A5004974282- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Hemodynamic Monitoring and Therapy
- Esophageal Cancer Research and Treatment
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Pain Management
- Gastrointestinal Tumor Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Esophageal and GI Pathology
- Intracranial Aneurysms: Treatment and Complications
- Congenital Anomalies and Fetal Surgery
- Cerebrovascular and Carotid Artery Diseases
- Organ Transplantation Techniques and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Venous Thromboembolism Diagnosis and Management
- Hip and Femur Fractures
- Sepsis Diagnosis and Treatment
- Peripheral Artery Disease Management
- Machine Learning in Healthcare
- Metastasis and carcinoma case studies
- Stroke Rehabilitation and Recovery
- Cardiovascular Syncope and Autonomic Disorders
- Cancer, Stress, Anesthesia, and Immune Response
- COVID-19 and healthcare impacts
V.A. Negovsky Scientific Research Institute of General Reanimatology
2024-2025
Moscow City Oncology Hospital №62
2025
P.A. Hertzen Moscow Oncology Research Institute
2014-2023
Ministry of Health of the Russian Federation
2011-2023
Proton pump inhibitors have dose-dependent immunomodulatory effects. We tested the hypothesis that mega-dose esomeprazole therapy would reduce organ dysfunction in patients with sepsis or septic shock. A multinational, randomized, double-blind, placebo-controlled clinical trial. Seventeen ICUs emergency departments three countries. Adult Mega-dose (1024 mg) placebo over a 72-hour period. The primary outcome was mean daily Sequential Organ Failure Assessment (SOFA) score to day 10. Secondary...
Introduction. Despite the advances in modern anesthesiology, it is impossible to guarantee a safe course of anesthesia, and even with planned surgical interventions, there risk death. At present, no unanimity approaches assessing perioperative risk, many systems for determining this have not been validated Russia. The question contribution pre-operative factors likelihood an unfavorable outcome also remains open, which requires large multicenter national studies. Objectives. To assessment...
A significant proportion of patients undergoing non-cardiac surgery receive therapy with angiotensin converting enzyme (ACE) inhibitors/angiotensin II receptor blockers (ARBs), which are usually prescribed for treatment arterial hypertension and CHF. Current guidelines fail to provide clear consensus on whether it is worth discontinuing ACEi/ARBs before surgery. The aim this research was assess the contribution pre-op withdrawal development postoperative complications in after abdominal...
Background. Metabolic changes due to the progression of cancer and its aggressive treatment, lead decreased food intake, related with development anorexia-cachexia syndrome (CACS) because complex interactions between pro-inflammatory cytokines host metabolism. Beyond physical metabolic consequences, patients are often suffering from psychological distress, including depression. Material Methods . A literature search analysis data was conducted in PubMed Medline databases since 2000 purpose...
manipulations and without pericardial opening or resection, the rate of PAF was 25.5% (12/47) 7.3 (25/343), respectively (p=0.001). Perioperative transfusion therapy performed in 15.9% (85/532). In this group, frequency episodes higher accounted for 20% (23/85%) versus 8.7% (39/447) patients who did not need any blood (p=0.01). continuous thoracic epidural analgesia significantly lower than that general anesthesia group [7.9% (15/190) 13.7% (47/342), (p=0.04)]. The intensive care unit (ICU)...
INTRODUCTION. The need for accurate risk stratification is obvious. Modern methods are quite cumbersome, which can cause difficulties when applied in routine practice, and therefore relatively simple but forecasting have become very popular, which, however, not been validated Russia: SORT (Surgical Outcome Risk Tool), SRS Scale), POSPOM (Preoperative Score to Predict Postoperative Mortality), NZRISK (New Zealand RISK), SMPM Mortality Probability Model). OBJECTIVES. aim of this work determine...
Postoperative agitation is common after non-cardiac surgery. It associated with postoperative delirium and cognitive dysfunction, leading to prolonged hospital stay delayed social readjustment. Prevention treatment strategies are lacking. We assessed the efficacy of a novel approach, Wash In/Wash Out procedure, in reducing post-anesthetic agitation. This multicenter, parallel-group, double-blind randomized controlled trial enrolling 200 patients undergoing open abdominal Participants...
The paper describes a rare clinical case of successful simultaneous surgery — esophagectomy and upper lobectomy with resection the primary intermediate bronchi for synchronous cancer thoracic esophagus central right lung. It details diagnostic complex specific morphological features in context differential diagnosis between neoplasia metastatic process. This demonstrates possibility one-stage surgical treatment severe terms its prognosis provided that extent disease patient’s functional...
Objective: to develop an algorithm in order choose a method for anesthesia and its components that minimally affect heart rhythm the cardiac conduction system (CCS) patients at high risk perioperative arrhythmias. Subjects methods. Seventy-five aged 62.2±9.63 years, who received cardiotropic therapy compensation of cardiovascular diseases had undergone surgery abdominal malignancies, were examined. According technique, randomized into 4 groups: 1) (n=16) multimodal intravenous general...
Background. Pain syndrome is the most common complication of thoracotomy. It main reason discomfort in postoperative period and could impair respiratory function. The aim study. our study was to analyze effect PTPS on pulmonary function pneumonia rate patients underwent open surgery lung cancer. Methods. 300 were included operated clinic for cancer via thoracotomy approach. All randomly assigned 3 comparable groups according method anesthesia: thoracic epidural analgesia (HEA), n = 100;...
P. A. Gertsen Scientific Research Oncological Institute, Dept of Anaesthesiology & Intensive Care, Moscow, Russian Federation