostic test for SMA. Parental fetal haplotypes determined each family from haplotype-based non-invasive testing blood samples maternal plasma, respectively. Fetal haplotype was compared results MLPA DNA obtained amniotic fluid or...
Translocation is one of the more common structural rearrangements chromosomes, with a prevalence 0.2%. The two most types chromosomal translocations, Robertsonian and reciprocal, usually result in no obvious phenotypic abnormalities when balanced. However, these are still associated reproductive risks, such as infertility, spontaneous abortion delivery babies mental retardation or developmental delay. In recent years, array-based whole-genome amplification (WGA) technologies, including...
Background: Diabetes Mellitus (DM) is a major public metabolic disease that influences 366 million people in the world 2011, and this number predicted to rise 552 2030. DM clinically diagnosed by fasting blood glucose equal or greater than 7 mM. Therefore, development of effective biosensor has attracted extensive attention worldwide. Fluorescence- based strategies have sparked tremendous interest due their rapid response, facile operation, excellent sensitivity. Many fluorescent compounds...
Abstract Study question Whether letrozole-stimulated protocol has advantages over hormone replacement therapy (HRT) in frozen embryo transfer patients with polycystic ovary syndrome (PCOS)? Summary answer Letrozole-stimulated is more suitable for endometrial preparation than HRT PCOS, which can increase the live birth rate and reduce pregnancy complications. What known already The current routine women PCOS HRT. However, expensive, recent studies have found may risk of adverse maternal...
Abstract Study question Does co-administration of GnRH agonist and Human chorionic gonadotropin(dual trigger) in PGT cycles improve the number usable blastocysts per patient compared to hCG alone? Summary answer Using dual trigger has no effect on undergoing GnRH-ant protocol for triggering with alone. What is known already HCG used at end controlled ovarian hyperstimulation as a surrogate LH surge induce final oocyte maturation. Recently, based retrospective studies, maturation (dual been...